Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury

Reversible FMN dissociation from Escherichia coli respiratory complex I

(2016) Peter J. Holt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

(2016) Filippo Scialò et al.   Cell Metabolism

Global stroke statistics

(2016) Amanda G Thrift et al.   International Journal of Stroke

The architecture of respiratory supercomplexes

(2016) James A. Letts et al.   NATURE

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency

(2016) Adela Guarás et al.   Cell Reports

Scavenging of H2O2 by mouse brain mitochondria

(2014) Anatoly A. Starkov et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

The Oxygen Free Radicals Originating from Mitochondrial Complex I Contribute to Oxidative Brain Injury Following Hypoxia-Ischemia in Neonatal Mice

(2012) Z. V. Niatsetskaya et al.   JOURNAL OF NEUROSCIENCE

Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs

(2010) Rønnaug Solberg et al.   PLoS One

Reactions of the Flavin Mononucleotide in Complex I: A Combined Mechanism Describes NADH Oxidation Coupled to the Reduction of APAD+, Ferricyanide, or Molecular Oxygen

(2009) James A. Birrell et al.   BIOCHEMISTRY

Crystal structure of reduced thioredoxin reductase from Escherichia coli: Structural flexibility in the isoalloxazine ring of the flavin adenine dinucleotide cofactor

(2009) Brett W. Lennon et al.   PROTEIN SCIENCE

Generation of Reactive Oxygen Species by Mitochondrial Complex I: Implications in Neurodegeneration

(2008) Romana Fato et al.   NEUROCHEMICAL RESEARCH

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY