Article
Clinical Neurology
Jakob Roetner, Jessica Van Doren, Janina Maschke, Louisa Kulke, Constanza A. Pontones, Peter W. Fasching, Matthias Beckmann, Bernd Lenz, Oliver H. Kratz, Gunther Moll, Johannes Kornhuber, Anna Eichler, IMAC Mind Consortium
Summary: This study investigated the long-term effects of low/moderate prenatal alcohol exposure (PAE) on neurocognitive development in adolescence. The findings showed that PAE had negative effects on attentional resource recruitment, IQ scores, and cognitive function in both childhood and adolescence. These results suggest the importance of early identification and treatment of at-risk children and the need for more thorough screening of alcohol consumption during pregnancy.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Neurosciences
Janina Maschke, Jakob Roetner, Tamme W. Goecke, Peter A. Fasching, Matthias W. Beckmann, Oliver Kratz, Gunther H. Moll, Bernd Lenz, Johannes Kornhuber, Anna Eichler
Summary: The study found associations between prenatal alcohol exposure (PAE) and facial malformation, as well as cognitive development in adolescents. Meconium ethyl glucoronide (EtG) was a better predictor of effects than maternal self-reports. This highlights the importance of early detection and intervention for children exposed to alcohol in utero.
Article
Biochemical Research Methods
Mateusz Kacper Wozniak, Laura Banaszkiewicz, Justyna Aszyk, Marek Wiergowski, Iwona Janczewska, Jolanta Wierzba, Agata Kot-Wasik, Marek Biziuk
Summary: This study developed a method for the simultaneous extraction of FAEEs, EtG, and EtS from one meconium aliquot, demonstrating sensitivity, accuracy, efficiency, and the potential for reduced organic solvent usage compared to existing methods.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Psychology, Developmental
Nicoletta Adamo, Giorgia Michelini, Celeste H. M. Cheung, Jan K. Buitelaar, Philip Asherson, Fruhling Rijsdijk, Jonna Kuntsi
Summary: Individuals with ADHD showed significantly elevated anxiety symptoms compared with controls. Only commission errors on a Continuous Performance Test (measuring response inhibition) were significantly associated with anxiety symptoms and only among controls, with the ADHD-control difference in this measure remaining significant. This investigation suggests limited malleability of these impairments in individuals with ADHD irrespective of their levels of anxiety, based on a wide range of cognitive, electrophysiological, and electrodermal measures.
JOURNAL OF ATTENTION DISORDERS
(2021)
Article
Psychiatry
Oliver Grimm, Daan van Rooij, Asya Tshagharyan, Dilek Yildiz, Jan Leonards, Ahmed Elgohary, Jan Buitelaar, Andreas Reif
Summary: In this study, MRI scans and reward system testing revealed that ADHD patients with comorbid disorders may have less intrastriatal connectivity, indicating that greater comorbidity severity could result in impaired reward and decision-making abilities in patients.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Luis M. Garcia-Marin, Adrian Campos, Gabriel Cuellar-Partida, Sarah E. Medland, Scott H. Kollins, Miguel E. Renteria
Summary: ADHD is a complex psychiatric and neurodevelopmental disorder that develops during childhood and spans into adulthood. Research findings indicate that genetic variants associated with iron deficiency anemia, obesity, type 2 diabetes, and other factors increase the risk of developing ADHD in children, while genetic factors related to social support and interactive activities have a protective effect against ADHD.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Elham Ghasemi, Mansour Ebrahimi, Esmaeil Ebrahimie
Summary: Accurate diagnosis of ADHD is challenging, but automatic diagnosis using machine learning analysis of brain signals is receiving increased attention. This study developed a model to accurately discriminate between ADHD patients and healthy controls by pattern discovery and feature combination. The results showed that complementary features can significantly improve the performance of predictive models.
COGNITIVE NEURODYNAMICS
(2022)
Article
Neurosciences
Anne B. Arnett, Virginia Peisch, April R. Levin
Summary: This study investigates the associations between aperiodic spectral slope and three aspects of neurocognition: event-related potential (ERP) amplitudes, cognitive load, and task performance. The results suggest that background oscillatory activity is dynamic and changes in response to varying levels of task relevance and increasing cognitive load. Furthermore, children with ADHD show reduced aperiodic dynamics in addition to attenuated ERP amplitudes.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Engineering, Biomedical
Cheng Wang, Xin Wang, Xiaobei Jing, Hiroshi Yokoi, Weimin Huang, Mingxing Zhu, Shixiong Chen, Guanglin Li
Summary: The study proposes a method using the CNN-LSTM model to effectively identify children with ADHD and its subtypes. The visualized features extracted by this model can better explain the differences in ERP response among different groups, providing more reliable neural biomarkers for accurate diagnosis in clinics.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Psychology, Multidisciplinary
Morgan M. Grotewiel, Megan E. Crenshaw, Amelia Dorsey, Elizabeth Street
Summary: Hyperfocus and flow are intense concentration experiences associated with reduced perception of irrelevant stimuli and improved task performance. Hyperfocus has been historically seen as a symptom of ADHD, autism, or schizophrenia, while flow is regarded as an enjoyable experience in positive psychology. Recent studies suggest that hyperfocus and flow may be the same phenomenon viewed from different perspectives.
CURRENT PSYCHOLOGY
(2023)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Medicine, General & Internal
Nadia Ali, Amanda Caceres, Eric W. Hall, Dawn Laney
Summary: This pilot study compared reported symptoms of attention-deficit/hyperactivity in adults with Fabry disease with normative control data, finding a higher prevalence of symptoms in Fabry disease patients. The study suggests that attention difficulties in Fabry disease patients are not solely explained by ADHD. Patients reporting symptoms were also more likely to report difficulties in adaptive functioning.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Erica D. Musser, Stephanie S. J. Morris, Kathleen Feeney, Rosario Pintos Lobo, Edward F. Ester
Summary: Inattention is a key symptom of ADHD, but the mechanisms underlying it are unclear. More specific approaches are needed to link disruptions in cognitive performance with ADHD behaviors. A pilot study found that even typically developing children did not maximally extract and combine information to maximize rewards in a cognitive task targeting attention selection mechanisms.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Anne B. Arnett, Gaelle Gourdet, Virginia Peisch, Katherine Spaulding, Erica Ferrara, Vivian Li
Summary: Children with ADHD show reduced average P3 amplitudes compared to TD children, possibly due to individual differences and increased trial variability. Greater ADHD symptom severity is associated with reduced mean P3 amplitude, but this correlation becomes insignificant after correcting for inter-trial differences in P3 latency. However, greater ADHD symptom severity is linked to reduced trial-to-trial variability in P3 amplitude.
CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Gisella Figlioli, Amandine Billaud, Thomas U. Ahearn, Natalia N. Antonenkova, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Marinus J. Blok, Natalia Bogdanova, Bernardo Bonanni, Barbara Burwinkel, Nicola J. Camp, Archie Campbell, Jose E. Castelao, Melissa H. Cessna, Stephen J. Chanock, Kamila Czene, Peter Devilee, Thilo Doerk, Christoph Engel, Mikael Eriksson, Peter A. Fasching, Jonine D. Figueroa, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat Garcia-Closas, Anna Gonzalez-Neira, Felix Grassmann, Pascal Guenel, Melanie Gundert, Andreas Hadjisavvas, Eric Hahnen, Per Hall, Ute Hamann, Patricia A. Harrington, Wei He, Peter Hillemanns, Antoinette Hollestelle, Maartje J. Hooning, Reiner Hoppe, Anthony Howell, Keith Humphreys, Agnes Jager, Anna Jakubowska, Elza K. Khusnutdinova, Yon-Dschun Ko, Vessela N. Kristensen, Annika Lindblom, Jolanta Lissowska, Jan Lubinski, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Dimitrios Mavroudis, William G. Newman, Nadia Obi, Mihalis Panayiotidis, Muhammad U. Rashid, Valerie Rhenius, Matti A. Rookus, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Mitul Shah, Reijo Sironen, Melissa C. Southey, Maija Suvanto, Rob A. E. M. Tollenaar, Ian Tomlinson, Therese Truong, Lizet E. van der Kolk, Elke M. van Veen, Barbara Wappenschmidt, Xiaohong R. Yang, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Michael Lush, Kyriaki Michailidou, Paul D. P. Pharoah, Qin Wang, Muriel A. Adank, Marjanka K. Schmidt, Irene L. Andrulis, Jenny Chang-Claude, Heli Nevanlinna, Georgia Chenevix-Trench, D. Gareth Evans, Roger L. Milne, Paolo Radice, Paolo Peterlongo
Summary: Evidence from the BRIDGES study suggests that germline protein truncating variants (PTVs) in FANCM are associated with increased risk of ER-negative and triple-negative breast cancer (TNBC), particularly for those with a family history. This study further investigates the association between FANCM missense variants (MVs) and breast cancer risk using the BRIDGES study, analyzing a total of 689 MVs. The results indicate that FANCM MVs may be low/moderate risk factors for ER-negative and TNBC subtypes of breast cancer.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2023)
Review
Biochemistry & Molecular Biology
Bocwinska-Kiluk Beata, Jelski Wojciech, Kornhuber Johannes, Lewczuk Piotr, Mroczko Barbara
Summary: There is a lack of empirical research on non-pharmacological interventions for Alzheimer's disease (AD) globally. This paper examines the biochemical, clinical, and social aspects of AD in relation to psychological interventions and their impact on patients' quality of life. Despite limited research, psychological interventions based on biochemical and other studies show potential for improving emotional well-being and slowing disease progression in AD patients. However, no effective methods of AD treatment have been established to date.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Christiane Muehle, Johannes Kornhuber
Summary: The activity of neutral sphingomyelinase (NSM) has been detected in human serum and plasma samples, which hydrolyzes fluorescently labeled sphingomyelin to ceramide. This discovery could lead to the development of new biomarkers or therapeutic targets for diseases affected by sphingolipid derangements.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Oncology
Hope S. Rugo, Seock-Ah Im, Fatima Cardoso, Javier Cortes, Giuseppe Curigliano, Antonino Musolino, Mark D. Pegram, Thomas Bachelot, Gail S. Wright, Cristina Saura, Santiago Escriva-de-Romani, Michelino De Laurentiis, Gary N. Schwartz, Timothy J. Pluard, Francesco Ricci, William R. Gwin II, Christelle Levy, Ursa Brown-Glaberman, Jean-Marc Ferrero, Maaike de Boer, Sung-Bae Kim, Katarina Petrakova, Denise A. Yardley, Orit Freedman, Erik H. Jakobsen, Einav Nili Gal-Yam, Rinat Yerushalmi, Peter A. Fasching, Peter A. Kaufman, Emily J. Ashley, Raul Perez-Olle, Shengyan Hong, Minori Koshiji Rosales, William J. Gradishar
Summary: Clinical trials often report initial results based on the primary end point, while additional results from secondary analyses may not be available. In this study comparing margetuximab and trastuzumab in breast cancer patients, the final overall survival analysis did not show an advantage of margetuximab over trastuzumab. However, exploratory analysis suggested potential improvements in specific patient groups based on CD16A genotyping.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Zhuxuan Fu, Maria Mori Brooks, Sarah Irvin, Susan Jordan, Katja K. H. Aben, Hoda Anton-Culver, Elisa Bandera, Matthias W. Beckmann, Andrew Berchuck, Angela Brooks-Wilson, Jenny Chang-Claude, Linda S. Cook, Daniel W. Cramer, Kara L. Cushing-Haugen, Jennifer A. Doherty, Arif B. Ekici, Peter A. Fasching, Renee T. Fortner, Simon A. Gayther, Aleksandra Gentry-Maharaj, Graham G. Giles, Ellen L. Goode, Marc T. Goodman, Holly R. Harris, Alexander Hein, Rudolf Kaaks, Lambertus A. Kiemeney, Martin Koebel, Joanne Kotsopoulos, Nhu D. Le, Alice W. Lee, Keitaro Matsuo, Valerie McGuire, John R. McLaughlin, Usha Menon, Roger L. Milne, Kirsten B. Moysich, Celeste Leigh Pearce, Malcolm C. Pike, Bo Qin, Susan J. Ramus, Marjorie J. Riggan, Joseph H. Rothstein, Joellen M. Schildkraut, Weiva Sieh, Rebecca Sutphen, Kathryn L. Terry, Pamela J. Thompson, Linda Titus, Anne M. van Altena, Emily White, Alice S. Whittemore, Anna H. Wu, Wei Zheng, Argyrios Ziogas, Sarah E. Taylor, Lu Tang, Thomas Songer, Nicolas Wentzensen, Penelope M. Webb, Harvey A. Risch, Francesmary Modugno
Summary: The lifetime ovulatory years (LOY) are positively associated with nonmucinous epithelial ovarian cancer (EOC) risk, implicating factors beyond ovulation in the development of EOC. The protective effects of parity and oral contraceptive use may not solely depend on anovulation.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Genetics & Heredity
Stefanie H. Mueller, Alvina G. Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Thais Baert, Laura E. Beane Freeman, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia Bogdanova, Stig E. Bojesen, Bernardo Bonanni, Hermann Brenner, Sara Y. Brucker, Saundra S. Buys, Jose E. Castelao, Tsun L. Chan, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Wendy K. Chung, Sarah Colonna, Sten Cornelissen, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dork, Laure Dossus, Miriam Dwek, Diana M. Eccles, Arif B. Ekici, A. Heather Eliassen, Christoph Engel, D. Gareth Evans, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Manuela Gago-Dominguez, Yu-Tang Gao, Montserrat Garcia-Closas, Jose A. Garcia-Saenz, Jeanine Genkinger, Aleksandra Gentry-Maharaj, Felix Grassmann, Pascal Guenel, Melanie Gundert, Lothar Haeberle, Eric Hahnen, Christopher A. Haiman, Niclas Hakansson, Per Hall, Elaine F. Harkness, Patricia A. Harrington, Jaana M. Hartikainen, Mikael Hartman, Alexander Hein, Weang-Kee Ho, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Richard S. Houlston, Anthony Howell, David J. Hunter, Dezheng Huo, Abctb Investigators, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M. John, Michael E. Jones, Audrey Jung, Rudolf Kaaks, Daehee Kang, Elza K. Khusnutdinova, Sung-Won Kim, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Katerina Kubelka-Sabit, Allison W. Kurian, Ava Kwong, James Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Keitaro Matsuo, Dimitrios Mavroudis, Usha Menon, Kenneth Muir, Rachel A. Murphy, Heli Nevanlinna, William G. Newman, Dieter Niederacher, Katie M. O'Brien, Nadia Obi, Kenneth Offit, Olufunmilayo Olopade, Andrew F. Olshan, Hakan Olsson, Sue K. Park, Alpa Patel, Achal Patel, Charles M. Perou, Julian Peto, Paul D. P. Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Paolo Radice, Dhanya Ramachandran, Muhammad U. Rashid, Gad Rennert, Atocha Romero, Kathryn J. Ruddy, Matthias Ruebner, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Marjanka K. Schmidt, Rita K. Schmutzler, Michael O. Schneider, Christopher Scott, Mitul Shah, Priyanka Sharma, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Harald Surowy, Rulla M. Tamimi, William J. Tapper, Jack A. Taylor, Soo Hwang Teo, Lauren R. Teras, Amanda E. Toland, Rob A. E. M. Tollenaar, Diana Torres, Gabriela Torres-Mejia, Melissa A. Troester, Therese Truong, Celine M. Vachon, Joseph Vijai, Clarice R. Weinberg, Camilla Wendt, Robert Winqvist, Alicja Wolk, Anna H. Wu, Taiki Yamaji, Xiaohong R. Yang, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M. Dunning, Douglas F. Easton, Harry Hemingway, Ute Hamann, Karoline B. Kuchenbaecker
Summary: This study identified 14 genes associated with breast cancer using gene-based aggregation analysis, including two newly discovered genes FMNL3 and AC058822.1. Furthermore, associations with established candidate genes like ESR1 were found through the collaboration of multi-ancestral cohorts, highlighting the importance of diversifying study cohorts. These findings provide new insights into the development of breast cancer.
Article
Medicine, General & Internal
Carla E. Schulmeyer, Peter A. Fasching, Lothar Haeberle, Julia Meyer, Michael Schneider, David Wachter, Matthias Ruebner, Patrik Poeschke, Matthias W. Beckmann, Arndt Hartmann, Ramona Erber, Paul Gass
Summary: The study evaluated the prognosis of patients with triple-negative breast cancer (TNBC) and other subtypes by using a biomarker panel including cytokeratin 5 (CK5), cluster of differentiation 117 (CD117), and epidermal growth factor receptor (EGFR). The results showed that the non-TBN subgroup of TNBC lesions with at least one positive biomarker (CK5, CD117, and/or EGFR) had longer disease-free survival (DFS) and overall survival (OS). This highlights the importance of molecular-based subclassifications of breast cancer for treatment options and prognosis stratification.
Article
Oncology
Raphela A. Ranjan, Julienne K. Muenzner, Philipp Kunze, Carol I. Geppert, Matthias Ruebner, Hanna Huebner, Peter A. Fasching, Matthias W. Beckmann, Tobias Baeuerle, Arndt Hartmann, Wolfgang Walther, Markus Eckstein, Ramona Erber, Regine Schneider-Stock
Summary: The biological and growth characteristics of two breast cancer cell lines were investigated in a CAM model, and the results confirmed the known features of the breast cancer cell lines observed in vitro and in cells. The CAM model was found to be a reliable alternative for breast cancer research, reducing the need for murine animal experiments.
Article
Cell Biology
Iulia Zoicas, Christiane Muehle, Fabian Schumacher, Burkhard Kleuser, Johannes Kornhuber
Summary: Currently, there are no animal models available for studying specific social fear and social fear with comorbidities. This study investigated whether social fear conditioning (SFC), an animal model for social anxiety disorder (SAD), leads to comorbidities and how it affects brain sphingolipid metabolism. The results showed that SFC altered emotional behavior and brain sphingolipid metabolism in a time-dependent manner. Social fear alone did not cause changes in non-social anxiety or depressive behavior, but comorbid depression developed five weeks after SFC, accompanied by alterations in sphingolipid metabolism in various brain regions.
Article
Pediatrics
Stefan A. Mestermann, Peter A. W. Fasching, Matthias W. Beckmann, Jennifer Gerlach, Oliver H. Kratz, Gunther H. Moll, Johannes Kornhuber, Anna Eichler
Summary: Pregnancy anamnesis is crucial for child and adolescent psychiatry diagnostics. This study aimed to evaluate women's recall of prenatal events and found that retrospective self-reporting was not always accurate. The reliability of self-reporting on prenatal alcohol, smoking, partnership quality, pregnancy satisfaction, and obstetric complications varied.
Article
Psychology, Multidisciplinary
Stefanie Horndasch, Elisabeth Sharon, Anna Eichler, Holmer Graap, Gunther H. Moll, Oliver Kratz
Summary: The study investigated aberrant emotional reactions toward body stimuli in anorexia nervosa patients and hypothesized altered heart rate reactions toward those highly significant and emotional stimuli. It found that anorexia nervosa patients showed greater overall change in heart rate relative to baseline when viewing pictures of women of different weight categories. Significant heart rate decelerations were observed for pictures of extremely underweight and overweight women, which were correlated with sociocultural attitudes toward appearance in the extremely underweight category.
BEHAVIORAL SCIENCES
(2023)
Article
Neurosciences
Eva-Maria Siegmann, Pauline Olm, Bernd Lenz, Christiane Muehle, Timo Jan Oberstein, Juan Manuel Maler, Johannes Kornhuber, Christopher M. William
Summary: This study examined the relationship between 2D:4D and the development and severity of AD. The results showed no significant association between 2D:4D and AD, but suggested a potential role of 2D:4D in depression in women.
Article
Chemistry, Medicinal
Nicolas Hoertel, Katayoun Rezaei, Marina Sanchez-Rico, Alfonso Delgado-Alvarez, Johannes Kornhuber, Erich Gulbins, Mark Olfson, Charles Ouazana-Vedrines, Alexander Carpinteiro, Celine Cougoule, Katrin Anne Becker, Jesus M. Alvarado, Frederic Limosin
Summary: The study suggests that the use of medications inhibiting acid sphingomyelinase (FIASMA) can reduce the risk of mortality in patients with SARS-CoV-2 infection. The multicenter retrospective observational study included 72,105 adult patients and found a significant association between FIASMA medication use and reduced 28-day mortality risk.
Article
Health Care Sciences & Services
Stefan Mestermann, Marie A. Arndt, Peter W. Fasching, Matthias Beckmann, Oliver H. Kratz, Gunther Moll, Johannes Kornhuber, Anna Eichler, IMAC Mind Consortium
Summary: This study analyzed paternal contributions to child well-being and found that father psychopathology significantly predicted girls' quality of life, while maternal parenting behavior had a significant influence on boys' quality of life. Fathers face different individual stressors and have different parenting behavior compared to mothers, but their influences are still significant, especially for daughters. Therefore, father-addressed pre- and intervention programs in child psychotherapeutic treatment are of high relevance.
