Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones

Hepatic Peroxisome Proliferator-Activated Receptor Gamma Signaling Contributes to Alcohol-Induced Hepatic Steatosis and Inflammation in Mice

(2016) Wenliang Zhang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity

(2016) Rainey E. Patterson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology

(2016) Karuna Rasineni et al.   BMC GASTROENTEROLOGY

Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

(2016) Samir Softic et al.   DIABETES

Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference

(2016) Signe Foghsgaard et al.   DIABETES CARE

Diagnosis of non-alcoholic fatty liver disease (NAFLD)

(2016) Hannele Yki-Järvinen   DIABETOLOGIA

Hepatic PPARγ Is Not Essential for the Rapid Development of Steatosis After Loss of Hepatic GH Signaling, in Adult Male Mice

(2016) Rhonda D. Kineman et al.   ENDOCRINOLOGY

Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice

(2016) Camella G. Wilson et al.   ENDOCRINOLOGY

DIAGNOSIS OF ENDOCRINE DISEASE: Prevalence of hypercortisolism in type 2 diabetes patients: a systematic review and meta-analysis

(2016) Charlotte Steffensen et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia

(2016) A. E. Junker et al.   JOURNAL OF INTERNAL MEDICINE

Curcumin inhibits lipolysis via suppression of ER stress in adipose tissue and prevents hepatic insulin resistance

(2016) Lulu Wang et al.   JOURNAL OF LIPID RESEARCH

Association between tamoxifen treatment and the development of different stages of nonalcoholic fatty liver disease among breast cancer patients

(2016) Hsiang-Ju Pan et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice

(2016) C. E. Geisler et al.   Nutrition & Metabolism

Investigating the role of cortisol and growth hormone in fatty liver development: fatty liver index in patients with pituitary adenomas

(2016) Matthias K. Auer et al.   Pituitary

The Relationship between Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Measured by Controlled Attenuation Parameter

(2016) Young Eun Chon et al.   YONSEI MEDICAL JOURNAL

Altered Skeletal Muscle Fatty Acid Handling in Subjects with Impaired Glucose Tolerance as Compared to Impaired Fasting Glucose

(2016) Gijs Goossens et al.   Nutrients

Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

(2016) Moina Hasni Ebou et al.   PLoS One

Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis

(2016) Hai Wang et al.   Scientific Reports

Pioglitazone for Hepatic Steatosis in HIV/Hepatitis C Virus Coinfection

(2015) Lindsay Matthews et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The Role of Lipin-1 in the Pathogenesis of Alcoholic Fatty Liver

(2015) Lijuan Bi et al.   ALCOHOL AND ALCOHOLISM

11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue

(2015) Ying Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effects of acute exercise on lipid content and dietary lipid uptake in liver and skeletal muscle of lean and diabetic rats

(2015) Sharon Janssens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Drug-induced fatty liver disease: An overview of pathogenesis and management

(2015) Sanjaya Satapathy et al.   Annals of Hepatology

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

(2015) Jose Cordoba-Chacon et al.   DIABETES

Prevalence of Nonalcoholic Fatty Liver Disease and Economy

(2015) Jin-Zhou Zhu et al.   DIGESTIVE DISEASES AND SCIENCES

Peripheral insulin resistance predicts liver damage in nondiabetic subjects with nonalcoholic fatty liver disease

(2015) Chiara Rosso et al.   HEPATOLOGY

Dyslipidemia in HIV Infected Children Receiving Highly Active Antiretroviral Therapy

(2015) Anirban Mandal et al.   INDIAN JOURNAL OF PEDIATRICS

Activation of OR1A1 suppresses PPAR-γ expression by inducing HES-1 in cultured hepatocytes

(2015) Chunyan Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

(2015) P Darkhal et al.   INTERNATIONAL JOURNAL OF OBESITY

Inhibition of mitochondrial β-oxidation by miR-107 promotes hepatic lipid accumulation and impairs glucose tolerance in vivo

(2015) H Bhatia et al.   INTERNATIONAL JOURNAL OF OBESITY

Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance

(2015) Pär Steneberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF21 and the late adaptive response to starvation in humans

(2015) Pouneh K. Fazeli et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis B Virus X Protein Induces Hepatic Steatosis by Enhancing the Expression of Liver Fatty Acid Binding Protein

(2015) Yun-li Wu et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Attenuates Mitochondrial Lipid β-Oxidation by Downregulating Mitochondrial Trifunctional-Protein Expression

(2015) Yutaka Amako et al.   JOURNAL OF VIROLOGY

Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice

(2015) Sandra Barbosa-da-Silva et al.   LIFE SCIENCES

Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans

(2015) Ville T. Männistö et al.   LIVER INTERNATIONAL

Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease

(2015) Cemal Nuri Ercin et al.   Metabolic Syndrome and Related Disorders

Acquired partial lipodystrophy is associated with increased risk for developing metabolic abnormalities

(2015) Baris Akinci et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure UponPparα Deficiency

(2015) Michal Pawlak et al.   MOLECULAR ENDOCRINOLOGY

Endocrine causes of nonalcoholic fatty liver disease

(2015) Laura Marino   WORLD JOURNAL OF GASTROENTEROLOGY

Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose

(2015) Alini Schultz et al.   Food & Function

Relevance of Sympathetic Nervous System Activation in Obesity and Metabolic Syndrome

(2015) Alicia A. Thorp et al.   Journal of Diabetes Research

Prevalence and factors associated with liver steatosis as measured by transient elastography with controlled attenuation parameter in HIV-infected patients

(2014) Juan Macías et al.   AIDS

Modulation of Fatty Acid and Bile Acid Metabolism By Peroxisome Proliferator-Activated ReceptorαProtects Against Alcoholic Liver Disease

(2014) Heng-Hong Li et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Insulin inhibits AMPK activity and phosphorylates AMPK Ser485/491 through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

(2014) Rudy J. Valentine et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Liver Glycogen Reduces Food Intake and Attenuates Obesity in a High-Fat Diet–Fed Mouse Model

(2014) Iliana López-Soldado et al.   DIABETES

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis

(2014) M. J. Armstrong et al.   DIABETES OBESITY & METABOLISM

Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance

(2014) Mark J. W. Hanssen et al.   DIABETOLOGIA

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

(2014) R. M. de Guia et al.   EMBO JOURNAL

FoxO6 Integrates Insulin Signaling With MTP for Regulating VLDL Production in the Liver

(2014) Dae Hyun Kim et al.   ENDOCRINOLOGY

Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-Deficient Diets

(2014) Ffolliott M. Fisher et al.   GASTROENTEROLOGY

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

(2014) Emilio P. Mottillo et al.   JOURNAL OF LIPID RESEARCH

High-fat diet from perilla oil induces insulin resistance despite lower serum lipids and increases hepatic fatty acid oxidation in rats

(2014) Tao Zhang et al.   Lipids in Health and Disease

Glucose-Induced Glucagon-Like Peptide 1 Secretion Is Deficient in Patients with Non-Alcoholic Fatty Liver Disease

(2014) Christine Bernsmeier et al.   PLoS One

Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

(2014) Holly A. Cyphert et al.   PLoS One

Clinical differences between alcoholic liver disease and nonalcoholic fatty liver disease

(2014) Nobuyuki Toshikuni   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial

(2014) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Prandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol

(2013) F. Shojaee-Moradie et al.   DIABETES

Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

(2013) M. K. Montgomery et al.   DIABETOLOGIA

Mechanisms in endocrinology: Non-alcoholic fatty liver disease in common endocrine disorders

(2013) Jonathan M Hazlehurst et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Selective hepatic insulin resistance in a murine model heterozygous for a mitochondrial trifunctional protein defect

(2013) R. Scott Rector et al.   HEPATOLOGY

Hepatic Adverse Effects of Fructose Consumption Independent of Overweight/Obesity

(2013) Alini Schultz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The liver diseases of lipodystrophy: The long-term effect of leptin treatment

(2013) Elika Safar Zadeh et al.   JOURNAL OF HEPATOLOGY

CD36-deficient mice are resistant to alcohol- and high-carbohydrate-induced hepatic steatosis

(2013) Robin D. Clugston et al.   JOURNAL OF LIPID RESEARCH

Quantitative Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet (HFD) Diabetic Mice

(2013) Yurong Guo et al.   MOLECULAR & CELLULAR PROTEOMICS

Hepatic energy metabolism in human diabetes mellitus, obesity and non-alcoholic fatty liver disease

(2013) Chrysi Koliaki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metformin trims fats to restore insulin sensitivity

(2013) Reuben J Shaw   NATURE MEDICINE

Keap1-Knockdown Decreases Fasting-Induced Fatty Liver via Altered Lipid Metabolism and Decreased Fatty Acid Mobilization from Adipose Tissue

(2013) Jialin Xu et al.   PLoS One

HES1 Is a Master Regulator of Glucocorticoid Receptor-Dependent Gene Expression

(2013) J. R. Revollo et al.   Science Signaling

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

(2013) Leah Eissing et al.   Nature Communications

Partial Inhibition of Adipose Tissue Lipolysis Improves Glucose Metabolism and Insulin Sensitivity Without Alteration of Fat Mass

(2013) Amandine Girousse et al.   PLOS BIOLOGY

Consumption of a high-fat diet rapidly exacerbates the development of fatty liver disease that occurs with chronically elevated glucocorticoids

(2012) Anna M. D'souza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity

(2012) Zhen-Yu Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis

(2012) Paul A. Grimsrud et al.   Cell Metabolism

Hepatic Insulin Signaling Is Required for Obesity-Dependent Expression of SREBP-1c mRNA but Not for Feeding-Dependent Expression

(2012) Joel T. Haas et al.   Cell Metabolism

Fatty liver and insulin resistance in children with hypobetalipoproteinemia: the importance of aetiology

(2012) Claudia Della Corte et al.   CLINICAL ENDOCRINOLOGY

A Role for Adipose Tissue De Novo Lipogenesis in Glucose Homeostasis During Catch-up Growth: A Randle Cycle Favoring Fat Storage

(2012) H. Marcelino et al.   DIABETES

In vivo postprandial lipid partitioning in liver and skeletal muscle in prediabetic and diabetic rats

(2012) R. A. M. Jonkers et al.   DIABETOLOGIA

Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy

(2012) H. Nishizawa et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

FoxO1 Inhibits Sterol Regulatory Element-binding Protein-1c (SREBP-1c) Gene Expression via Transcription Factors Sp1 and SREBP-1c

(2012) Xiong Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired Crosstalk between Pulsatile Insulin and Glucagon Secretion in Prediabetic Individuals

(2012) Stefan Rohrer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

A Switch in Hepatic Cortisol Metabolism across the Spectrum of Non Alcoholic Fatty Liver Disease

(2012) Adeeba Ahmed et al.   PLoS One

Association between Serum Growth Hormone Levels and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study

(2012) Lei Xu et al.   PLoS One

Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation

(2012) Yukari Ido-Kitamura et al.   PLoS One

Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion

(2012) G. A. Kyriazis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonalcoholic Fatty Liver Disease and HIV Infection

(2012) Anaïs Vallet-Pichard et al.   SEMINARS IN LIVER DISEASE

Insulin-sensitive obesity in humans – a ‘favorable fat’ phenotype?

(2012) D. Samocha-Bonet et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Non-alcoholic fatty liver disease

(2012) Ana C. TUYAMA et al.   Journal of Diabetes

High-sucrose diet increases ROS generation, FFA accumulation, UCP2 level, and proton leak in liver mitochondria

(2011) Angélica Ruiz-Ramírez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis

(2011) Jiyun Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

(2011) Y. Lee et al.   DIABETES

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

(2011) Eva Morán-Salvador et al.   FASEB JOURNAL

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Regulation of hepatic lipin-1 by ethanol: Role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice

(2011) Ming Hu et al.   HEPATOLOGY

Up-Regulation of PPAR-γ mRNA Expression in the Liver of Obese Patients: an Additional Reinforcing Lipogenic Mechanism to SREBP-1c Induction

(2011) Paulina Pettinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Peroxisome proliferator-activated receptor-α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis

(2011) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism

(2011) Guoping Li et al.   JOURNAL OF LIPID RESEARCH

The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men

(2011) Jeffrey D. Browning et al.   JOURNAL OF LIPID RESEARCH

Regulation of Lipogenesis by Glucocorticoids and Insulin in Human Adipose Tissue

(2011) Laura L. Gathercole et al.   PLoS One

β-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle

(2010) Takashi Yamada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet

(2010) Nishanth E. Sunny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo

(2010) Eric D. Berglund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy?

(2010) Chris N. Goulbourne et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Non-alcoholic and alcoholic Fatty Liver Disease - two Diseases of Affluence associated with the Metabolic Syndrome and Type 2 Diabetes: the FIN-D2D Survey

(2010) Anna Kotronen et al.   BMC PUBLIC HEALTH

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

Lipotoxicity on the Basis of Metabolic Syndrome and Lipodystrophy in HIV-1-Infected Patients Under Antiretroviral Treatment

(2010) Marta Giralt et al.   CURRENT PHARMACEUTICAL DESIGN

Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

(2010) J. Hoeks et al.   DIABETES

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Dissociation Between Intrahepatic Triglyceride Content and Insulin Resistance in Familial Hypobetalipoproteinemia

(2010) Anastassia Amaro et al.   GASTROENTEROLOGY

Glucose Suppression of Glucagon Secretion

(2010) Sylvain J. Le Marchand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-activated Receptor α Is Responsible for the Up-regulation of Hepatic Glucose-6-phosphatase Gene Expression in Fasting anddb/dbMice

(2010) Seung-Soon Im et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Postprandial hyperinsulinemia is universal in non-diabetic patients with nonalcoholic fatty liver disease

(2010) Jayani Manchanayake et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Liver fatty acid-binding protein and obesity

(2010) Barbara P. Atshaves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Increased adipose tissue lipolysis after a 2-week high-fat diet in sedentary overweight/obese men

(2010) Harold R. Howe et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Peroxisome proliferator activated receptor α (PPARα) and PPAR gamma coactivator (PGC-1α) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements

(2010) Shulan Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus

(2009) Hyun-Young Koo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis

(2009) Koji Fujita et al.   HEPATOLOGY

Hepatic energy state is regulated by glucagon receptor signaling in mice

(2009) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle

(2009) Zhengshan Zhao et al.   LIFE SCIENCES

Betaine administration corrects ethanol-induced defective VLDL secretion

(2009) Kusum K. Kharbanda et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Direct Effect of Glucocorticoids on Lipolysis in Adipocytes

(2009) Chong Xu et al.   MOLECULAR ENDOCRINOLOGY

Relationship Between Body Fat Mass and Free Fatty Acid Kinetics in Men and Women

(2009) Bettina Mittendorfer et al.   Obesity

Lipoprotein Lipase Expression in Livers of Morbidly Obese Patients Could be Responsible for Liver Steatosis

(2009) Eva Pardina et al.   OBESITY SURGERY

De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis

(2009) Mohamed Sabry Hamza et al.   PLoS One

Mitochondrial trifunctional protein defects: Clinical implications and therapeutic approaches☆

(2008) R. Scott Rector et al.   ADVANCED DRUG DELIVERY REVIEWS

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

(2008) Maja Stefanovic-Racic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification and Characterization of Metabolically Benign Obesity in Humans

(2008) Norbert Stefan   ARCHIVES OF INTERNAL MEDICINE

The Glucocorticoid Receptor Controls Hepatic Dyslipidemia through Hes1

(2008) Ulrike Lemke et al.   Cell Metabolism

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity

(2008) Yu Takahashi et al.   JOURNAL OF LIPID RESEARCH

Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically

(2008) Boripont Manmontri et al.   JOURNAL OF LIPID RESEARCH

Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

(2008) Kaori Minehira et al.   JOURNAL OF LIPID RESEARCH