期刊
DERMATOLOGIC CLINICS
卷 33, 期 3, 页码 361-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2015.03.004
关键词
Rheumatoid nodules; Accelerated nodulosis; Palisading macrophages; Benign nodulosis; Methotrexate; Rheumatoid arthritis; Pulmonary rheumatoid nodules
类别
Rheumatoid nodules are a common manifestation of rheumatoid arthritis. These lesions are often easily identified based on typical diagnostic features and characteristic locations. When biopsied, nodules have a characteristic histologic appearance. Uncommonly, rheumatoid nodules can occur in systemic locations. There is no evidence that systemic therapy treats underlying rheumatoid nodules. Paradoxically, methotrexate and possibly tumor necrosis factor inhibitors can increase nodule development. Treatment of rheumatoid nodules is often not necessary, unless patients are experiencing pain or there is interference of mechanical function. This review outlines the available data on and associations of rheumatoid nodules.
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