期刊
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
卷 41, 期 6, 页码 931-936出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RCT.0000000000000617
关键词
dual-energy CT; spectral CT; multidetector computed tomography; dental artifact; noise; head and neck cancer; head and neck squamous cell carcinoma; phantom study; iodine maps; virtual monochromatic images
资金
- Fonds de recherche du Quebec - Sante (FRQS) [26856]
Objective Dual-energy computed tomography high energy virtual monochromatic images (VMIs) can reduce artifact but suppress iodine attenuation in enhancing tumor. We investigated this trade-off to identify VMI(s) that strike the best balance between iodine detection and artifact reduction. Methods The study was performed using an Alderson radiation therapy phantom. Different iodine solutions (based on estimated tumor iodine content in situ using dual-energy computed tomography material decomposition) and different dental fillings were investigated. Spectral attenuation curves and quality index (QI: 1/SD) were evaluated. Results The relationship between iodine attenuation and QI depends on artifact severity and iodine concentration. For low to average concentration solutions degraded by mild to moderate artifact, the iodine attenuation and QI curves crossed at 95 keV. Conclusions High energy VMIs less than 100 keV can achieve modest artifact reduction while preserving sufficient iodine attenuation and could represent a useful additional reconstruction for evaluation of head and neck cancer.
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