Causes and consequences of nuclear gene positioning

The 3D Genome as Moderator of Chromosomal Communication

(2016) Job Dekker et al.   CELL

Nucleoporin genes in human diseases

(2016) Valeria Nofrini et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Nucleoporin-mediated regulation of cell identity genes

(2016) Arkaitz Ibarra et al.   GENES & DEVELOPMENT

Strategies to regulate transcription factor–mediated gene positioning and interchromosomal clustering at the nuclear periphery

(2016) Carlo Randise-Hinchliff et al.   JOURNAL OF CELL BIOLOGY

Locus-specific gene repositioning in prostate cancer

(2016) Marc Leshner et al.   MOLECULAR BIOLOGY OF THE CELL

Compaction and segregation of sister chromatids via active loop extrusion

(2016) Anton Goloborodko et al.   eLife

Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool

(2016) Karen J. Meaburn   Frontiers in Genetics

Identification of Gene Positioning Factors Using High-Throughput Imaging Mapping

(2015) Sigal Shachar et al.   CELL

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos

(2015) Adriana Gonzalez-Sandoval et al.   CELL

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

(2015) Darío G. Lupiáñez et al.   CELL

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

(2015) Ya Guo et al.   CELL

CTCF Binding Polarity Determines Chromatin Looping

(2015) Elzo de Wit et al.   MOLECULAR CELL

Three-dimensional genome architecture: players and mechanisms

(2015) Ana Pombo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

(2015) Adrian L. Sanborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells

(2014) Pierre Therizols et al.   SCIENCE

Light-regulated gene repositioning in Arabidopsis

(2014) Chun-Miao Feng et al.   Nature Communications

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

(2013) Jop Kind et al.   CELL

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Functional implications of genome topology

(2013) Giacomo Cavalli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

(2013) M. Y. Tolstorukov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of the Mitotic Chromosome

(2013) N. Naumova et al.   SCIENCE

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

(2012) Inês Pinheiro et al.   CELL

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

(2012) Joseph M. Zullo et al.   CELL

Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery

(2012) Benjamin D. Towbin et al.   CELL

Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression

(2012) E. Josephine Clowney et al.   CELL

Transcription Factor Binding to a DNA Zip Code Controls Interchromosomal Clustering at the Nuclear Periphery

(2012) Donna Garvey Brickner et al.   DEVELOPMENTAL CELL

Perinuclear positioning of the inactive human cystic fibrosis gene depends on CTCF, A-type lamins and an active histone deacetylase

(2012) Joscha S. Muck et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Iterative correction of Hi-C data reveals hallmarks of chromosome organization

(2012) Maxim Imakaev et al.   NATURE METHODS

Identification of Genes That Promote or Antagonize Somatic Homolog Pairing Using a High-Throughput FISH–Based Screen

(2012) Eric F. Joyce et al.   PLoS Genetics

An Epigenetic Signature for Monoallelic Olfactory Receptor Expression

(2011) Angeliki Magklara et al.   CELL

An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity

(2011) Anna Mattout et al.   CURRENT BIOLOGY

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements

(2011) O. Hakim et al.   GENOME RESEARCH

The spatial dynamics of tissue-specific promoters during C. elegans development

(2010) P. Meister et al.   GENES & DEVELOPMENT

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery

(2010) Sara Ahmed et al.   NATURE CELL BIOLOGY

Topographic Mapping--The Olfactory System

(2010) T. Imai et al.   Cold Spring Harbor Perspectives in Biology

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

The role of nuclear pores in gene regulation, development and disease

(2009) Maya Capelson et al.   EMBO REPORTS

Disease-specific gene repositioning in breast cancer

(2009) Karen J. Meaburn et al.   JOURNAL OF CELL BIOLOGY

The SWI/SNF complex and cancer

(2009) D Reisman et al.   ONCOGENE

The B-type lamin is required for somatic repression of testis-specific gene clusters

(2009) Y. Y. Shevelyov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

The Meaning of Gene Positioning

(2008) Takumi Takizawa et al.   CELL

Locus-specific and activity-independent gene repositioning during early tumorigenesis

(2008) Karen J. Meaburn et al.   JOURNAL OF CELL BIOLOGY

A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

(2008) R. Ileng Kumaran et al.   JOURNAL OF CELL BIOLOGY

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

(2008) K. L. Reddy et al.   NATURE

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

(2008) Lee E. Finlan et al.   PLoS Genetics