A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability

Synthesis and structure–activity relationship of new cytotoxic agents targeting human glutathione-S-transferases

(2015) Dante Rotili et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A novel orally active water-soluble Inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

(2015) Anastasia De Luca et al.   Oncotarget

The fine-tuning of TRAF2–GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex

(2014) A De Luca et al.   Cell Death & Disease

New Insights into the Mechanism of JNK1 Inhibition by Glutathione Transferase P1-1

(2012) Anastasia De Luca et al.   BIOCHEMISTRY

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma

(2011) Lucio Tentori et al.   EUROPEAN JOURNAL OF CANCER

Fluorescence quenching and ligand binding: A critical discussion of a popular methodology

(2011) Marco van de Weert et al.   JOURNAL OF MOLECULAR STRUCTURE

Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines

(2011) Andrea Sau et al.   Molecular BioSystems

Glutathione transferases and development of new principles to overcome drug resistance

(2010) Andrea Sau et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma

(2009) Francesca Pellizzari Tregno et al.   EUROPEAN JOURNAL OF CANCER