Prophylactic tributyrin treatment mitigates chronic-binge ethanol-induced intestinal barrier and liver injury

Rapid disruption of intestinal epithelial tight junction and barrier dysfunction by ionizing radiation in mouse colon in vivo: protection by N-acetyl-l-cysteine

(2016) Pradeep K. Shukla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cellular zinc is required for intestinal epithelial barrier maintenance via the regulation of claudin-3 and occludin expression

(2016) Yuka Miyoshi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

GPR41 and GPR43 in Obesity and Inflammation – Protective or Causative?

(2016) Zhiwei Ang et al.   Frontiers in Immunology

Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans

(2015) Jose Antonio López-Moreno et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration

(2015) Yoon Seok Roh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

(2015) Peng Chen et al.   GASTROENTEROLOGY

Tributyrin Supplementation Protects Mice from Acute Ethanol-Induced Gut Injury

(2014) Gail A. Cresci et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway

(2013) A. de Conti et al.   CARCINOGENESIS

Alcoholic liver disease: Pathogenesis, management, and novel targets for therapy

(2013) Eric S Orman et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Lactobacillus GG and Tributyrin Supplementation Reduce Antibiotic-Induced Intestinal Injury

(2013) Gail Cresci et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Chronic Ethanol Consumption Alters Mammalian Gastrointestinal Content Metabolites

(2013) Guoxiang Xie et al.   JOURNAL OF PROTEOME RESEARCH

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment

(2013) Lara Bull-Otterson et al.   PLoS One

Binge Alcohol-Induced Microvesicular Liver Steatosis and Injury are Associated with Down-Regulation of Hepatic Hdac1, 7, 9, 10, 11 and Up-Regulation of Hdac3

(2012) Irina Kirpich et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Fast Renewal of the Distal Colonic Mucus Layers by the Surface Goblet Cells as Measured by In Vivo Labeling of Mucin Glycoproteins

(2012) Malin E. V. Johansson   PLoS One

Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis

(2012) Rodrigo Goulart Pacheco   WORLD JOURNAL OF GASTROENTEROLOGY

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

(2011) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

(2011) Roberto Berni Canani   WORLD JOURNAL OF GASTROENTEROLOGY

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

(2010) Arthur W. Yan et al.   HEPATOLOGY

Intestinal Dysbiosis: A Possible Mechanism of Alcohol-Induced Endotoxemia and Alcoholic Steatohepatitis in Rats

(2009) Ece Mutlu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

Physiological concentrations of short-chain fatty acids immediately suppress colonic epithelial permeability

(2008) Takuya Suzuki et al.   BRITISH JOURNAL OF NUTRITION

Sodium-Coupled Transport of the Short Chain Fatty Acid Butyrate by SLC5A8 and Its Relevance to Colon Cancer

(2008) Muthusamy Thangaraju et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats

(2008) Ali Keshavarzian et al.   JOURNAL OF HEPATOLOGY