AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/ -Catenin/Axin2 Pathway

(2016) Y. Li et al.   CANCER RESEARCH

Antiangiogenic 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas Inhibit MCF-7 and MDA-MB-231 Human Breast Cancer Cell Lines Through PI3K/Akt and MAPK/Erk Pathways

(2016) Vera A. Machado et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intratumor partitioning and texture analysis of dynamic contrast-enhanced (DCE)-MRI identifies relevant tumor subregions to predict pathological response of breast cancer to neoadjuvant chemotherapy

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Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells

(2016) Zhongyuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

(2016) Bernard Pereira et al.   Nature Communications

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies

(2016) Xun Chen et al.   Journal of Cancer

miR-26a suppresses tumour proliferation and metastasis by targeting metadherin in triple negative breast cancer

(2015) Peng Liu et al.   CANCER LETTERS

Regulation of c-Myc Expression by Ahnak Promotes Induced Pluripotent Stem Cell Generation

(2015) Hee Jung Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Breast Tumor Heterogeneity: Source of Fitness, Hurdle for Therapy

(2015) Shany Koren et al.   MOLECULAR CELL

Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease

(2015) Lili Zhou et al.   Nature Reviews Nephrology

Implications of stemness-related signaling pathways in breast cancer response to therapy

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Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease

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AHNAK: The giant jack of all trades

(2014) T.A. Davis et al.   CELLULAR SIGNALLING

Wnt some lose some: transcriptional governance of stem cells by Wnt/ -catenin signaling

(2014) W.-H. Lien et al.   GENES & DEVELOPMENT

Periaxin and AHNAK Nucleoprotein 2 Form Intertwined Homodimers through Domain Swapping

(2014) Huijong Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ahnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway

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Wnt signaling in triple negative breast cancer is associated with metastasis

(2013) Nandini Dey et al.   BMC CANCER

Wnt signaling in stem and cancer stem cells

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Wnt/β-Catenin Signaling and Disease

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Dissecting the Heterogeneity of Triple-Negative Breast Cancer

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Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Structure of an Asymmetric Ternary Protein Complex Provides Insight for Membrane Interaction

(2012) Brian R. Dempsey et al.   STRUCTURE

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Metastasis and AKT activation

(2011) Meng Qiao et al.   CELL CYCLE

Self-regulated alternative splicing at the AHNAK locus

(2011) Antoine de Morrée et al.   FASEB JOURNAL

Pseudopodial Actin Dynamics Control Epithelial-Mesenchymal Transition in Metastatic Cancer Cells

(2010) Jay Shankar et al.   CANCER RESEARCH

Survival Outcomes for Patients with Metastatic Triple-Negative Breast Cancer: Implications for Clinical Practice and Trial Design

(2009) Farrah Kassam et al.   Clinical Breast Cancer

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Subtypes of Breast Cancer Show Preferential Site of Relapse

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Wnt Signaling Mediates Self-Organization and Axis Formation in Embryoid Bodies

(2008) Derk ten Berge et al.   Cell Stem Cell