Site-specificO-Glycosylation by PolypeptideN-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

(2016) Sumeet A. Khetarpal et al.   Cell Metabolism

The Parkinson's-disease-associated receptor GPR37 undergoes metalloproteinase-mediated N-terminal cleavage and ectodomain shedding

(2016) S. Orvokki Mattila et al.   JOURNAL OF CELL SCIENCE

Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

(2016) Marco Cavalli et al.   Lipids in Health and Disease

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses

(2016) Ulrich Eckhard et al.   MATRIX BIOLOGY

Metalloprotease cleavage of the N terminus of the orphan G protein–coupled receptor GPR37L1 reduces its constitutive activity

(2016) James L. J. Coleman et al.   Science Signaling

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

(2016) Peer-Hendrik Kuhn et al.   eLife

Metalloprotease cleavage of the N terminus of the orphan G protein–coupled receptor GPR37L1 reduces its constitutive activity

(2016) James L. J. Coleman et al.   Science Signaling

Advances in mass spectrometry driven O-glycoproteomics

(2015) Steven B. Levery et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Deconstruction of O-glycosylation--GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

(2015) K. T. Schjoldager et al.   EMBO REPORTS

Proteomic approaches to uncover MMP function

(2015) Pascal Schlage et al.   MATRIX BIOLOGY

Engineered CHO cells for production of diverse, homogeneous glycoproteins

(2015) Zhang Yang et al.   NATURE BIOTECHNOLOGY

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

(2015) Christoffer K. Goth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

(2014) Yun Kong et al.   GLYCOBIOLOGY

N-Glycan-dependent and -independent Quality Control of Human δ Opioid Receptor N-terminal Variants

(2014) Jarkko J. Lackman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

(2013) Catharina Steentoft et al.   EMBO JOURNAL

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality

(2013) Marko T. Boskovski et al.   NATURE

Site-specific protein O-glycosylation modulates proprotein processing — Deciphering specific functions of the large polypeptide GalNAc-transferase gene family

(2012) Katrine T.-B.G. Schjoldager et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Ectodomain shedding and ADAMs in development

(2012) S. Weber et al.   DEVELOPMENT

C5a receptor is cleaved by metalloproteases induced by sphingomyelinase D from Loxosceles spider venom

(2012) Carmen W. van den Berg et al.   IMMUNOBIOLOGY

LC–MS/MS Characterization of O-Glycosylation Sites and Glycan Structures of Human Cerebrospinal Fluid Glycoproteins

(2012) Adnan Halim et al.   JOURNAL OF PROTEOME RESEARCH

Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism

(2012) Kingsley Osuala et al.   PHYSIOLOGICAL GENOMICS

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

(2012) K. T.- B. G. Schjoldager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis

(2011) Brady K Atwood et al.   BMC GENOMICS

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family

(2011) E. P. Bennett et al.   GLYCOBIOLOGY

A Systematic Study of Site-specific GalNAc-typeO-Glycosylation Modulating Proprotein Convertase Processing

(2011) Katrine Ter-Borch Gram Schjoldager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

(2011) Catharina Steentoft et al.   NATURE METHODS

O-Glycosylation Modulates Proprotein Convertase Activation of Angiopoietin-like Protein 3

(2010) Katrine T.-B. G. Schjoldager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agonist-regulated Cleavage of the Extracellular Domain of Parathyroid Hormone Receptor Type 1

(2010) Christoph Klenk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human β1-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage

(2010) Anna E. Hakalahti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Mechanisms of Pharmacogenomic Effects of Genetic Variation within the Cardiac Adrenergic Network in Heart Failure

(2009) G. W. Dorn et al.   MOLECULAR PHARMACOLOGY

N-Glycan-mediated Quality Control in the Endoplasmic Reticulum Is Required for the Expression of Correctly Folded δ-Opioid Receptors at the Cell Surface

(2008) Piia M. H. Markkanen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY