Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca2+leak in HEK293 cells

Selective transport of neurotransmitters and –modulators by distinct volume-regulated LRRC8 anion channels

(2017) Darius Lutter et al.   JOURNAL OF CELL SCIENCE

Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes

(2016) Héctor Gaitán-Peñas et al.   BIOPHYSICAL JOURNAL

TMCO1 Is an ER Ca 2+ Load-Activated Ca 2+ Channel

(2016) Qiao-Chu Wang et al.   CELL

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

(2016) Ruhma Syeda et al.   CELL

LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis

(2016) Hyehun Choi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop

(2016) Florian Ullrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs

(2015) R. Planells-Cases et al.   EMBO JOURNAL

VRAC: molecular identification as LRRC8 heteromers with differential functions

(2015) Thomas J. Jentsch et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel

(2014) Zhaozhu Qiu et al.   CELL

The Protein Synthesis Inhibitor Blasticidin S Enters Mammalian Cells via Leucine-rich Repeat-containing Protein 8D

(2014) Clarissa C. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function

(2014) Lalit Kumar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

LRRC8A protein is indispensable for swelling-activated and ATP-induced release of excitatory amino acids in rat astrocytes

(2014) María C. Hyzinski-García et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC

(2014) F. K. Voss et al.   SCIENCE

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

(2014) Junji Suzuki et al.   Nature Communications

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

Contribution of Intracellular Calcium and pH in Ischemic Uncoupling of Cardiac Gap Junction Channels Formed of Connexins 43, 40, and 45: A Critical Function of C-Terminal Domain

(2013) Giriraj Sahu et al.   PLoS One

LRRC8 proteins share a common ancestor with pannexins, and may form hexameric channels involved in cell-cell communication

(2012) Federico Abascal et al.   BIOESSAYS

Pannexin 3 functions as an ER Ca2+channel, hemichannel, and gap junction to promote osteoblast differentiation

(2011) Masaki Ishikawa et al.   JOURNAL OF CELL BIOLOGY

Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties

(2011) Z Huang et al.   ONCOGENE

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk

(2011) E. Zampese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

(2010) Eva Sammels et al.   CELL CALCIUM

Translocon closure to Ca2+ leak in proliferating vascular smooth muscle cells

(2009) Mohamed S Amer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake

(2009) Lucia Brunello et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols