Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?

5-Aminolevulinic acid-mediated photodynamic therapy for bladder cancer

(2017) Keiji Inoue   INTERNATIONAL JOURNAL OF UROLOGY

Acridine Orange/exosomes increase the delivery and the effectiveness of Acridine Orange in human melanoma cells: A new prototype for theranostics of tumors

(2017) Elisabetta Iessi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

(2017) Marco Bragagni et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma

(2017) Victoria Monge-Fuentes et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Metalloporphyrin-Encapsulated Biodegradable Nanosystems for Highly Efficient Magnetic Resonance Imaging-Guided Sonodynamic Cancer Therapy

(2017) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models

(2017) Rui Shi et al.   MOLECULES

Synthesis, spectral characterization, crystal structure, cytotoxicity and apoptosis—Inducing activity of two derivatives of 2-hydroxy-1,4-naphthaquinone

(2017) Kavitha Rani P.R. et al.   Photodiagnosis and Photodynamic Therapy

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

(2016) Stefano Fais et al.   ACS Nano

Indocyanine green delivery systems for tumour detection and treatments

(2016) Elena P. Porcu et al.   BIOTECHNOLOGY ADVANCES

Size-engineered biocompatible polymeric nanophotosensitizer for locoregional photodynamic therapy of cancer

(2016) Keunsoo Jeong et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Synthesis, Photophysical and Photochemical Properties of a Set of Silicon Phthalocyanines Bearing Anti-Inflammatory Groups

(2016) Belgin Şahin et al.   JOURNAL OF FLUORESCENCE

Delayed luminescence of erythrosine in biological tissue and photodynamic therapy dosimetry

(2016) S.N. Letuta et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy

(2016) Laura J. Broughton et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Plasmon-Induced Light Absorption of Phthalocyanine Layer in Hybrid Nanoparticles: Enhancement Factor and Effective Spectra

(2016) Anton V. Zasedatelev et al.   Journal of Physical Chemistry C

Generation of ROS mediated by mechanical waves (ultrasound) and its possible applications

(2016) Walter Duco et al.   METHODS

Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer

(2016) Yuko Nakamura et al.   MOLECULAR CANCER THERAPEUTICS

Photophysical Characterization and in Vitro Phototoxicity Evaluation of 5,10,15,20-Tetra(quinolin-2-yl)porphyrin as a Potential Sensitizer for Photodynamic Therapy

(2016) Letícia Costa et al.   MOLECULES

In Vitro Photodynamic Effect of Phycocyanin against Breast Cancer Cells

(2016) Subramaniyan Bharathiraja et al.   MOLECULES

Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

(2016) Xuying Ye et al.   MOLECULES

Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review

(2016) Giovana Calixto et al.   MOLECULES

Erratum: Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2016) Héctor Peinado et al.   NATURE MEDICINE

The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA)

(2016) Keiji Inoue et al.   Photodiagnosis and Photodynamic Therapy

Hypericin in the Dark: Foe or Ally in Photodynamic Therapy?

(2016) Veronika Huntosova et al.   Cancers

Exosomes: A Role for Naturally Occurring Nanovesicles in Cancer Growth, Diagnosis and Treatment

(2015) Akhil Srivastava et al.   CURRENT GENE THERAPY

Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications

(2015) Sweta Rani et al.   MOLECULAR THERAPY

Coumarin heterocyclic derivatives: chemical synthesis and biological activity

(2015) Fernanda G. Medina et al.   NATURAL PRODUCT REPORTS

Mesenchymal stem cell exosomes

(2015) Ruenn Chai Lai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Nanosystem Capable of Releasing a Photosensitizer Bioprecursor under Two-Photon Irradiation for Photodynamic Therapy

(2015) Hao Wu et al.   Advanced Science

Diketopyrrolopyrrole-Porphyrin Conjugates with High Two-Photon Absorption and Singlet Oxygen Generation for Two-Photon Photodynamic Therapy

(2014) Julie Schmitt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy

(2014) Leandro M. O. Lourenço et al.   CHEMICAL COMMUNICATIONS

Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy

(2014) Luis Muehlmann et al.   International Journal of Nanomedicine

Assessment of ALA-induced PpIX production in porcine skin pretreated with microneedles

(2014) Phamilla Gracielli Sousa Rodrigues et al.   Journal of Biophotonics

Dendritic Cell-Derived Exosomes as Immunotherapies in the Fight against Cancer

(2014) J. M. Pitt et al.   JOURNAL OF IMMUNOLOGY

Synthesis and Characterization of Glycoconjugated Porphyrin Triphenylamine Hybrids for Targeted Two-Photon Photodynamic Therapy

(2014) Fabien Hammerer et al.   JOURNAL OF ORGANIC CHEMISTRY

Synergistic effect of photodynamic therapy and cisplatin: A novel approach for cervical cancer

(2014) Laura Marise de Freitas et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Effect of methylene blue-mediated photodynamic therapy for treatment of basal cell carcinoma

(2014) Nevien A. Samy et al.   LASERS IN MEDICAL SCIENCE

Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin

(2014) Cristina Federici et al.   PLoS One

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

(2014) Britta Kleemann et al.   PLoS One

Nanoassembly of an amphiphilic cyclodextrin and Zn(ii)-phthalocyanine with the potential for photodynamic therapy of cancer

(2014) Claudia Conte et al.   RSC Advances

Extracellular Vesicles as Shuttles of Tumor Biomarkers and Anti-Tumor Drugs

(2014) Davide Zocco et al.   Frontiers in Oncology

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

Exosomes: the future of biomarkers in medicine

(2013) Francesca Properzi et al.   Biomarkers in Medicine

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century

(2013) Wing-Hin Lee et al.   Current Neuropharmacology

Photodynamic nanomedicine in the treatment of solid tumors: Perspectives and challenges

(2013) Alyssa Master et al.   JOURNAL OF CONTROLLED RELEASE

Phthalocyanine–Peptide Conjugates: Receptor-Targeting Bifunctional Agents for Imaging and Photodynamic Therapy

(2013) Elena Ranyuk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fractionated 5-aminolevulinic acid photodynamic therapy after partial debulking versus surgical excision for nodular basal cell carcinoma: A randomized controlled trial with at least 5-year follow-up

(2013) Marieke H. Roozeboom et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

(2013) Kevin Fitzgerald et al.   LANCET

Hypericin-photodynamic therapy leads to interleukin-6 secretion by HepG2 cells and their apoptosis via recruitment of BH3 interacting-domain death agonist and caspases

(2013) M Barathan et al.   Cell Death & Disease

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Exosomes: the ideal nanovectors for biodelivery

(2012) Stefano Fais et al.   BIOLOGICAL CHEMISTRY

Endocytosis at the nanoscale

(2012) Irene Canton et al.   CHEMICAL SOCIETY REVIEWS

Methylene blue photodynamic therapy in malignant melanoma decreases expression of proliferating cell nuclear antigen and heparanases

(2012) M. Wagner et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Translational Research of Photodynamic Therapy with Acridine Orange which Targets Cancer Acidity

(2012) Katsuyuki Kusuzaki et al.   CURRENT PHARMACEUTICAL DESIGN

Immune Surveillance Properties of Human NK Cell-Derived Exosomes

(2012) L. Lugini et al.   JOURNAL OF IMMUNOLOGY

Synthesis, photophysics and photochemistry of phthalocyanine-ɛ-polylysine conjugates in the presence of metal nanoparticles against Staphylococcus aureus

(2012) Nolwazi Nombona et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Previous illumination of a water soluble chlorine photosensitizer increases its cytotoxicity

(2012) J. C. Correa et al.   LASER PHYSICS

Evidence of 5-aminolevulinic acid (ALA) penetration increase due to microdrilling in soft tissue using femtosecond laser ablation

(2012) Gustavo Nicolodelli et al.   LASERS IN MEDICAL SCIENCE

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Conjugation of chlorin p 6 to histamine enhances its cellular uptake and phototoxicity in oral cancer cells

(2010) Arpana Parihar et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Photodynamic therapy with acridine orange in musculoskeletal sarcomas

(2010) T. Matsubara et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Transient species of several fluoroquinolones and their reactions with amino acids

(2010) Peng Zhang et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Clinical outcomes of minimally invasive surgery using acridine orange for musculoskeletal sarcomas around the forearm, compared with conventional limb salvage surgery after wide resection

(2010) Takao Matsubara et al.   JOURNAL OF SURGICAL ONCOLOGY

Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy

(2009) Lorena Rodriguez et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability

(2009) Matsubara   ONCOLOGY REPORTS

Photosensitized DNA Damage: The Case of Fluoroquinolones

(2009) Virginie Lhiaubet-Vallet et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

(2009) Sophie Viaud et al.   PLoS One

A new limb salvage surgery in cases of high-grade soft tissue sarcoma using photodynamic surgery, followed by photo- and radiodynamic therapy with acridine orange

(2008) Tomoki Nakamura et al.   JOURNAL OF SURGICAL ONCOLOGY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY