Article
Agricultural Engineering
Qihui Dong, Jun Cao, Rong Wu, Tingting Shi, Wen Zhang, Fuliang Cao, Guibin Wang, Erzheng Su
Summary: A liquid-liquid microextraction method using a hydrophobic deep eutectic solvent (DES) was developed to efficiently remove ginkgolic acids (GAs) from Ginkgo biloba leaves crude extract, with optimized conditions achieving high removal rates and retention levels. Scaling up the removal operation volume by 100 times did not decrease the removal rate of GAs, indicating the potential of hydrophobic DESs for green GAs removal in standardized EGb production.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Agricultural Engineering
Qihui Dong, Jun Cao, Luyao Chen, Jiarui Cao, Huimin Wang, Fuliang Cao, Erzheng Su
Summary: Botanical natural bioactive ingredients are difficult to purify due to their complicated composition and structure, and are usually utilized in the form of phytocomplex, which refers to a mixture of multiple bioactive ingredients. Using biocompatible solvents as delivery solvents is a simple, versatile, and scalable method to improve the solubility of phytocomplex. In this work, the extract of Ginkgo biloba leaves (EGb) was chosen as the model of the phytocomplex to systematically investigate the potential of natural deep eutectic solvents (NADESs) as solubilizers.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Applied
Tong Wang, Qing Wang, Qing Guo, Ping Li, Hua Yang
Summary: A novel method combining ultrasound-assisted extraction and high-speed countercurrent chromatography (HSCCC) separation using hydrophobic deep eutectic solvent (DES) was proposed for the extraction and recovery of hydrophobic compounds. Results showed that hydrophobic DESs are more effective in extracting hydrophobic compounds compared to hydrophilic DESs and traditional solvents, and can be used as HSCCC separation solvents effectively. The diverse components and combinations of DESs provide endless selective space for hydrophobic compounds in the HSCCC separation process.
Article
Chemistry, Physical
Victor Hernandez-Serrano, Jose Munoz-Embid, Fernando Bergua, Carlos Lafuente, Manuela Artal
Summary: One of the basic principles of green chemistry is to find less harmful alternative solvents. This study provides density data for two hydrophilic deep eutectic solvents (choline chloride + ethylene glycol or glycerol) and two hydrophobic eutectic solvents (camphor + thymol or menthol) at various pressures and temperatures. The Tait equation of state and the PC-SAFT equation of state are used to correlate the data and calculate derived properties. The results show that the hydrophilic solvents are more compact and exhibit abnormal thermal behavior.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Maninder Meenu, Vasudha Bansal, Sudha Rana, Nitya Sharma, Vinod Kumar, Vaishali Arora, Monika Garg
Summary: Anthocyanins are extracted using alternative solvents such as ionic liquids, deep eutectic solvents, and natural deep eutectic solvents, which are more environmentally friendly and efficient compared to conventional solvents. Acid-based deep eutectic solvents with 20-30% water content showed the highest anthocyanin extraction yield. Ultrasonic-assisted extraction was the most common and efficient method, and DES-based extracts exhibited the highest stability and antioxidant activity. Fruits and their by-products are the most commonly used samples, while cereal and legumes are less explored.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Green & Sustainable Science & Technology
Yuxuan Zhang, Qi Qiao, Usman L. Abbas, Jun Liu, Yi Zheng, Christopher Jones, Qing Shao, Jian Shi
Summary: Solvent innovation is crucial for enhancing the sustainability of chemical processes. Deep eutectic solvents (DESs) have emerged as environmentally friendly alternatives to toxic and volatile solvents. In this study, hydrophobic DESs derived from lignin were synthesized and their physicochemical properties were characterized. The DESs showed promise as green solvents due to their low viscosity and environmentally friendly constituents. Liquid-liquid extraction experiments revealed high extraction efficiency for biofuel fermentation products using specific DES compositions. Molecular dynamic simulations provided insights into the DES molecular interactions and formation mechanism. This work highlights the potential of lignin-derived hydrophobic DESs as sustainable extraction media.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Engineering, Environmental
Ke Xue, Dingchao Fan, Xiang Wang, Zihao Dong, Zhaoyou Zhu, Peizhe Cui, Fanqing Meng, Yinglong Wang, Jianguang Qi
Summary: Due to the increasing scarcity of lithium resources, the recovery of lithium ions from water resources is an urgent problem. This paper proposes an environmentally friendly liquid-liquid extraction (LLE) process for lithium ion recovery. Nine hydrophobic deep eutectic solvents (HDESs) were formed using menthol (DLM) as a hydrogen bond acceptor (HBA) and octanoic acid, decanoic acid, and lauric acid (LA) as hydrogen bond donors (HBDs). HDESs synthesized with DLM and LA showed the best effect and were selected for the lithium extraction experiment. The single extraction efficiency of lithium ions was 80.69%, with optimized parameters such as rotational speed, equilibrium time, pH, molar ratio, and initial concentration.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Engineering, Environmental
Chun-Chi Chen, Yen-Hui Huang, Shih-Min Hung, Chiaying Chen, Chi-Wen Lin, Hsi-Hsien Yang
Summary: This study evaluated the feasibility of capturing VOCs from exhaust using hydrophobic deep eutectic solvents (DESs), and found that DESs with fatty acids containing long alkyl chains achieved high absorption capacity. The hydrophobic interactions in fatty acid eutectics were critical for improving VOC absorption ability.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Environmental
Chun-Chi Chen, Yen -Hui Huang, Jia-Yu Fang
Summary: The study demonstrates that hydrophobic deep eutectic solvents (DESs) are efficient in eliminating hydrophilic VOCs due to their high absorption capacity and favorable gas-to-liquid mass transfer. Among the DESs explored, the one containing thymol and decanoic acid in a 1:1 molar ratio exhibits the highest acetone absorption capacity, showing the key role of hydrogen bonding interaction in achieving superior solubility of acetone in DESs. The absorbed acetone can be easily removed from the DESs, making the process economically and ecologically beneficial for hydrophilic VOC elimination.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Seif A. Abouheif, Shaimaa M. Sallam, Samah M. El Sohafy, Fahima F. Kassem, Eman Shawky
Summary: In this study, a green extraction method was developed to maximize the yield of terpene lactones and minimize that of ginkgolic acids from Ginkgo biloba L. leaves. The highest extraction yields of total ginkgolides were obtained using DES2 (Choline chloride, ascorbic acid), while significantly lower extraction amounts of ginkgolic acids were obtained compared to conventional solvents. Optimization experiments showed that water percentage had the highest influence on the extraction yield of ginkgolides, followed by ultrasonication temperature, while ultrasonication temperature had a stronger influence on the extraction yield of ginkgolic acids. The optimum conditions for extraction were determined to be an ultrasonication time of 36.63 min, a temperature of 55.77 °C, and a water content of 33.66% v/v.
MICROCHEMICAL JOURNAL
(2022)
Article
Engineering, Chemical
Raquel Canadas, Maria Gonzalez-Miquel, Emilio J. Gonzalez, Ismael Diaz, Manuel Rodriguez
Summary: This study aims to recover phenolic compounds derived from wine using hydrophobic eutectic solvents (HESs), achieving satisfactory results through the optimization of experimental conditions.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Physical
Shima Barakan, Valeh Aghazadeh
Summary: This study evaluates the potential of hydrophobic deep eutectic solvents (DESs) as an eco-friendly solvent for extracting rhenium (Re). The selective transfer of Re from aqueous and pressure oxidative leaching solutions was investigated using a mixture of fatty acid and quaternary ammonium salt. The extraction potential of hydrophobic-DES was evaluated through various tests and an optimum condition for Re separation was found. Another aspect of the study focused on the toxicology of hydrophobic-DES, which was found to have low toxicity according to the MTT method.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Analytical
Yu Xu, Ang Li, Song Xue, Sihui Ding, Qi Zhang
Summary: This study demonstrates the use of hydrophobic deep eutectic solvents (HDESs) in capillary electrophoresis (CE) for chiral separations. The HDES N8881Cl:OctA can form nano-sized microdroplets in CE background electrolyte solutions and acts as a new type of pseudo-stationary phase (PSP) exhibiting hydrophobic effects. The presence of N8881Cl:OctA significantly improves the enantioresolutions of model drugs with various cyclodextrin (CD)-type chiral selectors, and the migration time of enantiomers can be reduced using an anionic CD.
Article
Chemistry, Multidisciplinary
Andrew J. Peloquin, Jena M. McCollum, Colin D. McMillen, William T. Pennington
Summary: This article discusses a new deep eutectic solvent based on halogen bonding, which is different from the majority of DESs that rely on ionic components. The newly developed deep eutectic solvent remains in liquid form, with a eutectic melting temperature at different 1,3-dithiane mole fractions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Engineering, Chemical
Tomas Hlozek, Tereza Bosakova, Zuzana Bosakova, Petr Tuma
Summary: Effective elimination of estrogens from water sources and wastewater is crucial. Hydrophobic eutectic solvents (ES) show high extraction efficiency, with menthol and octanoic acid in a 1:1 ratio being the most effective for all estrogens.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jun Cao, Rong Wu, Qihui Dong, Linguo Zhao, Fuliang Cao, Erzheng Su
Article
Biotechnology & Applied Microbiology
Jianguo Zhang, Hongli Mao, Mengla Li, Erzheng Su
BIOCHEMICAL ENGINEERING JOURNAL
(2019)
Article
Chemistry, Analytical
Lu Han, Jingyi Zhu, Xia Fan, Chong Zhang, Kang Tu, Jing Peng, Jiahong Wang, Leiqing Pan
Article
Agriculture, Multidisciplinary
Wen Zhang, Minmin Zou, Rong Wu, Huijuan Jiang, Fuliang Cao, Erzheng Su
Summary: The study developed a method combining resin adsorption and endogenous enzymatic hydrolysis to remove ginkgotoxin from Ginkgo seed powder, preserving its main nutritional and functional components to the maximum extent without altering its main characteristics. This approach proved to be relatively simple and efficient.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Food Science & Technology
Jin-Peng Zhu, Hao Gong, Cai-E Wu, Gong-Jian Fan, Ting-Ting Li, Jia-Hong Wang
Summary: This study investigated the extraction of the toxic substance MPN from Ginkgo biloba seeds and its toxic effects on human gastric epithelial cells. Results indicated that MPN inhibited cell proliferation, arrested the cell cycle, affected the cell nucleus, and induced apoptosis in GES-1 cells. Furthermore, MPN was found to reduce mitochondrial membrane potential and increase apoptotic protein expression levels in GES-1 cells, suggesting its potential to induce apoptosis and toxicity in the human body.
Article
Food Science & Technology
Li Fang, Kangli Wei, Li Feng, Kang Tu, Jing Peng, Jiahong Wang, Leiqing Pan
Review
Food Science & Technology
Zilun Lei, Xianqiang Chen, Fuliang Cao, Qirong Guo, Jiahong Wang
Summary: Goji leaves, traditionally used in Chinese medicine for nourishing kidneys and enhancing eyesight, are currently mostly discarded. The nutritional composition of Goji leaves is similar to that of the berries, with some components even more abundant in the former. Researchers propose potential applications of Goji leaves in the food industry and advocate for further research.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Lihu Zhang, Chunyi Zhu, Xiaoqing Liu, Erzheng Su, Fuliang Cao, Linguo Zhao
Summary: The study found that Ginkgo biloba extract has antioxidant properties that are related to apoptosis, proliferation, lipid metabolism, cell differentiation, and immune response. The four typical components of Ginkgo biloba extract, ginkgo flavone, ginkgolide, procyanidins, and organic acids, have different antioxidant capacities and exhibit synergistic effects. Molecular docking and network pharmacology were used to predict the biological functions and signaling pathways involved in the antioxidant activities of Ginkgo biloba extract.
Article
Food Science & Technology
Qiang Liu, Shaoxia Chen, Dandan Zhou, Chao Ding, Jiahong Wang, Hongsheng Zhou, Kang Tu, Leiqing Pan, Pengxia Li
Summary: This study demonstrates the use of FT-NIR spectroscopy for quality assessment of mini-Chinese cabbage with nanopackaging during storage, with prediction models developed for various quality attributes using PLSR and support vector machine. Different preprocessing methods were compared for their performance, showing that SNV-PLSR model had the best prediction performance for weight loss rate. SVC was able to predict freshness levels with high accuracy in mini-Chinese cabbage. The results suggest the potential implementation of FT-NIR spectroscopy for comprehensive assessments of internal and external quality attributes of mini-Chinese cabbage with nanopacking.
Article
Microbiology
Ming Gong, Tianyu Huang, Yan Li, Jinxin Li, Lihua Tang, Erzheng Su, Gen Zou, Dapeng Bao
Summary: This study conducted a comprehensive multi-omics analysis to elucidate the molecular mechanism of low-temperature fruiting after a long postripening (LFLP) in Hypsizygus marmoreus. The results revealed that the changes in pH were closely correlated with variations in citrate and arginine. By enhancing the enzyme activity of the arginine synthesis branch pathway in the citrate cycle, the levels of citric acid and arginine were synergistically increased, providing enriched materials for amino acid biosynthesis. Furthermore, GCN2 mediated metabolic adaptation through enhanced protein translation. Exogenously added citric acid and arginine shortened the postripening period and increased the yield.
Article
Environmental Sciences
Zilun Lei, Xianqiang Chen, Fuliang Cao, Qirong Guo, Jiahong Wang
Summary: This study focuses on the utilization of Lycium barbarum leaves (LBL), an agro-industrial residue, to extract valuable resources through the production of enzyme cocktails and enzymatic hydrolysis. The results showed that high xylanase activity enzyme cocktails can be produced from a soil-derived fungal strain, and 86.57% of total reducing sugars from LBL can be released through hydrolysis. This study provides valuable references for the exploitation of LBL resources and the utilization of other agro-industrial residues.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Chemistry, Analytical
Mengyu Miao, Xianqiang Chen, Zhenghang Wu, Jiameng Liu, Chenyu Xu, Zhuan Zhang, Jiahong Wang
Summary: By utilizing ultrasound-assisted extraction, this study successfully extracted flavonoids from Xanthoceras sorbifolium Bunge leaves. The optimal conditions of ethanol concentration, liquid:solid ratio, and ultrasonic power were determined to achieve the highest yield of total flavonoids. Furthermore, the chemical structures of these compounds were identified using UPLC-MS/MS and HPLC techniques.
JOURNAL OF AOAC INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Lihu Zhang, Xianying Fang, Jihu Sun, Erzheng Su, Fuliang Cao, Linguo Zhao
Summary: There are differences in anti-inflammatory activities among four typical components in EGB (extracts of ginkgo biloba leaves), with a synergistic relationship. The order of inhibiting NO-release ability is OA > GF > OPC > G. Ginkgolide (G), proanthocyanidins (OPC), and organic acids (OA) all have synergistic effects on ginkgo flavonoids (GF). GF:OA (1:9) shows the strongest synergy. The anti-inflammatory mechanism of the compound affects the expression of p-JNK, p-P38, and p-ERK1/2 proteins by inhibiting the expression of iNOS and COX2 genes on NFKB and MAPK pathways. This provides a research basis for developing anti-inflammatory deep-processing products of EGB.
Article
Food Science & Technology
Xianqiang Chen, Zilun Lei, Fuliang Cao, Qirong Guo, Jiahong Wang
Summary: In this study, the extraction, purification, identification, and biological activities of saponins from Xanthoceras sorbifolium Bunge leaves were investigated. The results showed that the saponins possessed good scavenging activity on DPPH and ABTS, and exhibited inhibitory effects on E. coli and S. aureus. This study provides a theoretical basis for the development and utilization of the by-products from Xanthoceras sorbifolium Bunge leaves.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Biotechnology & Applied Microbiology
Bolin Chen, Fang Zhang, Zhifan Li, Yaping Hu, Qirong Guo, Erzheng Su, Fuliang Cao
Summary: Ginkgo biloba seed (GBS) is a rich source of nutrients and can be used for fermentation and brewing. This study optimized the fermentation process of GBS to produce ginkgo wine using different fermentation starters. The results showed that the composition of the wine was significantly impacted by the choice of fermentation starter, with the yeast group having higher sugar content and better evaluation scores. The yeast-fermented ginkgo wine also had higher antioxidant capacity compared to the Jiuqu group.
FERMENTATION-BASEL
(2023)
Article
Green & Sustainable Science & Technology
Lars odegaard Bentsen, Narada Dilp Warakagoda, Roy Stenbro, Paal Engelstad
Summary: This study investigates uncertainty modeling in wind power forecasting using different parametric and non-parametric methods. Johnson's SU distribution is found to outperform Gaussian distributions in predicting wind power. This research contributes to the literature by introducing Johnson's SU distribution as a candidate for probabilistic wind forecasting.
JOURNAL OF CLEANER PRODUCTION
(2024)
Article
Green & Sustainable Science & Technology
Xing Liu, Qiuchen Wang, Yunhao Wen, Long Li, Xinfang Zhang, Yi Wang
Summary: This study analyzes the characteristics of process parameters in three lean gas ethane recovery processes and establishes a prediction and multiobjective optimization model for ethane recovery and system energy consumption. A new method for comparing ethane recovery processes for lean gas is proposed, and the addition of extra coolers improves the ethane recovery. The support vector regression model based on grey wolf optimization demonstrates the highest prediction accuracy, and the multiobjective multiverse optimization algorithm shows the best optimization performance and diversity in the solutions.
JOURNAL OF CLEANER PRODUCTION
(2024)
Article
Green & Sustainable Science & Technology
Cairong Song, Haidong Yang, Xian-Bing Meng, Pan Yang, Jianyang Cai, Hao Bao, Kangkang Xu
Summary: The paper proposes a novel deep learning-based prediction framework, aTCN-LSTM, for accurate cooling load predictions. The framework utilizes a gate-controlled multi-head temporal convolutional network and a sparse probabilistic self-attention mechanism with a bidirectional long short-term memory network to capture both temporal and long-term dependencies in the cooling load sequences. Experimental results demonstrate the effectiveness and superiority of the proposed method, which can serve as an effective guide for HVAC chiller scheduling and demand management initiatives.
JOURNAL OF CLEANER PRODUCTION
(2024)
Article
Green & Sustainable Science & Technology
Zhe Chen, Xiaojing Li, Xianli Xia, Jizhou Zhang
Summary: This study uses survey data from the Loess Plateau in China to evaluate the impact of social interaction on the adoption of soil and water conservation (SWC) technology by farmers. The study finds that social interaction increases the likelihood of farmers adopting SWC, and internet use moderates this effect. The positive impact of social interaction on SWC adoption is more pronounced for farmers in larger villages and those who join cooperative societies.
JOURNAL OF CLEANER PRODUCTION
(2024)
Article
Green & Sustainable Science & Technology
Chenghua Zhang, Yunfei Yan, Kaiming Shen, Zongguo Xue, Jingxiang You, Yonghong Wu, Ziqiang He
Summary: This paper reports a novel method that significantly improves combustion performance, including heat transfer enhancement under steady-state conditions and adaptive stable flame regulation under velocity sudden increase.
JOURNAL OF CLEANER PRODUCTION
(2024)
