Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes

Protons Trigger Mitochondrial Flashes

(2016) Xianhua Wang et al.   BIOPHYSICAL JOURNAL

Systems proteomics of liver mitochondria function

(2016) E. G. Williams et al.   SCIENCE

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation

(2016) Rafael Pérez-Pérez et al.   Cell Reports

Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics

(2016) Wenwen Li et al.   Scientific Reports

Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart

(2015) Guohua Gong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Respiratory supercomplexes plasticity and implications

(2015) Yidong Bai   Frontiers in Bioscience-Landmark

Stomatin-Like Protein 2 Is Required forIn VivoMitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function

(2015) Panagiotis Mitsopoulos et al.   MOLECULAR AND CELLULAR BIOLOGY

C11orf83, a Mitochondrial Cardiolipin-Binding Protein Involved inbc1Complex Assembly and Supercomplex Stabilization

(2015) Marjorie Desmurs et al.   MOLECULAR AND CELLULAR BIOLOGY

DNAJC19, a Mitochondrial Cochaperone Associated with Cardiomyopathy, Forms a Complex with Prohibitins to Regulate Cardiolipin Remodeling

(2014) Ricarda Richter-Dennerlein et al.   Cell Metabolism

Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond

(2014) Tingting Hou et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans

(2014) En-Zhi Shen et al.   NATURE

Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo

(2014) Michael O Breckwoldt et al.   NATURE MEDICINE

Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations

(2014) ChongShu Jian et al.   Science China-Life Sciences

OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange

(2013) Jaime Santo-Domingo et al.   EMBO JOURNAL

Respective Contribution of Mitochondrial Superoxide and pH to Mitochondria-targeted Circularly Permuted Yellow Fluorescent Protein (mt-cpYFP) Flash Activity

(2013) Lan Wei-LaPierre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Triggering of Superoxide Flashes by Mitochondrial Ca2+Uniport and Basal Reactive Oxygen Species Elevation

(2013) Tingting Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Superoxide constitutes a major signal of mitochondrial superoxide flash

(2013) Xing Zhang et al.   LIFE SCIENCES

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle

(2013) Kazuhiro Ikeda et al.   Nature Communications

Superoxide Flashes Reveal Novel Properties of Mitochondrial Reactive Oxygen Species Excitability in Cardiomyocytes

(2012) Kaitao Li et al.   BIOPHYSICAL JOURNAL

Identification of a Protein Mediating Respiratory Supercomplex Stability

(2012) Yu-Chan Chen et al.   Cell Metabolism

Rcf1 Mediates Cytochrome Oxidase Assembly and Respirasome Formation, Revealing Heterogeneity of the Enzyme Complex

(2012) Milena Vukotic et al.   Cell Metabolism

Superoxide flashes: Elemental events of mitochondrial ROS signaling in the heart

(2012) Xianhua Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Rcf1 and Rcf2, Members of the Hypoxia-Induced Gene 1 Protein Family, Are Critical Components of the Mitochondrial Cytochrome bc1-Cytochrome c Oxidase Supercomplex

(2012) V. Strogolova et al.   MOLECULAR AND CELLULAR BIOLOGY

Prohibitin 1 Modulates Mitochondrial Stress-Related Autophagy in Human Colonic Epithelial Cells

(2012) Arwa S. Kathiria et al.   PLoS One

Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

(2011) Thorsten Althoff et al.   EMBO JOURNAL

Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease

(2011) Lan Wei et al.   FASEB JOURNAL

Superoxide Flashes

(2011) Qi Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography

(2011) N. V. Dudkina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

(2010) Graham M. Strub et al.   FASEB JOURNAL

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

(2009) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Prohibitins and the functional compartmentalization of mitochondrial membranes

(2009) C. Osman et al.   JOURNAL OF CELL SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids

(2008) Katsumi Kasashima et al.   EXPERIMENTAL CELL RESEARCH

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

(2008) C. Merkwirth et al.   GENES & DEVELOPMENT

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

(2008) Michael Schleicher et al.   JOURNAL OF CELL BIOLOGY

Respiratory Active Mitochondrial Supercomplexes

(2008) Rebeca Acín-Pérez et al.   MOLECULAR CELL