Selective export of autotaxin from the endoplasmic reticulum

Drosophila p24 and Sec22 regulate Wingless trafficking in the early secretory pathway

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ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity

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Nerve Growth Factor (NGF) Regulates Activity of Nuclear Factor of Activated T-cells (NFAT) in Neurons via the Phosphatidylinositol 3-Kinase (PI3K)-Akt-Glycogen Synthase Kinase 3β (GSK3β) Pathway

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The Autotaxin-LPA Axis Emerges as a Novel Regulator of Lymphocyte Homing and Inflammation

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Transport of glycosylphosphatidylinositol-anchored proteins from the endoplasmic reticulum

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Involvement of autotaxin/lysophosphatidic acid signaling in obesity and impaired glucose homeostasis

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Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: A focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays

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Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration

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Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

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Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

(2012) T. Sangai et al.   CLINICAL CANCER RESEARCH

The PI3K/AKT/mTOR Pathway as a Therapeutic Target in Endometrial Cancer

(2012) B. M. Slomovitz et al.   CLINICAL CANCER RESEARCH

A 3D view of autotaxin

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Autotaxin and LPA receptor signaling in cancer

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p24 proteins are required for secretion of Wnt ligands

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Transcriptional Regulation of TMP21 by NFAT

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Location, location, location: a crystal-clear view of autotaxin saturating LPA receptors

(2011) Adel Tabchy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

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Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors

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Protein Sorting Receptors in the Early Secretory Pathway

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Regulation of coat assembly—sorting things out at the ER

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ATX expression and LPA signalling are vital for the development of the nervous system

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Selective export of human GPI-anchored proteins from the endoplasmic reticulum

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The p24 family and selective transport processes at the ER-Golgi interface

(2009) Jeroen R.P.M. Strating et al.   BIOLOGY OF THE CELL

Roles of LPA in ovarian cancer development and progression

(2009) Tarah L Pua et al.   Future Oncology

Domain Interplay Mediated by an Essential Disulfide Linkage Is Critical for the Activity and Secretion of the Metastasis-promoting Enzyme Autotaxin

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Lipopolysaccharide induces autotaxin expression in human monocytic THP-1 cells

(2008) Song Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane

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Autotaxin (ATX): A multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties

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