Shikonin Inhibited Migration and Invasion of Human Lung Cancer Cells via Suppression of c-Met-Mediated Epithelial-to-Mesenchymal Transition

Prognostic Impact of Multiple Clinicopathologic Risk Factors and c-MET Overexpression in Patients Who Have Undergone Resection of Stage IB Non–Small-Cell Lung Cancer

(2016) In-Ho Kim et al.   Clinical Lung Cancer

MiR-206 inhibits HGF-induced epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via c-Met /PI3k/ Akt/mTOR pathway

(2016) Qing-yong Chen et al.   Oncotarget

Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib

(2015) Qiaoli Zhao et al.   INTERNATIONAL JOURNAL OF CANCER

Shikonin as an inhibitor of the LPS-induced epithelial-to-mesenchymal transition in human breast cancer cells

(2015) DARONG HONG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Traditional Chinese medicine and cancer: History, present situation, and development

(2015) Jie Liu et al.   Thoracic Cancer

High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients

(2015) Israel Cañadas et al.   Oncotarget

Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways

(2014) Yongqiang Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Induction of p21Waf1/Cip1 by Garcinol via Downregulation of p38-MAPK Signaling in p53-Independent H1299 Lung Cancer

(2014) Sheng-Yung Yu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer

(2013) I. Canadas et al.   CLINICAL CANCER RESEARCH

The Phytochemical Shikonin Stimulates Epithelial-Mesenchymal Transition (EMT) in Skin Wound Healing

(2013) Shu-Yi Yin et al.   Evidence-based Complementary and Alternative Medicine

Epithelial-mesenchymal transition leads to crizotinib resistance in H2228 lung cancer cells with EML4-ALK translocation

(2013) Hyeong Ryul Kim et al.   Molecular Oncology

MET Activation Mediates Resistance to Lapatinib Inhibition of HER2-Amplified Gastric Cancer Cells

(2012) C.-T. Chen et al.   MOLECULAR CANCER THERAPEUTICS

Overexpression of c-Met promotes invasion and metastasis of small oral tongue carcinoma

(2012) Young Chang Lim et al.   ORAL ONCOLOGY

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

(2012) Shang-Jyh Kao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways

(2011) Olorunseun O. Ogunwobi et al.   CLINICAL & EXPERIMENTAL METASTASIS

Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition

(2011) Li Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity

(2011) Ming-Hsien Chien et al.   FOOD AND CHEMICAL TOXICOLOGY

Hepatocyte Growth Factor Expression in EGFR Mutant Lung Cancer with Intrinsic and Acquired Resistance to Tyrosine Kinase Inhibitors in a Japanese Cohort

(2011) Seiji Yano et al.   Journal of Thoracic Oncology

Epithelial-Mesenchymal Transition Predicts Sensitivity to the Dual IGF-1R/IR Inhibitor OSI-906 in Hepatocellular Carcinoma Cell Lines

(2011) H. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

HGF Rescues Colorectal Cancer Cells from EGFR Inhibition via MET Activation

(2010) D. Liska et al.   CLINICAL CANCER RESEARCH

Shikonin inhibits tumor invasion via down-regulation of NF-κB-mediated MMP-9 expression in human ACC-M cells

(2010) R Min et al.   ORAL DISEASES

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The prognostic impact of NF-κB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer

(2008) S Al-Saad et al.   BRITISH JOURNAL OF CANCER

Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by shikonin was partly through the inactivation of NF-κB pathway

(2007) Min Ruan et al.   PHYTOTHERAPY RESEARCH