Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

K27M-mutant histone-3 as a novel target for glioma immunotherapy

(2017) Katharina Ochs et al.   OncoImmunology

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Targeting the tumour profile using broad spectrum chimaeric antigen receptor T-cells

(2016) Shoba A. Navai et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular pathology of paediatric central nervous system tumours

(2016) Jason CH Chiang et al.   JOURNAL OF PATHOLOGY

Epidermal growth factor receptor targeting and challenges in glioblastoma

(2016) Amy Haseley Thorne et al.   NEURO-ONCOLOGY

Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010

(2016) Adah S. Zhang et al.   NEURO-ONCOLOGY

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

(2016) Eric Tran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations

(2015) David A. Solomon et al.   BRAIN PATHOLOGY

Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

(2015) Michal Bassani-Sternberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

(2015) Jarrett J Adams et al.   NATURE IMMUNOLOGY

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Immunogenicity of somatic mutations in human gastrointestinal cancers

(2015) E. Tran et al.   SCIENCE

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

(2015) Laura A. Johnson et al.   Science Translational Medicine

Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival

(2015) Sabrina Genßler et al.   OncoImmunology

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

(2014) Michael E. Birnbaum et al.   CELL

A vaccine targeting mutant IDH1 induces antitumour immunity

(2014) Theresa Schumacher et al.   NATURE

STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment

(2014) T. Ohkuri et al.   Cancer Immunology Research

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma

(2013) David A Reardon et al.   Expert Review of Vaccines

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology

(2013) Kristin M. Schroeder et al.   PEDIATRIC RESEARCH

Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells

(2013) B. J. Cameron et al.   Science Translational Medicine

Management of Diffuse Pontine Gliomas in Children: Recent Developments

(2013) Rejin Kebudi et al.   PEDIATRIC DRUGS

Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts

(2013) Masasuke Ohno et al.   Journal for ImmunoTherapy of Cancer

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

(2012) Dong-Anh Khuong-Quang et al.   ACTA NEUROPATHOLOGICA

Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies

(2012) Milos Aleksic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression

(2012) Sachiko Okamoto et al.   Molecular Therapy-Nucleic Acids

Genetic engineering with T cell receptors

(2011) Ling Zhang et al.   ADVANCED DRUG DELIVERY REVIEWS

Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners

(2010) Xinmei Zhu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis

(2010) Maria R Parkhurst et al.   MOLECULAR THERAPY

T cell receptor gene therapy: strategies for optimizing transgenic TCR pairing

(2010) Coen Govers et al.   TRENDS IN MOLECULAR MEDICINE

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

(2009) L. A. Johnson et al.   BLOOD

Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR

(2009) S. Okamoto et al.   CANCER RESEARCH