Determining an optimal clinical dose of elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled randomized clinical trial

Bowel Disorders

(2016) Brian E. Lacy et al.   GASTROENTEROLOGY

Constipation

(2016) Arnold Wald   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence and Self-recognition of Chronic Constipation: Results of an Internet Survey

(2016) Akio Tamura et al.   Journal of Neurogastroenterology and Motility

Specific inhibition of bile acid transport alters plasma lipids and GLP-1

(2015) Mats Rudling et al.   BMC Cardiovascular Disorders

Elobixibat and its potential role in chronic idiopathic constipation

(2014) Andres Acosta et al.   Therapeutic Advances in Gastroenterology

Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation - a double-blind study

(2011) M. Simrén et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prevalence of and Risk Factors for, Chronic Idiopathic Constipation in the Community: Systematic Review and Meta-analysis

(2011) Nicole C Suares et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Females With Functional Constipation

(2011) Banny S Wong et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation

(2011) William D Chey et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Constipation and Risk of Cardiovascular Disease among Postmenopausal Women

(2011) Elena Salmoirago-Blotcher et al.   AMERICAN JOURNAL OF MEDICINE

Impact of Chronic Constipation on Health-Related Quality of Life, Work Productivity, and Healthcare Resource Use: An Analysis of the National Health and Wellness Survey

(2011) Shawn X. Sun et al.   DIGESTIVE DISEASES AND SCIENCES

Epidemiology of constipation in Europe and Oceania: a systematic review

(2009) George Peppas et al.   BMC GASTROENTEROLOGY

Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation

(2008) Francesco Raimondi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY