Glucose deprivation induces primary cilium formation through mTORC1 inactivation

The Cilium: Cellular Antenna and Central Processing Unit

(2017) Jarema J. Malicki et al.   TRENDS IN CELL BIOLOGY

Autophagy and primary cilia: dual interplay

(2016) Olatz Pampliega et al.   CURRENT OPINION IN CELL BIOLOGY

Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia

(2016) Mingming Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

(2016) Idil Orhon et al.   NATURE CELL BIOLOGY

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

(2016) Karsten Boldt et al.   Nature Communications

Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways

(2015) Shixuan Wang et al.   Autophagy

Rabin8 suppresses autophagosome formation independently of its guanine nucleotide-exchange activity towards Rab8

(2015) Yuta Amagai et al.   JOURNAL OF BIOCHEMISTRY

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1

(2015) Guoxiang Jin et al.   MOLECULAR CELL

Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

(2015) Jongshin Kim et al.   Nature Communications

Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade

(2015) Richa Tyagi et al.   Cell Reports

Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis

(2014) Toshiaki Oda et al.   GENES TO CELLS

The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation

(2014) Christel Thauvin-Robinet et al.   NATURE GENETICS

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

(2013) Bine H Villumsen et al.   EMBO JOURNAL

NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15

(2013) Shuhei Chiba et al.   EMBO JOURNAL

Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation

(2013) Natasha T. Snider et al.   JOURNAL OF CELL BIOLOGY

Nutrient Sensing, Metabolism, and Cell Growth Control

(2013) Hai-Xin Yuan et al.   MOLECULAR CELL

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation

(2012) S. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Ciliogenesis: building the cell's antenna

(2011) Hiroaki Ishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR signaling in polycystic kidney disease

(2011) Oxana Ibraghimov-Beskrovnaya et al.   TRENDS IN MOLECULAR MEDICINE

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

(2010) Laura R. Pearce et al.   BIOCHEMICAL JOURNAL

Oct1 is required for mTOR-induced G1cell cycle arrest via the control of p27Kip1expression

(2010) Mathieu Dalvai et al.   CELL CYCLE

Ofd1, a Human Disease Gene, Regulates the Length and Distal Structure of Centrioles

(2010) Veena Singla et al.   DEVELOPMENTAL CELL

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Functional genomic screen for modulators of ciliogenesis and cilium length

(2010) Joon Kim et al.   NATURE

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

(2009) Jantje M. Gerdes et al.   CELL

Control of Centriole Length by CPAP and CP110

(2009) Thorsten I. Schmidt et al.   CURRENT BIOLOGY

Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy

(2009) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway

(2008) Linda M. DiBella et al.   HUMAN MOLECULAR GENETICS

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

(2008) Tiffiney R. Hartman et al.   HUMAN MOLECULAR GENETICS