Hepatocyte-generated 27-hydroxycholesterol promotes the growth of melanoma by activation of estrogen receptor alpha

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

(2017) Amy E. Baek et al.   Nature Communications

Obesity, Inflammation, and Cancer

(2016) Tuo Deng et al.   Annual Review of Pathology-Mechanisms of Disease

From obesity to diabetes and cancer: epidemiological links and role of therapies

(2016) Custodia García-Jiménez et al.   BRITISH JOURNAL OF CANCER

Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline – Update 2016

(2016) Claus Garbe et al.   EUROPEAN JOURNAL OF CANCER

Estrogen receptor β in Merkel cell carcinoma: its possible roles in pathogenesis

(2016) Abdullah Azmahani et al.   HUMAN PATHOLOGY

Relationship Between Breast Density and Selective Estrogen-Receptor Modulators, Aromatase Inhibitors, Physical Activity, and Diet

(2016) Ernest U. Ekpo et al.   INTEGRATIVE CANCER THERAPIES

Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators

(2016) Georgette Moyle-Heyrman et al.   Journal of Ovarian Research

Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer

(2016) Bin Yuan et al.   Oncotarget

Obesity and Cancer: Local and Systemic Mechanisms

(2015) Neil M. Iyengar et al.   Annual Review of Medicine

Impact of the Obesity Epidemic on Cancer

(2015) Pamela J. Goodwin et al.   Annual Review of Medicine

Rethinking tamoxifen in the management of melanoma: New answers for an old question

(2015) Mariana P.C. Ribeiro et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Estrogen Receptor β Agonists Differentially Affect the Growth of Human Melanoma Cell Lines

(2015) Monica Marzagalli et al.   PLoS One

Gαi1and Gαi3regulate macrophage polarization by forming a complex containing CD14 and Gab1

(2015) Xianjing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPR-mediated direct mutation of cancer genes in the mouse liver

(2014) Wen Xue et al.   NATURE

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

(2014) J Zhu et al.   ONCOGENE

Obesity, diabetes, and survival outcomes in a large cohort of early-stage breast cancer patients

(2013) S. Jiralerspong et al.   ANNALS OF ONCOLOGY

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

(2013) E. R. Nelson et al.   SCIENCE

Cholesterol metabolism and cancer: the good, the bad and the ugly

(2012) Sandrine Silvente-Poirot et al.   CURRENT OPINION IN PHARMACOLOGY

Development of subtype-selective oestrogen receptor-based therapeutics

(2011) Stefan Nilsson et al.   NATURE REVIEWS DRUG DISCOVERY

Obesity promotes melanoma tumor growth: Role of leptin

(2010) Elizabeth L. Brandon et al.   CANCER BIOLOGY & THERAPY

Tamoxifen vs. non-tamoxifen treatment for advanced melanoma: a meta-analysis

(2010) Julieta Ruiz Beguerie et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Association between plasma total cholesterol concentration and incident prostate cancer in the CLUE II cohort

(2009) Alison M. Mondul et al.   CANCER CAUSES & CONTROL

27-Hydroxycholesterol Is an Endogenous Selective Estrogen Receptor Modulator

(2007) Carolyn D. DuSell et al.   MOLECULAR ENDOCRINOLOGY