Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart

Phosphorylation of αB-crystallin: Role in stress, aging and patho-physiological conditions

(2016) Raman Bakthisaran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glucocorticoid activity detected by in vivo zebrafish assay and in vitro glucocorticoid receptor bioassay at environmental relevant concentrations

(2016) Qiyu Chen et al.   CHEMOSPHERE

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

(2016) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute stress is detrimental to heart regeneration in zebrafish

(2016) Pauline Sallin et al.   Open Biology

In vivo characterization of human myofibrillar myopathy genes in zebrafish

(2015) John B. Bührdel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent αAins-Crystallin Encode Activated Chaperones

(2015) Hanane A. Koteiche et al.   BIOCHEMISTRY

A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers

(2015) Scott P. Delbecq et al.   BIOCHEMISTRY

Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis

(2015) Erin Thornell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cardiac Transcriptome and Dilated Cardiomyopathy Genes in ZebrafishCLINICAL PERSPECTIVE

(2015) Yu-Huan Shih et al.   Circulation-Cardiovascular Genetics

Emerging Role for αB-Crystallin as a Therapeutic Agent: Pros and Cons

(2015) V.S. Reddy et al.   CURRENT MOLECULAR MEDICINE

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

A conserved role of αA-crystallin in the development of the zebrafish embryonic lens

(2015) Ping Zou et al.   EXPERIMENTAL EYE RESEARCH

Glucocorticoid signaling in the heart: A cardiomyocyte perspective

(2015) Robert H. Oakley et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cardiac Transcriptome and Dilated Cardiomyopathy Genes in ZebrafishCLINICAL PERSPECTIVE

(2015) Yu-Huan Shih et al.   Circulation-Cardiovascular Genetics

Crystallin-αB Regulates Skeletal Muscle Homeostasis via Modulation of Argonaute2 Activity

(2014) Ronald L. Neppl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell biological roles of αB-crystallin

(2014) Wilbert C. Boelens   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Acetylation of Lysine 92 Improves the Chaperone and Anti-apoptotic Activities of Human αB-Crystallin

(2013) Rooban B. Nahomi et al.   BIOCHEMISTRY

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cryoelectron Microscopy Analysis of Small Heat Shock Protein 16.5 (Hsp16.5) Complexes with T4 Lysozyme Reveals the Structural Basis of Multimode Binding

(2013) Jian Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids and foetal heart maturation; implications for prematurity and foetal programming

(2013) Eva A Rog-Zielinska et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection

(2013) Vigneshwaran Krishnamoorthy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Microarray Analyses of Glucocorticoid and Vitamin D3 Target Genes in Differentiating Cultured Human Podocytes

(2013) Xiwen Cheng et al.   PLoS One

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease

(2013) R. H. Oakley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulated structural transitions unleash the chaperone activity of  B-crystallin

(2013) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5

(2012) Hassane S. Mchaourab et al.   BIOCHEMISTRY

Embryo exposure to elevated cortisol level leads to cardiac performance dysfunction in zebrafish

(2012) Dinushan Nesan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish

(2012) Julie M. Hayes et al.   MOLECULAR BIOLOGY OF THE CELL

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

A novel CRYAB mutation resulting in multisystemic disease

(2011) Sabrina Sacconi et al.   NEUROMUSCULAR DISORDERS

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

(2011) S. Jehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of escape from nonsense-mediated mRNA decay of human  -globin transcripts with nonsense mutations in the first exon

(2011) G. Neu-Yilik et al.   RNA

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

(2011) Eman Basha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Infantile onset myofibrillar myopathy due to recessive CRYAB mutations

(2010) Katharine M.L. Forrest et al.   NEUROMUSCULAR DISORDERS

The Cellular Robustness by Genetic Redundancy in Budding Yeast

(2010) Jingjing Li et al.   PLoS Genetics

Deletion of54FLRAPSWF61Residues Decreases the Oligomeric Size and Enhances the Chaperone Function of αB-Crystallin

(2009) Puttur Santhoshkumar et al.   BIOCHEMISTRY

Structure and Mechanism of Protein Stability Sensors: Chaperone Activity of Small Heat Shock Proteins

(2009) Hassane S. Mchaourab et al.   BIOCHEMISTRY

Excess of Glucocorticoid Induces Cardiac Dysfunction via Activating Angiotensin II Pathway

(2009) Sreerupa Ghose Roy et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lengsin expression and function during zebrafish lens formation

(2008) Rachel L. Harding et al.   EXPERIMENTAL EYE RESEARCH

A Statistical Model for iTRAQ Data Analysis

(2008) Elizabeth G. Hill et al.   JOURNAL OF PROTEOME RESEARCH

Genome wide transcriptional profiling in breast cancer cells reveals distinct changes in hormone receptor target genes and chromatin modifying enzymes after proteasome inhibition

(2008) H. Karimi Kinyamu et al.   MOLECULAR CARCINOGENESIS

Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts

(2007) Ilka Pinz et al.   FASEB JOURNAL