Hypoxia reduces HNF4α/MODY1 protein expression in pancreatic β-cells by activating AMP-activated protein kinase

An evolutionarily conserved pathway controls proteasome homeostasis

(2016) Adrien Rousseau et al.   NATURE

Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation

(2015) Jianwen Wei et al.   CELL

SIRT7 Controls Hepatic Lipid Metabolism by Regulating the Ubiquitin-Proteasome Pathway

(2014) Tatsuya Yoshizawa et al.   Cell Metabolism

Moderate Hypoxia Induces β-Cell Dysfunction with HIF-1–Independent Gene Expression Changes

(2014) Yoshifumi Sato et al.   PLoS One

Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells

(2012) Yoshifumi Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose-Induced O2 Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells

(2012) Mohammed Bensellam et al.   PLoS One

Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP

(2012) X Zheng et al.   Cell Death & Disease

AMP-Activated Protein Kinase Regulates E3 Ligases in Rodent Heart

(2011) Kedryn K. Baskin et al.   CIRCULATION RESEARCH

Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretionin Vitro

(2011) Yoshifumi Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Glucose Deprivation Regulates K ATP Channel Trafficking via AMP-Activated Protein Kinase in Pancreatic β-Cells

(2009) Ajin Lim et al.   DIABETES

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic   cells

(2008) J. Zehetner et al.   GENES & DEVELOPMENT

Islet Oxygen Consumption and Insulin Secretion Tightly Coupled to Calcium Derived from L-type Calcium Channels but Not from the Endoplasmic Reticulum

(2008) Merle Gilbert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of HNF-4α (MODY1), HNF-1β (MODY5), and HNF-1α (MODY3) proteins in the developing mouse pancreas

(2007) Takao Nammo et al.   GENE EXPRESSION PATTERNS