Article
Gastroenterology & Hepatology
Qiaoyan Liu, Bo Li, Yikang Li, Yiran Wei, Bingyuan Huang, Jubo Liang, Zhengrui You, You Li, Qiwei Qian, Rui Wang, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, Mingxia Shi, Xiao Xiao, Qixia Wang, Qi Miao, Jing-Yuan Fang, Merrill Eric Gershwin, Min Lian, Xiong Ma, Ruqi Tang
Summary: Comparative analysis of gut microbiome and metabolome in IgG4-SC and PSC patients revealed distinct host-microbe interactions that may contribute to disease pathogenesis, highlighting the uniqueness of IgG4-SC.
Article
Critical Care Medicine
Jean-Remi Lavillegrand, Emmanuelle Mercier-Des-Rochettes, Elodie Baron, Frederic Pene, Damien Contou, Raphael Favory, Sebastien Preau, Arnaud Galbois, Chloe Molliere, Arnaud-Felix Miailhe, Jean Reignier, Mehran Monchi, Claire Pichereau, Sara Thietart, Thibault Vieille, Gael Piton, Gabriel Preda, Idriss Abdallah, Marine Camus, Eric Maury, Bertrand Guidet, Guillaume Dumas, Hafid Ait-Oufella
Summary: In this large retrospective multicenter study, it was found that mortality associated with acute cholangitis decreased significantly over time. Risk factors for in-hospital mortality include severity of organ failure, cause of obstruction, local complications of acute cholangitis, as well as delayed biliary drainage over 48 hours.
Article
Medicine, General & Internal
J. M. Ordonez-Mena, Thomas R. Fanshawe, Dona Foster, Monique Andersson, Sarah Oakley, Nicole Stoesser, A. Sarah Walker, Gail Hayward
Summary: This retrospective cohort study quantified the demand for laboratory microbiology tests in primary care settings, showing that urine culture was the most common test requested and Escherichia coli was the most prevalent organism identified. Antenatal urine cultures and blood tests during pregnancy were also found to be common test combinations. Further research on the feasibility and impact of point-of-care tests for these specimen types is recommended.
Review
Medicine, General & Internal
Stefan Malmberg, Susanna Petren, Ronny Gunnarsson, Katarina Hedin, Paer-Daniel Sundvall
Summary: The findings suggest that FN may be involved in acute sore throat in PHC patients, but the association is much weaker compared to GAS.
Article
Gastroenterology & Hepatology
Menglei Shuai, Yuanqing Fu, Hai-Li Zhong, Wanglong Gou, Zengliang Jiang, Yuhui Liang, Zelei Miao, Jin-Jian Xu, Tien Huynh, Mark L. Wahlqvist, Yu-Ming Chen, Ju-Sheng Zheng
Summary: This study investigated the determinants and long-term stability of the gut mycobiome in middle-aged and elderly individuals. It also explored the ecological links between gut fungi, bacteria, and faecal metabolome, as well as the potential influence of gut fungi on metabolic health through interactions with gut bacterial functions and metabolites. The results showed that the composition of the gut mycobiome was temporally stable and mainly influenced by age, long-term habitual diet, and host physiological states. Dairy consumption was found to be associated with certain gut fungi, while other gut fungi were associated with insulin resistance and blood cholesterol levels through interactions with gut bacterial diversity and faecal histidine.
Article
Pharmacology & Pharmacy
O. Inan, E. S. Sahiner, I. Ates
Summary: The study aimed to determine the risk factors associated with clinical outcomes in geriatric patients with acute cholangitis. It was found that the oldest-old group had higher rates of severe acute cholangitis, ICU hospitalization, and mortality. Factors associated with mortality included the presence of malignancy, ICU hospitalization, decreased platelet levels, decreased hemoglobin levels, and decreased albumin levels.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Mark A. Gromski, Aditya Gutta, Glen A. Lehman, Yan Tong, Evan L. Fogel, James L. Watkins, Jeffrey J. Easler, Benjamin L. Bick, Lee McHenry, Cole Beeler, Ryan F. Relich, Bryan H. Schmitt, Stuart Sherman
Summary: The majority of bile cultures in suspected acute cholangitis patients were positive, with a notable presence of drug-resistant pathogens. Prior biliary endoscopic sphincterotomy was associated with a higher frequency of certain bacterial infections and vancomycin-resistant Enterococcus.
Article
Public, Environmental & Occupational Health
Jane Oliver, Julie Bennett, Sally Thomas, Jane Zhang, Nevil Pierse, Nicole J. Moreland, Deborah A. Williamson, Susan Jack, Michael Baker
Summary: This study found that a GAS-positive throat or skin swab significantly increased the risk of subsequent ARF, especially for Maori and Pacific Peoples. The use of antibiotics did not reduce the risk of ARF following GAS detection.
Review
Medicine, General & Internal
Ayinalem Alemu, Zebenay Workneh Bitew, Getu Diriba, Emebet Gashu, Getachew Seid, Kirubel Eshetu, Abebaw Kebede, Balako Gumi
Summary: This study aims to assess the incidence and predictors of acquired resistance to second-line antituberculosis drugs (SLDs) during multi-drug resistant tuberculosis (MDR-TB) treatment. The study will systematically search and analyze published articles up to March 2023, and will use statistical software to estimate the pooled incidence and effect measures of acquired resistance. The findings will be disseminated through peer-reviewed journals and scientific conferences.
Article
Pediatrics
Rebecca Hilary Proudfoot, Bob Phillips
Summary: This study found a rare incidence of PJP in children treated for malignant disease, with only 32 cases detected in the UK over a 2-year period, and no deaths directly attributed to PJP. Despite prophylaxis with co-trimoxazole, breakthrough infections may occur, which could represent pathogen resistance or non-compliance. Further consideration of PJP prophylaxis during treatment for specific cancers, such as acute myeloid leukaemia and non-Hodgkin's lymphoma, is warranted.
ARCHIVES OF DISEASE IN CHILDHOOD
(2021)
Review
Medicine, General & Internal
Marinjho Emely Jonduo, Lisa Michelle Vallely, Handan Wand, Emma Louise Sweeney, Dianne Egli-Gany, John Kaldor, Andrew John Vallely, Nicola Low
Summary: This systematic review investigates the role of genital mycoplasmas in adverse pregnancy and birth outcomes. The findings suggest that Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum may be associated with preterm birth, low birth weight, premature rupture of membranes, spontaneous abortion, and perinatal or neonatal death.
Review
Medicine, General & Internal
Marinjho Emely Jonduo, Lisa Michelle Vallely, Handan Wand, Emma Louise Sweeney, Dianne Egli-Gany, John Kaldor, Andrew John Vallely, Nicola Low
Summary: This systematic review investigates the role of genital mycoplasmas in adverse pregnancy and birth outcomes, alone or in combination with bacterial vaginosis (BV). The available literature does not provide conclusive evidence, highlighting the need for future studies that consider the interaction between genital mycoplasmas and the vaginal microbiome.
Article
Surgery
Anthony Loria, Alexa D. Melucci, Paul R. Burchard, Aqsa Ghaffar, Elizabeth Levatino, Larissa K. Temple, Fergal J. Fleming
Summary: The impact of a definition change on the rate of acute kidney injuries in the National Surgical Quality Improvement Project was assessed. The study found a 1,700% relative increase in the rate of reported acute kidney injuries after the definition change. Newly identified acute kidney injuries were associated with high complication rates, highlighting the importance of the definition change for patient counseling, research, and quality reporting.
Article
Gastroenterology & Hepatology
Francesca Colapietro, Arianna Bertazzoni, Ana Lleo
Summary: The prevalence and incidence trends of PBC have been influenced by improved diagnostic methods and therapeutic options. However, there is a lack of robust epidemiologic data in African regions, South America, and most of South-East nations. Future research should focus on filling this gap and considering the coexistence of metabolic-associated liver disease.
CLINICS IN LIVER DISEASE
(2022)
Article
Gastroenterology & Hepatology
Szymon Ostrowski, Anthony Croft
Summary: This retrospective study aimed to investigate the impact of viral enteric infection on the severity and outcomes of acute severe ulcerative colitis (ASUC). The results showed that infection with viral enteropathogens did not affect disease severity at presentation, the need for rescue therapy, or the success rate of rescue therapy in ASUC patients.
JOURNAL OF CROHNS & COLITIS
(2022)
Review
Rheumatology
Nobuya Abe, Kenji Oku, Olga Amengual, Yuichiro Fujieda, Masaru Kato, Toshiyuki Bohgaki, Shinsuke Yasuda, Rintaro Mori, Eriko Morishita, Katsue Suzuki-Inoue, Tatsuya Atsumi
MODERN RHEUMATOLOGY
(2020)
Article
Multidisciplinary Sciences
Masahiro Tsuji, Mariko Sawada, Shinichi Watabe, Hiroyuki Sano, Masayo Kanai, Emi Tanaka, Satoshi Ohnishi, Yoshiaki Sato, Hisanori Sobajima, Takashi Hamazaki, Rintaro Mori, Akira Oka, Hiroyuki Ichiba, Masahiro Hayakawa, Satoshi Kusuda, Masanori Tamura, Makoto Nabetani, Haruo Shintaku
SCIENTIFIC REPORTS
(2020)
Article
Pediatrics
Narumi Motegi, Naho Morisaki, Maiko Suto, Hiroshi Tamai, Rintaro Mori, Takeo Nakayama
Summary: Over the past 20 years, the average lifespan of individuals with Down syndrome in Japan has increased, with 1 in 3 now living past the age of 60, indicating the need for more social welfare services in this aging population.
PEDIATRICS INTERNATIONAL
(2021)
Article
Medicine, Research & Experimental
Olukunmi Omobolanle Balogun, Caroline Kaori Tomo, Keiji Mochida, Masashi Mikami, Henda da Rosa Vasconcelos, Isilda Neves, Hisakazu Hiraoka, Hirotsugu Aiga, Rintaro Mori, Kenji Takehara
Review
Public, Environmental & Occupational Health
Xiuting Mo, Ruoyan Gai Tobe, Yoshimitsu Takahashi, Naoko Arata, Tippawan Liabsuetrakul, Takeo Nakayama, Rintaro Mori
Summary: This study aimed to find evidence of the cost-effectiveness of gestational diabetes mellitus (GDM) screening and assessed the quality of current economic evaluations. Most studies found GDM screening to be cost-effective, though uncertainties remain due to many factors. The quality assessment identified weaknesses in the economic evaluations in terms of integrating existing data, measuring costs and consequences, analyzing perspectives, and adjusting for uncertainties.
JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Psychiatry
Ai Aoki, Togoobaatar Ganchimeg, Nyam Naranbaatar, Zuunnast Khishigsuren, Lkagvasuren Gundegmaa, Shagdar Bat-Erdene, Bolorchimeg Munkhbaatar, Rintaro Mori, Akihito Kikuchi, Hideaki Soya, Kiyoto Kasai, Kenji Takehara
Summary: This study validated the effectiveness of SDQ in Mongolian school-age children, with a recommended cut-off score of 16/17 for screening mental health problems among community children.
Article
Education & Educational Research
Maiko Suto, Celine Miyazaki, Yuko Yanagawa, Kenji Takehara, Tsuguhiko Kato, Ruoyan Gai, Erika Ota, Rintaro Mori
Summary: Universal prevention approaches targeting general population can effectively promote children's health. Evidence from reviews of school-based interventions suggests positive effects such as vision screening and provision of free spectacles, and a combination of social competence and social influence methods to prevent illicit drug use.
JOURNAL OF SCHOOL HEALTH
(2021)
Article
Psychiatry
Ai Aoki, Ganchimeg Togoobaatar, Anudari Tseveenjav, Naranbaatar Nyam, Khishigsuren Zuunnast, Gundegmaa Lkhagvasuren, Bat-Erdene Shagdar, Rintaro Mori, Akihito Kikuchi, Hideaki Soya, Kiyoto Kasai, Kenji Takehara
Summary: This study examined the association between socioeconomic and lifestyle factors with mental health problems among school-age children in Mongolia. The results showed that male gender, low maternal education, short sleep, lack of physical activity, and long screen time were associated with a higher risk of mental health problems. The findings suggest the presence of globally common socioeconomic and lifestyle risk factors, and may help in developing targeted preventive interventions for high-risk groups and promoting a healthy lifestyle in Mongolia.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Correction
Pediatrics
Tomohisa Ando, Rintaro Mori, Kenji Takehara, Mari Asukata, Shuichi Ito, Akira Oka
JMIR PEDIATRICS AND PARENTING
(2022)
Article
Pediatrics
Tomohisa Ando, Rintaro Mori, Kenji Takehara, Mari Asukata, Shuichi Ito, Akira Oka
Summary: This study evaluated the effectiveness of pediatric teleconsultation for preventing atopic dermatitis (AD) in infants and reducing parenting stress in mothers in Japan. The findings highlight the potential of combining routine pediatric care with teleconsultation and email newsletters as a new strategy for preventing AD.
JMIR PEDIATRICS AND PARENTING
(2022)
Review
Medicine, General & Internal
Naohiro Yonemoto, Shuko Nagai, Rintaro Mori
Summary: The effects of home visits on maternal and neonatal mortality during the early postpartum period are uncertain, with low certainty of evidence. Individualised care as part of home visits may improve postnatal depression scores and breastfeeding rates, but further well-designed trials are needed.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Medicine, Research & Experimental
Ryusei Matsuyama, Kenichi Matsuo, Ryutaro Mori, Mitsutaka Sugita, Naotaka Yamaguchi, Toru Kubota, Kunio Kameda, Yasuhisa Mochizuki, Ryo Takagawa, Toshiaki Kadokura, Goro Matsuda, Noriyuki Kamiya, Itaru Endo
Summary: This study conducted in a Japanese region suggests that the indication for re-resection for IGBC should not solely rely on the pT-factor, but should also consider pathological and intraoperative findings at prior cholecystectomy.
Article
Public, Environmental & Occupational Health
Shuhei Nomura, Yoshiko Yamamoto, Daisuke Yoneoka, Juanita A. Haagsma, Joshua A. Salomon, Peter Ueda, Rintaro Mori, Damian Santomauro, Theo Vos, Kenji Shibuya
Summary: This study conducted a survey in Japan to estimate Disability Weights (DWs) for various health states and found a high correlation between Japanese DWs and GBD 2013 DWs, with considerable disagreements. Compared to the GBD study, Japanese DWs were higher for injury-related health states and lower for mental, behavioral, and substance use disorders.
POPULATION HEALTH METRICS
(2021)
Review
Medicine, General & Internal
Shoichiro Amari, Sadequa Shahrook, Fumihiko Namba, Erika Ota, Rintaro Mori
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2020)
Review
Medicine, General & Internal
Erika Ota, Katharina da Silva Lopes, Philippa Middleton, Vicki Flenady, Windy M. Wariki, Md Obaidur Rahman, Ruoyan Tobe-Gai, Rintaro Mori
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2020)
