期刊
JOURNAL OF BIOTECHNOLOGY
卷 255, 期 -, 页码 33-36出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jbiotec.2017.06.1197
关键词
Organohalide respiration; Anaerobic respiration; Tetrachloroethene; Vitamin B12; Nitrous oxide reduction; Thiosulfate oxidation
资金
- German Research Council (DFG) [FOR1530]
Sulfurospirillum halorespirans is a bacterium that couples the reductive dehalogenation of chlorinated ethenes to growth. This process is called organohalide respiration (OHR), which can be of importance for bioremediation. Here, we report the complete genome of S. halorespirans, the second one of an organohalide-respiring Epsilonproteobacterium after that of Sulfurospirillum multivorans. With both genomes at hand, we were able to ascertain that the genomic region encoding OHR proteins in Epsilonproteobacteria differs from that found in organohalide-respiring bacteria (OHRB) affiliated to other phyla and that the production of a unique cobamide, norpseudo-B-12, might not be limited to the model organism S. multivorans. The OHR region is virtually identical in both organisms with differences only in the gene sequence of the key enzyme of OHR, the PCE reductive dehalogenase (PceA), and in regulatory regions. This is of interest, since the availability of natural, closely related variants opens an avenue to study the poorly understood OHRB, which withstand systematic genetic manipulation so far.
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