Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity

The importance of nerve microenvironment for schwannoma development

(2016) Alexander Schulz et al.   ACTA NEUROPATHOLOGICA

Strength of ERK1/2 MAPK Activation Determines Its Effect on Myelin and Axonal Integrity in the Adult CNS

(2016) Akihiro Ishii et al.   JOURNAL OF NEUROSCIENCE

Inhibition of YAP/TAZ Activity in Spinal Cord Suppresses Neuropathic Pain

(2016) N. Xu et al.   JOURNAL OF NEUROSCIENCE

Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS

(2016) E. Domenech-Estevez et al.   JOURNAL OF NEUROSCIENCE

The repair Schwann cell and its function in regenerating nerves

(2016) K. R. Jessen et al.   JOURNAL OF PHYSIOLOGY-LONDON

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

(2016) Yannick Poitelon et al.   NATURE NEUROSCIENCE

An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression

(2015) H. Hayashi et al.   CANCER RESEARCH

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

The Role of Cell Plasticity in Tissue Repair: Adaptive Cellular Reprogramming

(2015) Kristjan R. Jessen et al.   DEVELOPMENTAL CELL

Visualizing Peripheral Nerve Regeneration by Whole Mount Staining

(2015) Xin-peng Dun et al.   PLoS One

The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity

(2014) Tadanori Shimomura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Schwannomas and Their Pathogenesis

(2014) David A. Hilton et al.   BRAIN PATHOLOGY

Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus

(2014) Wei Li et al.   CANCER CELL

Molecular insights into NF2 /Merlin tumor suppressor function

(2014) Jonathan Cooper et al.   FEBS LETTERS

A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

(2014) Jeffrey R. Gehlhausen et al.   HUMAN MOLECULAR GENETICS

Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration

(2014) Michio W. Painter et al.   NEURON

A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response

(2014) Dan Shao et al.   Nature Communications

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves

(2014) Alexander Schulz et al.   Jove-Journal of Visualized Experiments

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells

(2013) Robin D. S. Doddrell et al.   BRAIN

Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling

(2013) Alexander Schulz et al.   BRAIN

Motor Axon Regeneration and Muscle Reinnervation in Young Adult and Aged Animals

(2013) H. Kang et al.   JOURNAL OF NEUROSCIENCE

Merlin isoform 2 in neurofibromatosis type 2–associated polyneuropathy

(2013) Alexander Schulz et al.   NATURE NEUROSCIENCE

Tumor-Associated Macrophages Are Related to Volumetric Growth of Vestibular Schwannomas

(2013) Maurits de Vries et al.   OTOLOGY & NEUROTOLOGY

Plastic Fantastic: Schwann Cells and Repair of the Peripheral Nervous System

(2013) Haesun A. Kim et al.   Stem Cells Translational Medicine

Genetic disruption ofPtenin a novel mouse model of tomaculous neuropathy

(2012) Sandra Goebbels et al.   EMBO Molecular Medicine

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

(2012) Xavier Fontana et al.   JOURNAL OF CELL BIOLOGY

p38 MAPK Activation Promotes Denervated Schwann Cell Phenotype and Functions as a Negative Regulator of Schwann Cell Differentiation and Myelination

(2012) D. P. Yang et al.   JOURNAL OF NEUROSCIENCE

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

(2010) S. Goebbels et al.   JOURNAL OF NEUROSCIENCE

A Novel Motion Analysis Approach Reveals Late Recovery in C57BL/6 Mice and Deficits in NCAM-Deficient Mice after Sciatic Nerve Crush

(2010) Andreas Fey et al.   JOURNAL OF NEUROTRAUMA

Neurofibromatosis type 2

(2009) Ashok R Asthagiri et al.   LANCET

Dissecting and Targeting the Growth Factor-Dependent and Growth Factor-Independent Extracellular Signal-Regulated Kinase Pathway in Human Schwannoma

(2008) S. Ammoun et al.   CANCER RESEARCH

E-cadherin expression in postnatal Schwann cells is regulated by the cAMP-dependent protein kinase a pathway

(2008) Audrita T. Crawford et al.   GLIA

Increase of MCP-1 (CCL2) in myelin mutant Schwann cells is mediated by MEK-ERK signaling pathway

(2008) Stefan Fischer et al.   GLIA

c-Jun is a negative regulator of myelination

(2008) David B. Parkinson et al.   JOURNAL OF CELL BIOLOGY

Tumor Suppressor Schwannomin/Merlin Is Critical for the Organization of Schwann Cell Contacts in Peripheral Nerves

(2008) N. Denisenko et al.   JOURNAL OF NEUROSCIENCE

Schwann cell proliferation during Wallerian degeneration is not necessary for regeneration and remyelination of the peripheral nerves: Axon-dependent removal of newly generated Schwann cells by apoptosis

(2008) David P. Yang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Magic but treatable? Tumours due to loss of Merlin

(2007) C. O. Hanemann   BRAIN

Monocyte chemoattractant protein-1 is a pathogenic component in a model for a hereditary peripheral neuropathy

(2007) Stefan Fischer et al.   MOLECULAR AND CELLULAR NEUROSCIENCE