The biochemistry and molecular biology of chlorophyll breakdown

Pathogen-Induced Leaf Chlorosis: Products of Chlorophyll Breakdown Found in Degreened Leaves of Phytoplasma-Infected Apple (Malus × domestica Borkh.) and Apricot (Prunus armeniaca L.) Trees Relate to the Pheophorbide a Oxygenase/Phyllobilin Pathway

(2017) Cecilia Mittelberger et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Suppressor of Overexpression of CO 1 Negatively Regulates Dark-Induced Leaf Degreening and Senescence by Directly Repressing Pheophytinase and Other Senescence-Associated Genes in Arabidopsis

(2017) Junyi Chen et al.   PLANT PHYSIOLOGY

A Novel Chemical Inhibitor of ABA Signaling Targets All ABA Receptors

(2017) Yajin Ye et al.   PLANT PHYSIOLOGY

Breakdown of Chlorophyll in Higher Plants-Phyllobilins as Abundant, Yet Hardly Visible Signs of Ripening, Senescence, and Cell Death

(2016) Bernhard Kräutler   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Crystal structure of methylesterase family member 16 (MES16) from Arabidopsis thaliana

(2016) Hongmei Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chlorophyll Catabolites in Senescent Leaves of the Plum Tree (Prunus domestica)

(2016) Theresia Erhart et al.   CHEMISTRY & BIODIVERSITY

Chlorophyll Catabolites in Fall Leaves of the Wych Elm Tree Present a Novel Glycosylation Motif

(2016) Mathias Scherl et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chlorophyll catabolism in olive fruits (var. Arbequina and Hojiblanca) during maturation

(2016) Honorio Vergara-Domínguez et al.   FOOD CHEMISTRY

NON-YELLOWING2 (NYE2), a Close Paralog of NYE1, Plays a Positive Role in Chlorophyll Degradation in Arabidopsis

(2016) Shouxin Wu et al.   Molecular Plant

ABF2, ABF3, and ABF4 Promote ABA-Mediated Chlorophyll Degradation and Leaf Senescence by Transcriptional Activation of Chlorophyll Catabolic Genes and Senescence-Associated Genes in Arabidopsis

(2016) Shan Gao et al.   Molecular Plant

Dark-induced leaf senescence: new insights into a complex light-dependent regulatory pathway

(2016) Daniela Liebsch et al.   NEW PHYTOLOGIST

Identification of a Chlorophyll Dephytylase Involved in Chlorophyll Turnover in Arabidopsis

(2016) Yao-Pin Lin et al.   PLANT CELL

Arabidopsis STAY-GREEN , Mendel’s Green Cotyledon Gene, Encodes Magnesium-Dechelatase

(2016) Yousuke Shimoda et al.   PLANT CELL

A Role for TIC55 as a Hydroxylase of Phyllobilins, the Products of Chlorophyll Breakdown during Plant Senescence

(2016) Mareike Hauenstein et al.   PLANT CELL

The role of ANAC072 in the regulation of chlorophyll degradation during age- and dark-induced leaf senescence

(2016) Shou Li et al.   PLANT CELL REPORTS

Involvement of an ethylene response factor in chlorophyll degradation during citrus fruit degreening

(2016) Xue-ren Yin et al.   PLANT JOURNAL

A liquid chromatography-mass spectrometry platform for the analysis of phyllobilins, the major degradation products of chlorophyll inArabidopsis thaliana

(2016) Bastien Christ et al.   PLANT JOURNAL

Chlorophyll a is a favorable substrate for Chlamydomonas Mg-dechelatase encoded by STAY-GREEN

(2016) Kaori Matsuda et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

ABA receptor PYL9 promotes drought resistance and leaf senescence

(2016) Yang Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NAC transcription factor ANAC046 is a positive regulator of chlorophyll degradation and senescence in Arabidopsis leaves

(2016) Chihiro Oda-Yamamizo et al.   Scientific Reports

The Arabidopsis transcription factor ABIG1 relays ABA signaled growth inhibition and drought induced senescence

(2016) Tie Liu et al.   eLife

Hydroxymethylated Dioxobilins in SenescentArabidopsis thalianaLeaves: Sign of a Puzzling Biosynthetic Intermezzo of Chlorophyll Breakdown

(2015) Iris Süssenbacher et al.   CHEMISTRY-A EUROPEAN JOURNAL

Colorless Chlorophyll Catabolites in Senescent Florets of Broccoli (Brassica oleracea var. italica)

(2015) Matthias H. Roiser et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chlorophyll catabolites in conditioned media of green microalga Desmodesmus subspicatus

(2015) Krzysztof Grabski et al.   JOURNAL OF APPLIED PHYCOLOGY

Functional characterization and hormonal regulation of thePHEOPHYTINASEgeneLpPPHcontrolling leaf senescence in perennial ryegrass

(2015) Jing Zhang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis

(2015) Tiancong Qi et al.   PLANT CELL

Arabidopsis NAC016 promotes chlorophyll breakdown by directly upregulating STAYGREEN1 transcription

(2015) Yasuhito Sakuraba et al.   PLANT CELL REPORTS

Jasmonic acid promotes degreening via MYC2/3/4- and ANAC019/055/072-mediated regulation of major chlorophyll catabolic genes

(2015) Xiaoyu Zhu et al.   PLANT JOURNAL

SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence

(2015) Hironori Takasaki et al.   PLANT JOURNAL

An abscisic acid inducible Arabidopsis MAPKKK, MAPKKK18 regulates leaf senescence via its kinase activity

(2015) Daisuke Matsuoka et al.   PLANT MOLECULAR BIOLOGY

Reexamination of Chlorophyllase Function Implies Its Involvement in Defense against Chewing Herbivores

(2015) Xueyun Hu et al.   PLANT PHYSIOLOGY

PHYTOCHROME-INTERACTING FACTOR 5 (PIF5) positively regulates dark-induced senescence and chlorophyll degradation in Arabidopsis

(2015) Yongqiang Zhang et al.   PLANT SCIENCE

Systematic HPLC/ESI-High Resolution-qTOF-MS Methodology for Metabolomic Studies in Nonfluorescent Chlorophyll Catabolites Pathway

(2015) José Julián Ríos et al.   Journal of Analytical Methods in Chemistry

EIN3 and ORE1 Accelerate Degreening during Ethylene-Mediated Leaf Senescence by Directly Activating Chlorophyll Catabolic Genes in Arabidopsis

(2015) Kai Qiu et al.   PLoS Genetics

Oil accumulation mechanisms of the oleaginous microalga Chlorella protothecoides revealed through its genome, transcriptomes, and proteomes

(2014) Chunfang Gao et al.   BMC GENOMICS

Phyllobilins – the abundant bilin-type tetrapyrrolic catabolites of the green plant pigment chlorophyll

(2014) Bernhard Kräutler   CHEMICAL SOCIETY REVIEWS

Stereo- and Regioselective Phyllobilane Oxidation in Leaf Homogenates of the Peace Lily (Spathiphyllum wallisii): Hypothetical Endogenous Path to Yellow Chlorophyll Catabolites

(2014) Clemens Vergeiner et al.   CHEMISTRY-A EUROPEAN JOURNAL

ArabidopsisSTAYGREEN-LIKE (SGRL) promotes abiotic stress-induced leaf yellowing during vegetative growth

(2014) Yasuhito Sakuraba et al.   FEBS LETTERS

Non-fluorescent chlorophyll catabolites in quince fruits

(2014) José Julián Ríos et al.   FOOD RESEARCH INTERNATIONAL

Structure elucidation of chlorophyll catabolites (phyllobilins) by ESI-mass spectrometry—Pseudo-molecular ions and fragmentation analysis of a nonfluorescent chlorophyll catabolite (NCC)

(2014) Thomas Müller et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Nonfluorescent Chlorophyll Catabolites in Loquat Fruits (Eriobotrya japonica Lindl.)

(2014) José Julián Ríos et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Gene regulatory cascade of senescence-associated NAC transcription factors activated by ETHYLENE-INSENSITIVE2-mediated leaf senescence signalling in Arabidopsis

(2014) Hyo Jung Kim et al.   JOURNAL OF EXPERIMENTAL BOTANY

Mutation ofOryza sativa CORONATINE INSENSITIVE 1b(OsCOI1b) delays leaf senescence

(2014) Sang-Hwa Lee et al.   Journal of Integrative Plant Biology

Age-Triggered and Dark-Induced Leaf Senescence Require the bHLH Transcription Factors PIF3, 4, and 5

(2014) Yi Song et al.   Molecular Plant

Arabidopsis STAY-GREEN2 Is a Negative Regulator of Chlorophyll Degradation during Leaf Senescence

(2014) Yasuhito Sakuraba et al.   Molecular Plant

Photochemical studies of a fluorescent chlorophyll catabolite – source of bright blue fluorescence in plant tissue and efficient sensitizer of singlet oxygen

(2014) Steffen Jockusch et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Arabidopsis WRKY57 Functions as a Node of Convergence for Jasmonic Acid- and Auxin-Mediated Signaling in Jasmonic Acid-Induced Leaf Senescence

(2014) Y. Jiang et al.   PLANT CELL

A NAP-AAO3 Regulatory Module Promotes Chlorophyll Degradation via ABA Biosynthesis inArabidopsisLeaves

(2014) Jiading Yang et al.   PLANT CELL

Water deficit induces chlorophyll degradation via the ‘PAO/phyllobilin’ pathway in leaves of homoio- (Craterostigma pumilum) and poikilochlorophyllous (Xerophyta viscosa) resurrection plants

(2014) BASTIEN CHRIST et al.   PLANT CELL AND ENVIRONMENT

Different Mechanisms Are Responsible for Chlorophyll Dephytylation during Fruit Ripening and Leaf Senescence in Tomato

(2014) Luzia Guyer et al.   PLANT PHYSIOLOGY

Chlorophyll Degradation: The Tocopherol Biosynthesis-Related Phytol Hydrolase in Arabidopsis Seeds Is Still Missing

(2014) Wei Zhang et al.   PLANT PHYSIOLOGY

OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice

(2014) Chengzhen Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phytochrome-interacting transcription factors PIF4 and PIF5 induce leaf senescence in Arabidopsis

(2014) Yasuhito Sakuraba et al.   Nature Communications

Risk Management by Organisms of the Phototoxicity of Chlorophylls

(2013) Yuichiro Kashiyama et al.   CHEMISTRY LETTERS

Hydroxymethylated Phyllobilins: A Puzzling New Feature of the Dioxobilin Branch of Chlorophyll Breakdown

(2013) Iris Süssenbacher et al.   CHEMISTRY-A EUROPEAN JOURNAL

132,173-Cyclopheophorbidebenol as a catabolite of chlorophyllbin phycophagy by protists

(2013) Yuichiro Kashiyama et al.   FEBS LETTERS

Proteomic analysis of chromoplasts from six crop species reveals insights into chromoplast function and development

(2013) Yong-Qiang Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Involvement of Pheophytinase in Ethylene-Mediated Chlorophyll Degradation in the Peel of Harvested ‘Yali’ Pear

(2013) Yudou Cheng et al.   JOURNAL OF PLANT GROWTH REGULATION

Mechanism and Significance of Chlorophyll Breakdown

(2013) Bastien Christ et al.   JOURNAL OF PLANT GROWTH REGULATION

Stay-green plants: what do they tell us about the molecular mechanism of leaf senescence

(2013) Makoto Kusaba et al.   PHOTOSYNTHESIS RESEARCH

Cytochrome P450 CYP89A9 Is Involved in the Formation of Major Chlorophyll Catabolites during Leaf Senescence inArabidopsis

(2013) Bastien Christ et al.   PLANT CELL

ETHYLENE-INSENSITIVE3 Is a Senescence-Associated Gene That Accelerates Age-Dependent Leaf Senescence by Directly Repressing miR164 Transcription in Arabidopsis

(2013) Z. Li et al.   PLANT CELL

Concerted evolution ofD1andD2to regulate chlorophyll degradation in soybean

(2013) Chao Fang et al.   PLANT JOURNAL

ABI3 controls embryo degreening through Mendel's I locus

(2013) F. Delmas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlorophyll Catabolites in Senescent Leaves of the Lime Tree (Tilia cordata)

(2012) Mathias Scherl et al.   CHEMISTRY & BIODIVERSITY

Demetalation of Chlorophyll Pigments

(2012) Yoshitaka Saga et al.   CHEMISTRY & BIODIVERSITY

Structures of Chlorophyll Catabolites in Bananas (Musa acuminata)Reveal a Split Path of Chlorophyll Breakdown in a Ripening Fruit

(2012) Simone Moser et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy

(2012) L. E. Xodo et al.   CURRENT MEDICINAL CHEMISTRY

Interaction between BZR1 and PIF4 integrates brassinosteroid and environmental responses

(2012) Eunkyoo Oh et al.   NATURE CELL BIOLOGY

Disruption ofOPR7andOPR8Reveals the Versatile Functions of Jasmonic Acid in Maize Development and Defense

(2012) Yuanxin Yan et al.   PLANT CELL

STAY-GREEN and Chlorophyll Catabolic Enzymes Interact at Light-Harvesting Complex II for Chlorophyll Detoxification during Leaf Senescence in Arabidopsis

(2012) Y. Sakuraba et al.   PLANT CELL

Conversion of chlorophyllbto chlorophyllaprecedes magnesium dechelation for protection against necrosis in Arabidopsis

(2012) Yousuke Shimoda et al.   PLANT JOURNAL

Chlorophyll b Reductase Plays an Essential Role in Maturation and Storability of Arabidopsis Seeds

(2012) S. Nakajima et al.   PLANT PHYSIOLOGY

Ubiquity and quantitative significance of detoxification catabolism of chlorophyll associated with protistan herbivory

(2012) Y. Kashiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Dioxobilane as Product of a Divergent Path of Chlorophyll Breakdown in Norway Maple

(2011) Thomas Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chlorophyll cycle regulates the construction and destruction of the light-harvesting complexes

(2011) Ryouichi Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

How the Colourless ‘Nonfluorescent’ Chlorophyll Catabolites Rust

(2011) Markus Ulrich et al.   CHEMISTRY-A EUROPEAN JOURNAL

The ELF4–ELF3–LUX complex links the circadian clock to diurnal control of hypocotyl growth

(2011) Dmitri A. Nusinow et al.   NATURE

Dual N- and C-Terminal Processing of Citrus Chlorophyllase Precursor Within the Plastid Membranes leads to the Mature Enzyme

(2011) T. Azoulay-Shemer et al.   PLANT AND CELL PHYSIOLOGY

Age-Dependent Action of an ABA-Inducible Receptor Kinase, RPK1, as a Positive Regulator of Senescence in Arabidopsis Leaves

(2011) In Chul Lee et al.   PLANT AND CELL PHYSIOLOGY

Identification of the 7-Hydroxymethyl ChlorophyllaReductase of the Chlorophyll Cycle inArabidopsis

(2011) Miki Meguro et al.   PLANT CELL

High-Resolution Temporal Profiling of Transcripts during Arabidopsis Leaf Senescence Reveals a Distinct Chronology of Processes and Regulation

(2011) E. Breeze et al.   PLANT CELL

MES16, a Member of the Methylesterase Protein Family, Specifically Demethylates Fluorescent Chlorophyll Catabolites during Chlorophyll Breakdown in Arabidopsis

(2011) B. Christ et al.   PLANT PHYSIOLOGY

An Abscisic Acid-AtNAP Transcription Factor-SAG113 Protein Phosphatase 2C Regulatory Chain for Controlling Dehydration in Senescing Arabidopsis Leaves

(2011) K. Zhang et al.   PLANT PHYSIOLOGY

Horseradish peroxidase-catalyzed oxidation of chlorophyll a with hydrogen peroxide

(2010) Paavo H. Hynninen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Characteristics of the tomato chromoplast revealed by proteomic analysis

(2010) Cristina Barsan et al.   JOURNAL OF EXPERIMENTAL BOTANY

Crystal Structures of the Substrate-Bound Forms of Red Chlorophyll Catabolite Reductase: Implications for Site-Specific and Stereospecific Reaction

(2010) Masakazu Sugishima et al.   JOURNAL OF MOLECULAR BIOLOGY

Chlorophyllase versus pheophytinase as candidates for chlorophyll dephytilation during senescence of broccoli

(2010) Agustin M. Büchert et al.   JOURNAL OF PLANT PHYSIOLOGY

Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in Arabidopsis

(2010) Luis A. J. Mur et al.   NEW PHYTOLOGIST

Cytosolic pyruvate,orthophosphate dikinase functions in nitrogen remobilization during leaf senescence and limits individual seed growth and nitrogen content

(2010) Lucy Taylor et al.   PLANT JOURNAL

The Role of Arabidopsis Rubisco Activase in Jasmonate-Induced Leaf Senescence

(2010) X. Shan et al.   PLANT PHYSIOLOGY

Redox extends its regulatory reach to chloroplast protein import

(2010) Mónica Balsera et al.   TRENDS IN PLANT SCIENCE

Evolution of plant senescence

(2009) Howard Thomas et al.   BMC EVOLUTIONARY BIOLOGY

A Combinatorial Interplay Among the 1-Aminocyclopropane-1-Carboxylate Isoforms Regulates Ethylene Biosynthesis in Arabidopsis thaliana

(2009) A. Tsuchisaka et al.   GENETICS

Participation of ChlorophyllbReductase in the Initial Step of the Degradation of Light-harvesting Chlorophylla/b-Protein Complexes inArabidopsis

(2009) Yukiko Horie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Red Chlorophyll Catabolite Reductase: Enlargement of the Ferredoxin-Dependent Bilin Reductase Family

(2009) Masakazu Sugishima et al.   JOURNAL OF MOLECULAR BIOLOGY

A survey of cultivated heirloom tomato varieties identifies four new mutant alleles at the green-flesh locus

(2009) Cornelius S. Barry et al.   MOLECULAR BREEDING

In vivo Studies on the Roles of Tic55-Related Proteins in Chloroplast Protein Import in Arabidopsis thaliana

(2009) Patrik Boij et al.   Molecular Plant

Light-Independent Cell Death Induced by Accumulation of Pheophorbide a in Arabidopsis thaliana

(2009) M. Hirashima et al.   PLANT AND CELL PHYSIOLOGY

Pheophytin Pheophorbide Hydrolase (Pheophytinase) Is Involved in Chlorophyll Breakdown during Leaf Senescence in Arabidopsis

(2009) S. Schelbert et al.   PLANT CELL

Identification of a novel E3 ubiquitin ligase that is required for suppression of premature senescence in Arabidopsis

(2009) Sabine Raab et al.   PLANT JOURNAL

Defect in non-yellow coloring 3, an α/β hydrolase-fold family protein, causes a stay-green phenotype during leaf senescence in rice

(2009) Ryouhei Morita et al.   PLANT JOURNAL

The stay-green revolution: Recent progress in deciphering the mechanisms of chlorophyll degradation in higher plants

(2009) Cornelius S. Barry   PLANT SCIENCE

Fluorescent chlorophyll catabolites in bananas light up blue halos of cell death

(2009) S. Moser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phytochromes promote seedling light responses by inhibiting four negatively-acting phytochrome-interacting factors

(2009) J. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trifurcate Feed-Forward Regulation of Age-Dependent Cell Death Involving miR164 in Arabidopsis

(2009) J. H. Kim et al.   SCIENCE

Stay-green regulates chlorophyll and chlorophyll-binding protein degradation during senescence

(2009) Stefan Hörtensteiner   TRENDS IN PLANT SCIENCE

Chlorophyll Breakdown by a Biomimetic Route

(2008) Michael Oberhuber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Blue Luminescence of Ripening Bananas

(2008) Simone Moser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple Phytochrome-Interacting bHLH Transcription Factors Repress Premature Seedling Photomorphogenesis in Darkness

(2008) Pablo Leivar et al.   CURRENT BIOLOGY

Chlorophyll Catabolites - Chemical and Structural Footprints of a Fascinating Biological Phenomenon

(2008) Simone Moser et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Expression of the β-oxidation gene 3-ketoacyl-CoA thiolase 2 (KAT2) is required for the timely onset of natural and dark-induced leaf senescence in Arabidopsis

(2008) Mari Cruz Castillo et al.   JOURNAL OF EXPERIMENTAL BOTANY

A yellow chlorophyll catabolite is a pigment of the fall colours

(2008) Simone Moser et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Two short-chain dehydrogenase/reductases, NON-YELLOW COLORING 1 and NYC1-LIKE, are required for chlorophyll band light-harvesting complex II degradation during senescence in rice

(2008) Yutaka Sato et al.   PLANT JOURNAL

Stay-green protein, defective in Mendel’s green cotyledon mutant, acts independent and upstream of pheophorbide a oxygenase in the chlorophyll catabolic pathway

(2008) Sylvain Aubry et al.   PLANT MOLECULAR BIOLOGY

Citrus Chlorophyllase Dynamics at Ethylene-Induced Fruit Color-Break: A Study of Chlorophyllase Expression, Posttranslational Processing Kinetics, and in Situ Intracellular Localization

(2008) T. Azoulay Shemer et al.   PLANT PHYSIOLOGY

Inactive Methyl Indole-3-Acetic Acid Ester Can Be Hydrolyzed and Activated by Several Esterases Belonging to the AtMES Esterase Family of Arabidopsis

(2008) Y. Yang et al.   PLANT PHYSIOLOGY

Control of Jasmonate Biosynthesis and Senescence by miR319 Targets

(2008) Carla Schommer et al.   PLOS BIOLOGY