Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

(2017) Charles N. Serhan   FASEB JOURNAL

A mutation in ADIPOR1 causes nonsyndromic autosomal dominant retinitis pigmentosa

(2016) Jinlu Zhang et al.   HUMAN GENETICS

ADIPOR1Is Mutated in Syndromic Retinitis Pigmentosa

(2016) Mingchu Xu et al.   HUMAN MUTATION

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

NPD1-mediated stereoselective regulation of BIRC3 expression through cREL is decisive for neural cell survival

(2015) J M Calandria et al.   CELL DEATH AND DIFFERENTIATION

Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival

(2015) Dennis S. Rice et al.   Nature Communications

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Docosahexaenoic acid confers enduring neuroprotection in experimental stroke

(2014) Sung-Ha Hong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq

(2013) C. D. Arnold et al.   SCIENCE

Signal transduction by tumor necrosis factor receptors

(2012) Lucía Cabal-Hierro et al.   CELLULAR SIGNALLING

A molecular view on signal transduction by the apoptosome

(2012) Thomas F. Reubold et al.   CELLULAR SIGNALLING

Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1

(2012) Jorgelina M. Calandria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docosahexaenoic Acid Signaling Modulates Cell Survival in Experimental Ischemic Stroke Penumbra and Initiates Long-Term Repair in Young and Aged Rats

(2012) Tiffany N. Eady et al.   PLoS One

A novel role for RIP1 kinase in mediating TNFα production

(2012) D E Christofferson et al.   Cell Death & Disease

Mechanisms of Gene Regulation by Fatty Acids

(2012) Anastasia Georgiadi et al.   Advances in Nutrition

Synaptic and Extrasynaptic NMDA Receptors Differentially Modulate Neuronal Cyclooxygenase-2 Function, Lipid Peroxidation, and Neuroprotection

(2011) D. T. Stark et al.   JOURNAL OF NEUROSCIENCE

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

(2011) William J. Kaiser et al.   NATURE

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis

(2010) Zahra Faghiri et al.   EXPERIMENTAL EYE RESEARCH

cIAP1 Cooperatively Inhibits Procaspase-3 Activation by the Caspase-9 Apoptosome

(2010) Stephen P. Burke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotectin D1 Induces Dephosphorylation of Bcl-xLin a PP2A-dependent Manner during Oxidative Stress and Promotes Retinal Pigment Epithelial Cell Survival

(2010) Rajee Antony et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1

(2010) Nicolas G. Bazan et al.   JOURNAL OF LIPID RESEARCH

Asymmetric Recruitment of cIAPs by TRAF2

(2010) Peter D. Mace et al.   JOURNAL OF MOLECULAR BIOLOGY

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

(2010) Liwei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

(2010) Giuseppe Astarita et al.   PLoS One

Docosahexaenoic Acid Therapy of Experimental Ischemic Stroke

(2010) Ludmila Belayev et al.   Translational Stroke Research

Overexpression of the nuclear factor-κB subunit c-Rel protects against human islet cell death in vitro

(2009) Dariush Mokhtari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

cIAP1, cIAP2, and XIAP Act Cooperatively via Nonredundant Pathways to Regulate Genotoxic Stress-Induced Nuclear Factor- B Activation

(2009) H.-S. Jin et al.   CANCER RESEARCH

TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis

(2009) James E. Vince et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Survival Rescue in 15-Lipoxygenase-1-deficient Retinal Pigment Epithelial Cells by the Novel Docosahexaenoic Acid-derived Mediator, Neuroprotectin D1

(2009) Jorgelina M. Calandria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

(2008) Eugene Varfolomeev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia

(2008) Ilenia Sarnico et al.   JOURNAL OF NEUROCHEMISTRY

c-Rel, an NF- B family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation

(2008) H. J. Ahn et al.   LEARNING & MEMORY

Apoptosis and necrosis: Detection, discrimination and phagocytosis

(2008) Dmitri V. Krysko et al.   METHODS

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL