Topical mevastatin promotes wound healing by inhibiting the transcription factor c-Myc via the glucocorticoid receptor and the long non-coding RNA Gas5

Opioids’ Effect on Healing of Venous Leg Ulcers

(2017) Ingrid Herskovitz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Stress Signals, Mediated by Membranous Glucocorticoid Receptor, Activate PLC/PKC/GSK-3β/β-catenin Pathway to Inhibit Wound Closure

(2017) Ivan Jozic et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A bioengineered living cell construct activates an acute wound healing response in venous leg ulcers

(2017) Rivka C. Stone et al.   Science Translational Medicine

Skin Metabolite, Farnesyl Pyrophosphate, Regulates Epidermal Response to Inflammation, Oxidative Stress, and Migration

(2016) Irena Pastar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Biology and Biomarkers for Wound Healing

(2016) Linsey E. Lindley et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Statins may be associated with six-week diabetic foot ulcer healing

(2016) Joshua D. Fox et al.   WOUND REPAIR AND REGENERATION

Integrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functions

(2016) Liang Liang et al.   WOUND REPAIR AND REGENERATION

The role of mitochondria in statin-induced myopathy

(2015) Maria Apostolopoulou et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Statin intolerance – an attempt at a unified definition. Position paper from an International Lipid Expert Panel

(2015) Maciej Banach et al.   Expert Opinion On Drug Safety

Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research

(2015) Lisa Gould et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin

(2015) Horacio A. Ramirez et al.   PLoS One

Simvastatin as a novel therapeutic agent for venous ulcers: a randomized, double-blind, placebo-controlled trial

(2014) M.T.P. Evangelista et al.   BRITISH JOURNAL OF DERMATOLOGY

Statins and the Risk of Diabetes: Evidence From a Large Population-Based Cohort Study

(2014) Giovanni Corrao et al.   DIABETES CARE

Stressing the Steroids in Skin: Paradox or Fine-Tuning?

(2014) Ivan Jozic et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Application of New Cholesterol Guidelines to a Population-Based Sample

(2014) Michael J. Pencina et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Long Non-Coding RNA GAS5 Cooperates with the Eukaryotic Translation Initiation Factor 4E to Regulate c-Myc Translation

(2014) Guangzhen Hu et al.   PLoS One

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Clinical application of growth factors and cytokines in wound healing

(2014) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

Deregulation of epidermal stem cell niche contributes to pathogenesis of nonhealing venous ulcers

(2014) Olivera Stojadinovic et al.   WOUND REPAIR AND REGENERATION

Epithelialization in Wound Healing: A Comprehensive Review

(2014) Irena Pastar et al.   Advances in Wound Care

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

Quality assessment of tissue specimens for studies of diabetic foot ulcers

(2013) Olivera Stojadinovic et al.   EXPERIMENTAL DERMATOLOGY

Interactions of Methicillin Resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in Polymicrobial Wound Infection

(2013) Irena Pastar et al.   PLoS One

Topical Simvastatin Accelerates Wound Healing in Diabetes by Enhancing Angiogenesis and Lymphangiogenesis

(2012) Jun Asai et al.   AMERICAN JOURNAL OF PATHOLOGY

A statin-regulated microRNA represses human c-Myc expression and function

(2012) Apana A. L. Takwi et al.   EMBO Molecular Medicine

Induction of Specific MicroRNAs Inhibits Cutaneous Wound Healing

(2012) Irena Pastar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of let-7i is associated with Toll-like receptor 4 signal in coronary artery disease: Effect of statins on let-7i and Toll-like receptor 4 signal

(2011) Mamoru Satoh et al.   IMMUNOBIOLOGY

Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury

(2011) Sasa Vukelic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statistical approach for avoiding pseudoreplication and increasing power in wound-healing studies

(2011) William G. Haag et al.   WOUND REPAIR AND REGENERATION

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

Farnesyl Pyrophosphate Inhibits Epithelialization and Wound Healing through the Glucocorticoid Receptor

(2009) Sasa Vukelic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Sustained Release of Vascular Endothelial Growth Factor in Accelerating Experimental Diabetic Healing

(2009) Harold Brem et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effect of Pravastatin on Experimental Diabetic Wound Healing

(2009) Tereze Laing et al.   JOURNAL OF SURGICAL RESEARCH

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Diabetic foot ulcer burden may be modified by high-dose atorvastatin: A 6-month randomized controlled pilot trial

(2009) Odd Erik JOHANSEN et al.   Journal of Diabetes

HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis

(2008) Veela B. Mehta et al.   GROWTH FACTORS

Deregulation of keratinocyte differentiation and activation: a hallmark of venous ulcers

(2008) Olivera Stojadinovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes

(2008) Alessandra Bitto et al.   PHARMACOLOGICAL RESEARCH

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION