CD38 promotes angiotensin II-induced cardiac hypertrophy

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

(2016) Xiao-Hui Guan et al.   Oxidative Medicine and Cellular Longevity

Pathological Left Ventricular Hypertrophy and Stem Cells: Current Evidence and New Perspectives

(2016) Maria E. Marketou et al.   Stem Cells International

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic ADP-Ribose (cADPR) Mediate Ca2+ Signaling in Cardiac Hypertrophy Induced by β-Adrenergic Stimulation

(2016) Rukhsana Gul et al.   PLoS One

The role of sirtuins in cardiac disease

(2015) Shouji Matsushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

An Adenosine A1 Agonist 2-Chloro-N6 Cyclopentyladenosine Inhibits the Angiotensin II-Induced Cardiomyocyte Hypertrophy through the Calcineurin Pathway

(2014) Xingliang Zhang et al.   CARDIOLOGY

Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Dao-Fu Dai et al.   ANTIOXIDANTS & REDOX SIGNALING

Sirtuin 6 protects cardiomyocytes from hypertrophyin vitrovia inhibition of NF-κB-dependent transcriptional activity

(2012) Shan-Shan Yu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Ca2+ influx through L-type Ca2+ channels and transient receptor potential channels activates pathological hypertrophy signaling

(2012) Hui Gao et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

(2012) Nagalingam R Sundaresan et al.   NATURE MEDICINE

The NAD ratio redox paradox: why does too much reductive power cause oxidative stress?

(2012) João Soeiro Teodoro et al.   TOXICOLOGY MECHANISMS AND METHODS

Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy

(2011) Gipsy Majumdar et al.   PHYSIOLOGICAL GENOMICS

Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca2+ overload

(2010) Yan Ge et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial SIRT3 and heart disease

(2010) V. B. Pillai et al.   CARDIOVASCULAR RESEARCH

Sirt1 acts in association with PPAR  to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

(2010) A. Planavila et al.   CARDIOVASCULAR RESEARCH

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

The IP 3 Receptor Regulates Cardiac Hypertrophy in Response to Select Stimuli

(2010) Hiroyuki Nakayama et al.   CIRCULATION RESEARCH

Transgenic Overexpression of Aldehyde Dehydrogenase-2 Rescues Chronic Alcohol Intake–Induced Myocardial Hypertrophy and Contractile Dysfunction

(2009) Thomas A. Doser et al.   CIRCULATION

CD38 as a Regulator of Cellular NAD: A Novel Potential Pharmacological Target for Metabolic Conditions

(2009) Eduardo Chini   CURRENT PHARMACEUTICAL DESIGN

CD38/cADPR/Ca2+Pathway Promotes Cell Proliferation and Delays Nerve Growth Factor-induced Differentiation in PC12 Cells

(2009) Jianbo Yue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

(2008) Michael R. MacDonald et al.   EUROPEAN HEART JOURNAL

Epigenetic regulation of cardiac muscle-specific genes in H9c2 cells by Interleukin-18 and histone deacetylase inhibitor m-carboxycinnamic acid bis-hydroxamide

(2008) Gipsy Majumdar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY