Review
Obstetrics & Gynecology
Aine Brislane, Nicholas F. Sculthorpe, Margie H. Davenport, Alexander Beaumont
Summary: Aerobic exercise training improves flow-mediated dilation for postmenopausal individuals, especially in controlled interventions.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2022)
Review
Physiology
Qiuping You, Laikang Yu, Gen Li, Hui He, Yuanyuan Lv
Summary: The study indicated that aerobic exercise is beneficial for improving vascular endothelial function in healthy middle-aged and elderly people, especially vigorous-intensity aerobic exercise, with a duration of 8 weeks or above showing more significant effects.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Sport Sciences
Laura Fuertes-Kenneally, Agustin Manresa-Rocamora, Carles Blasco-Peris, Fernando Ribeiro, Noemi Sempere-Ruiz, Jose Manuel Sarabia, Vicente Climent-Paya
Summary: Exercise-based cardiac rehabilitation is effective in enhancing endothelial function in patients with heart failure, but the optimal exercise dose is still unknown.
SPORTS MEDICINE-OPEN
(2023)
Review
Physiology
Laura Fuertes-Kenneally, Carles Blasco-Peris, Antonio Casanova-Lizon, Sabina Baladzhaeva, Vicente Climent, Jose Manuel Sarabia, Agustin Manresa-Rocamora
Summary: This study aimed to evaluate the effect of high-intensity interval training (HIIT) compared to moderate intensity training (MIT) and other exercise modalities on endothelial function in patients with cardiovascular disease. The results showed that long HIIT was superior to MIT in improving brachial flow-mediated dilation (FMD) in patients with coronary artery disease and heart failure.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Sport Sciences
Jenna L. Taylor, Shelley E. Keating, David J. Holland, Daniel J. Green, Jeff S. Coombes, Tom G. Bailey
Summary: The study found that a 4-week high-intensity interval training program was more effective in improving vascular function compared to moderate intensity continuous training but there were no significant differences in vascular function, blood pressure, and arterial stiffness between the two training methods over 12 months.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2022)
Review
Rheumatology
Tiago Pecanha, Daniel J. Bannell, Sofia Mendes Sieczkowska, Nicola Goodson, Hamilton Roschel, Victoria S. Sprung, David A. Low
Summary: Physical activity has a beneficial impact on microvascular and macrovascular function in patients with autoimmune rheumatic diseases, but does not show clear effects on macrovascular structure.
Review
Sport Sciences
Chen Zheng, Xiaoyuan Zhang, Sinead Sheridan, Robin Sze-Tak Ho, Cindy Hui-Ping Sit, Yu Huang, Stephen Heung-Sang Wong
Summary: This systematic review and meta-analysis found that short-term SB interventions improved FMD and increased SR, but had no significant effect on PWV. Long-term SB interventions resulted in a slight increase in FMD and had no significant effect on PWV. This suggests that short-term interventions had a greater impact on improving lower extremity arterial function.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Review
Sport Sciences
Francisco Javier Soto-Rodriguez, Eva Isidoro Cabanas, Jose Manuel Perez-Marmol
Summary: Prolonged sitting can affect endothelial function, and strategies that interrupt sitting have shown significant improvements in shear rate, flow-mediated dilation, and blood flow, thus playing a crucial role in preventing endothelial dysfunction.
JOURNAL OF SPORTS SCIENCES
(2022)
Review
Sport Sciences
Yujia Liu, Ning Jiang, Fangfang Pang, Tong Chen
Summary: This meta-analysis examined the effects of resistance training on vascular function, finding that resistance training with blood flow restriction has a more positive effect on regulating arterial compliance, but not on vascular function.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE
(2021)
Review
Chemistry, Medicinal
Yahya Jalilpiran, Maryam Hajishafiee, Masoud Khorshidi, Hamid Rezvani, Mohsen Mohammadi-Sartang, Jamal Rahmani, Seyed Mohammad Mousavi
Summary: The systematic review and meta-analysis found that ALA supplementation significantly increased FMD levels, with effects potentially influenced by participant age and health status. Dose-response analysis also indicated a significant non-linear effect of ALA dosage on FMD levels. Further research is needed to explore the effects of ALA supplementation on other biomarkers of EF.
PHYTOTHERAPY RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Andreas B. Gevaert, Birgit Boehm, Haley Hartmann, Inge Goovaerts, Tibor Stoop, Caroline M. Van De Heyning, Paul J. Beckers, Flavia Baldassarri, Stephan Mueller, Renate Oberhoffer, Andre Duvinage, Mark J. Haykowsky, Ulrik Wisloff, Volker Adams, Burkert Pieske, Martin Halle, Emeline M. Van Craenenbroeck
Summary: This study investigated the effects of MICT and HIIT on vascular function and repair in HFpEF. The results showed that these training methods did not change vascular function or cellular endothelial repair. This did not significantly contribute to the improvement of VO2peak in HFpEF patients.
JACC-HEART FAILURE
(2023)
Review
Biochemistry & Molecular Biology
Ai Yin Lim, Yi-Ching Chen, Chih-Chin Hsu, Tieh-Cheng Fu, Jong-Shyan Wang
Summary: This systematic review investigated the effect of exercise training on mitochondrial function in cardiovascular disease (CVD) patients. The results showed that exercise can improve mitochondrial morphology, biogenesis, and significantly enhance oxidative capacity in CVD patients. However, the effects on mitochondrial dynamics, antioxidant capacity, and quality were inconclusive or inadequate. Further research, including randomized controlled trials, is needed to explore the pathways through which exercise modifies mitochondrial quantity and quality in CVD patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Jin-Su Kim, Do Gyun Lee, Moon-Hyon Hwang
Summary: This study aimed to compare the vascular responses to moderate-intensity treadmill running in high PM2.5 (HPM2.5) and low PM2.5 (LPM2.5) conditions in healthy young males. The results showed that acute PM2.5 exposure can counteract the positive effect of aerobic exercise on vascular endothelial function in young males.
APPLIED SCIENCES-BASEL
(2023)
Article
Cardiac & Cardiovascular Systems
Hugo Gravel, Parya Behzadi, Sarah Cardinal, Hadiatou Barry, Paul-Eduard Neagoe, Martin Juneau, Anil Nigam, Martin G. Sirois, Daniel Gagnon
Summary: The study found that in patients with stable coronary artery disease, a typical Finnish sauna bathing session acutely improves peripheral flow-mediated dilation, but has no effect on postocclusive reactive hyperemia.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Review
Clinical Neurology
Dimitrios Delialis, Georgios Mavraganis, Anna Dimoula, Raphael Patras, Angeliki-Maria Dimopoulou, Alexandros Sianis, Erold Ajdini, Eleni Maneta, Nikolaos Kokras, Kimon Stamatelopoulos, Georgios Georgiopoulos
Summary: The study found that selective serotonin receptor inhibitors (SSRIs) have a positive effect on improving endothelial function, which is an early marker of atherosclerotic cardiovascular disease (ASCVD). Through a systematic evaluation of longitudinal changes in patients with depression who received SSRIs treatment, it was found that SSRIs significantly increase flow-mediated dilation (FMD), the gold-standard marker of endothelial function. This has important implications for understanding treatment strategies for depression and established or subclinical ASCVD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Chemistry, Analytical
Kate S. Early, Nathan P. Lemoine, Annie Simoneaux, Shelly Mullenix, Jack Marucci, Michael J. MacLellan, Neil M. Johannsen
Summary: This study aimed to describe the physical demands of American football players using novel performance analysis techniques. Results showed differences in physical demands and activity levels between players in different positions and on offense and defense sides.
Article
Nutrition & Dietetics
Rachel Matthews, Kate S. Early, Cullen M. Vincellette, Jack Losso, Guillaume Spielmann, Brian A. Irving, Timothy D. Allerton
Summary: Heart rate variability (HRV) is a useful tool for assessing autonomic function and cardiometabolic disease. Reduced HRV and nitric oxide (NO) bioavailability are associated with autonomic dysfunction. This study found that daily watermelon juice (WMJ) supplementation improved HRV in response to an oral glucose challenge (OGC). It also emphasized the importance of NO bioavailability in autonomic dysfunction in cardiometabolic disease.