TRIM24 protein promotes and TRIM32 protein inhibits cardiomyocyte hypertrophy via regulation of dysbindin protein levels

TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer

(2016) Anna C. Groner et al.   CANCER CELL

Tripartite motif 32 prevents pathological cardiac hypertrophy

(2016) L. Chen et al.   CLINICAL SCIENCE

The E3 ubiquitin ligase TRIM32 regulates myoblast proliferation by controlling turnover of NDRG2

(2015) Ekaterina I. Mokhonova et al.   HUMAN MOLECULAR GENETICS

Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling

(2015) Ashraf Yusuf Rangrez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice

(2015) Shiming Jiang et al.   JOURNAL OF HEPATOLOGY

The Schizophrenia-Related Protein Dysbindin-1A Is Degraded and Facilitates NF-Kappa B Activity in the Nucleus

(2015) Cheng Fu et al.   PLoS One

Clinical significance and biological roles of TRIM24 in human bladder carcinoma

(2015) Dongwei Xue et al.   TUMOR BIOLOGY

TRIM24 is upregulated in human gastric cancer and promotes gastric cancer cell growth and chemoresistance

(2015) Zhi-Feng Miao et al.   VIRCHOWS ARCHIV

E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis

(2014) Ju Liu et al.   CELL DEATH AND DIFFERENTIATION

Rare Variants in Genes Encoding MuRF1 and MuRF2 Are Modifiers of Hypertrophic Cardiomyopathy

(2014) Ming Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dysbindin-1C Is Required for the Survival of Hilar Mossy Cells and the Maturation of Adult Newborn Neurons in Dentate Gyrus

(2014) Hao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysbindin is a potent inducer of RhoA–SRF-mediated cardiomyocyte hypertrophy

(2014) Ashraf Yusuf Rangrez et al.   JOURNAL OF CELL BIOLOGY

Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation

(2014) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin-proteasome system and hereditary cardiomyopathies

(2014) Saskia Schlossarek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mice with cardiac-restricted overexpression of Myozap are sensitized to biomechanical stress and develop a protein-aggregate-associated cardiomyopathy

(2014) Derk Frank et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

TRIM24 Is a p53-Induced E3-Ubiquitin Ligase That Undergoes ATM-Mediated Phosphorylation and Autodegradation during DNA Damage

(2014) A. K. Jain et al.   MOLECULAR AND CELLULAR BIOLOGY

Knockdown of Tripartite Motif Containing 24 by Lentivirus Suppresses Cell Growth and Induces Apoptosis in Human Colorectal Cancer Cells

(2014) Jianwei Wang et al.   ONCOLOGY RESEARCH

TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation

(2013) A-L Hillje et al.   Cell Death & Disease

Human Molecular Genetic and Functional Studies Identify TRIM63 , Encoding Muscle RING Finger Protein 1, as a Novel Gene for Human Hypertrophic Cardiomyopathy

(2012) Suet Nee Chen et al.   CIRCULATION RESEARCH

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

(2012) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

(2012) Sarah Nicklas et al.   PLoS One

The Ubiquitin Ligase MuRF1 Protects Against Cardiac Ischemia/Reperfusion Injury by Its Proteasome-Dependent Degradation of Phospho-c-Jun

(2011) Hui-Hua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Dysbindin-Containing Complexes and their Proposed Functions in Brain: From Zero to (too) Many in a Decade

(2011) Cristina A Ghiani et al.   ASN Neuro

TRIM32 Protein Sensitizes Cells to Tumor Necrosis Factor (TNFα)-induced Apoptosis via Its RING Domain-dependent E3 Ligase Activity against X-linked Inhibitor of Apoptosis (XIAP)

(2011) Yeung Sook Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Biology of the BLOC-1 Complex Subunit Dysbindin, a Schizophrenia Susceptibility Gene

(2011) Ariana P. Mullin et al.   MOLECULAR NEUROBIOLOGY

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

(2011) X Ma et al.   MOLECULAR PSYCHIATRY

Reduced Rate of Neural Differentiation in the Dentate Gyrus of Adult Dysbindin Null (Sandy) Mouse

(2011) Naomi Nihonmatsu-Kikuchi et al.   PLoS One

Myozap, a Novel Intercalated Disc Protein, Activates Serum Response Factor–Dependent Signaling and Is Required to Maintain Cardiac Function In Vivo

(2010) Thalia S. Seeger et al.   CIRCULATION RESEARCH

Nucleocytoplasmic Shuttling of Dysbindin-1, a Schizophrenia-related Protein, Regulates Synapsin I Expression

(2010) Erkang Fei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM24 links a non-canonical histone signature to breast cancer

(2010) Wen-Wei Tsai et al.   NATURE

Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis

(2010) M Hörnle et al.   ONCOGENE

Cardiac Muscle Ring Finger-1 Increases Susceptibility to Heart Failure In Vivo

(2009) Monte S. Willis et al.   CIRCULATION RESEARCH

Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component

(2009) Elena Kudryashova et al.   HUMAN MOLECULAR GENETICS

TRIM32 is an E3 ubiquitin ligase for dysbindin

(2009) Matthew Locke et al.   HUMAN MOLECULAR GENETICS

Trim24 targets endogenous p53 for degradation

(2009) Kendra Allton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Expression Pattern in Biomechanically Stretched Cardiomyocytes

(2007) Derk Frank et al.   HYPERTENSION