A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 geneCyp27b1essential for vitamin D3activation

Improved Screening Test for Idiopathic Infantile Hypercalcemia Confirms Residual Levels of Serum 24,25-(OH)2 D3 in Affected Patients

(2017) Martin Kaufmann et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Comparative analysis of nutritional guidelines for vitamin D

(2017) Roger Bouillon   Nature Reviews Endocrinology

Enhancer-derived RNA: A Primer

(2017) Feng Liu   GENOMICS PROTEOMICS & BIOINFORMATICS

Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells

(2016) Mark B. Meyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of the DistalTnfsf11RL-D2 Enhancer That Contributes to PTH-Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass Phenotype in Mice

(2016) Melda Onal et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Selective regulation of Mmp13 by 1,25(OH) 2 D 3 , PTH, and Osterix through distal enhancers

(2016) Mark B. Meyer et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D

(2016) Loan Nguyen-Yamamoto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A CTCF Code for 3D Genome Architecture

(2015) Michael H. Nichols et al.   CELL

A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and RenalCyp27b1andCyp24a1Expression in VDR Null Mice

(2015) Martin Kaufmann et al.   ENDOCRINOLOGY

The multiple sclerosis-associated regulatory variant rs10877013 affects expression of CYP27B1 and VDR under inflammatory or vitamin D stimuli

(2015) Mohamad Karaky et al.   Multiple Sclerosis Journal

The multiple sclerosis-associated regulatory variant rs10877013 affects expression of CYP27B1 and VDR under inflammatory or vitamin D stimuli

(2015) Mohamad Karaky et al.   Multiple Sclerosis Journal

Characterization of FGF23-Dependent Egr-1 Cistrome in the Mouse Renal Proximal Tubule

(2015) Anthony A. Portale et al.   PLoS One

The RUNX2 Cistrome in Osteoblasts

(2014) Mark B. Meyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 24,25-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD

(2014) Martin Kaufmann et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of the extrarenal CYP27B1-hydroxylase

(2014) John S. Adams et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice

(2013) Edwin C. Y. Chow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Cytochrome P450-mediated metabolism of vitamin D

(2013) Glenville Jones et al.   JOURNAL OF LIPID RESEARCH

Vitamin D and energy homeostasis—of mice and men

(2013) Roger Bouillon et al.   Nature Reviews Endocrinology

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase

(2012) J.S. Adams et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterizing Antibody Cross-reactivity for Immunoaffinity Purification of Analytes prior to Multiplexed Liquid Chromatography-Tandem Mass Spectrometry

(2012) T. J. Laha et al.   CLINICAL CHEMISTRY

Role of FGF23 in vitamin D and phosphate metabolism: Implications in chronic kidney disease

(2012) L. Darryl Quarles   EXPERIMENTAL CELL RESEARCH

Identification of a functional variant in theKIF5A-CYP27B1-METTL1-FAM119Blocus associated with multiple sclerosis

(2012) Antonio Alcina et al.   JOURNAL OF MEDICAL GENETICS

Distribution and regulation of the 25-hydroxyvitamin D3 1α-hydroxylase in human parathyroid glands

(2012) Cynthia S. Ritter et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism

(2012) L. Darryl Quarles   Nature Reviews Endocrinology

An encyclopedia of mouse DNA elements (Mouse ENCODE)

(2012) et al.   GENOME BIOLOGY

Rare variants in the CYP27B1 gene are associated with multiple sclerosis

(2011) Sreeram V. Ramagopalan et al.   ANNALS OF NEUROLOGY

Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D3 action

(2011) J. Wesley Pike et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

(2011) Glenville Jones et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation

(2011) Martin Kaufmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin D metabolism and function in the skin

(2011) Daniel D. Bikle   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Confirmation of association between multiple sclerosis and CYP27B1

(2010) Emilie Sundqvist et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases

(2010) M. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule

(2009) E. G. Farrow et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS