Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms

A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury

(2016) Edward T. Chouchani et al.   Cell Metabolism

Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

(2016) Yong Hwan Han et al.   DIABETES

Mitochondrial H 2 O 2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm

(2016)   FREE RADICAL BIOLOGY AND MEDICINE

Increased obesity resistance and insulin sensitivity in mice lacking the isocitrate dehydrogenase 2 gene

(2016) Su Jeong Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Increased Energy Expenditure,Ucp1Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)

(2016) Kevin Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation

(2016) Christopher L. Riley et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

(2016) Edward T. Chouchani et al.   NATURE

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Evolution of Mitochondria as Signaling Organelles

(2015) Navdeep S. Chandel   Cell Metabolism

Covalent protein modification: the current landscape of residue-specific electrophiles

(2015) D Alexander Shannon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Expanding Landscape of the Thiol Redox Proteome

(2015) Jing Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Glutathione Decrement Drives Thermogenic Program In Adipose Cells

(2015) Daniele Lettieri Barbato et al.   Scientific Reports

Proteomic analysis of peptides tagged with dimedone and related probes

(2014) Pablo Martínez-Acedo et al.   JOURNAL OF MASS SPECTROMETRY

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

(2014) S.-H. Ro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sulfenic acid chemistry, detection and cellular lifetime

(2013) Vinayak Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial uncoupling prevents cold-induced oxidative stress: a case study using UCP1 knockout mice

(2013) A. Stier et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Fatty Acids are Key in 4-Hydroxy-2-Nonenal-Mediated Activation of Uncoupling Proteins 1 and 2

(2013) Elena A. Malingriaux et al.   PLoS One

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

ROS and Sympathetically Mediated Mitochondria Activation in Brown Adipose Tissue Contribute to Methamphetamine-Induced Hyperthermia

(2013) Manuel Sanchez-Alavez et al.   Frontiers in Endocrinology

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Mitochondrial redox signalling at a glance

(2012) Yvonne Collins et al.   JOURNAL OF CELL SCIENCE

Free radicals and antioxidants: updating a personal view

(2012) Barry Halliwell   NUTRITION REVIEWS

Mitochondria-Targeted Small Molecule Therapeutics and Probes

(2011) Robin A.J. Smith et al.   ANTIOXIDANTS & REDOX SIGNALING

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

Nrf2 Represses FGF21 During Long-Term High-Fat Diet-Induced Obesity in Mice

(2011) D. V. Chartoumpekis et al.   DIABETES

Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics

(2011) Ryan J. Mailloux et al.   FASEB JOURNAL

Glutathione Depletion Prevents Diet-Induced Obesity and Enhances Insulin Sensitivity

(2011) Hannes M. Findeisen et al.   Obesity

Lipid metabolism and body composition in Gclm(−/−) mice

(2011) Eric L. Kendig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Proteomic approaches to the characterization of protein thiol modification

(2010) Edward T Chouchani et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

(2010) Jingbo Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

(2009) Sergio Rodriguez-Cuenca et al.   FREE RADICAL BIOLOGY AND MEDICINE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology