Iron transport proteins: Gateways of cellular and systemic iron homeostasis

Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse

(2016) Ali Shawki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

(2016) Susanna Canali et al.   BLOOD

Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2

(2016) Izumi Yanatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese

(2015) Ali Shawki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Macrophages and iron trafficking at the birth and death of red cells

(2015) T. Korolnek et al.   BLOOD

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

(2015) Supak Jenkitkasemwong et al.   Cell Metabolism

Prion protein functions as a ferrireductase partner for ZIP14 and DMT1

(2015) Ajai K. Tripathi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation

(2015) C. Fillebeen et al.   HAEMATOLOGICA

Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation

(2015) C. Fillebeen et al.   HAEMATOLOGICA

Chaperone protein involved in transmembrane transport of iron

(2014) Izumi Yanatori et al.   BIOCHEMICAL JOURNAL

Heme Exporter FLVCR1a Regulates Heme Synthesis and Degradation and Controls Activity of Cytochromes P450

(2014) Francesca Vinchi et al.   GASTROENTEROLOGY

Anemia of Inflammation

(2014) Elizabeta Nemeth et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

The Multicopper Ferroxidase Hephaestin Enhances Intestinal Iron Absorption in Mice

(2014) Brie K. Fuqua et al.   PLoS One

Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc

(2013) Colin J. Mitchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

HRG1 Is Essential for Heme Transport from the Phagolysosome of Macrophages during Erythrophagocytosis

(2013) Carine White et al.   Cell Metabolism

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

(2013) H. Nam et al.   HAEMATOLOGICA

Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice

(2013) Chia-Yu Wang et al.   HEPATOLOGY

Each Member of the Poly-r(C)-binding Protein 1 (PCBP) Family Exhibits Iron Chaperone Activity toward Ferritin

(2013) Sebastien Leidgens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Iron Regulatory Proteins Control a Mucosal Block to Intestinal Iron Absorption

(2013) Bruno Galy et al.   Cell Reports

Plasma Clearance of Hemoglobin and Haptoglobin in Mice and Effect of CD163 Gene Targeting Disruption

(2012) Anders Etzerodt et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol

(2012) Y. Gottlieb et al.   HAEMATOLOGICA

Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice

(2012) Zhuzhen Zhang et al.   HEPATOLOGY

Substrate Profile and Metal-ion Selectivity of Human Divalent Metal-ion Transporter-1

(2012) Anthony C. Illing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

(2012) Deborah Chiabrando et al.   JOURNAL OF CLINICAL INVESTIGATION

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

(2011) Jorge J. Pinilla-Tenas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts

(2011) D.-L. Zhang et al.   BLOOD

Human mitochondrial ATP-binding cassette transporter ABCB10 is required for efficient red blood cell development

(2011) Leilei Tang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

(2010) W. Chen et al.   BLOOD

Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution

(2010) G. Kovtunovych et al.   BLOOD

Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption

(2010) Liviu Vanoaica et al.   Cell Metabolism

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

(2010) Antonello Pietrangelo   GASTROENTEROLOGY

A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression

(2009) De-Liang Zhang et al.   Cell Metabolism

Hepcidin targets ferroportin for degradation in hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport

(2009) Ajay Singh et al.   PLoS One

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

(2009) S. Soe-Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

(2009) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

(2008) Francesca Vinchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Haemopexin affects iron distribution and ferritin expression in mouse brain

(2008) Noemi Morello et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of Mitochondrial Iron Import through Differential Turnover of Mitoferrin 1 and Mitoferrin 2

(2008) P. N. Paradkar et al.   MOLECULAR AND CELLULAR BIOLOGY

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins

(2008) Abbhirami Rajagopal et al.   NATURE

A Cytosolic Iron Chaperone That Delivers Iron to Ferritin

(2008) H. Shi et al.   SCIENCE

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE