Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216

Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells

(2015) Takashi Nojiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Profiling-based Data-mining for an Effective Chemical Combination to Induce Apoptosis of Cancer Cells

(2015) Motofumi Kumazoe et al.   Scientific Reports

Phosphodiesterase 5 inhibitor acts as a potent agent sensitizing acute myeloid leukemia cells to 67-kDa laminin receptor-dependent apoptosis

(2013) Motofumi Kumazoe et al.   FEBS LETTERS

The LDL to HDL Cholesterol Ratio as a Valuable Tool to Evaluate Coronary Heart Disease Risk

(2013) Maria Luz Fernandez et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue

(2013) Guenther Boden et al.   Obesity

Green Tea Extract Containing a Highly Absorbent Catechin Prevents Diet-Induced Lipid Metabolism Disorder

(2013) Takashi Suzuki et al.   Scientific Reports

Green tea polyphenol epigallocatechin-3-gallate inhibits TLR4 signaling through the 67-kDa laminin receptor on lipopolysaccharide-stimulated dendritic cells

(2012) Eui-Baek Byun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Green tea polyphenol EGCG induces lipid-raft clustering and apoptotic cell death by activating protein kinase Cδ and acid sphingomyelinase through a 67 kDa laminin receptor in multiple myeloma cells

(2012) Shuntaro Tsukamoto et al.   BIOCHEMICAL JOURNAL

(−)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells

(2012) Jieliang Li et al.   Journal of Neuroinflammation

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice

(2012) Zhi-Hong Yang et al.   Diabetology & Metabolic Syndrome

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

(2011) Thérèse Keravis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Low-Grade Hypothalamic Inflammation Leads to Defective Thermogenesis, Insulin Resistance, and Impaired Insulin Secretion

(2011) Ana Paula Arruda et al.   ENDOCRINOLOGY

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

(2011) Min Song et al.   Journal of Neuroinflammation

Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet

(2011) Brante P. Sampey et al.   Obesity

TLR4 Signaling Inhibitory Pathway Induced by Green Tea Polyphenol Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor

(2010) E. Hong Byun et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptors: linking inflammation to metabolism

(2010) A. Christine Könner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia

(2009) Dario A. Gutierrez et al.   Current Diabetes Reports

Phase I Trial of Daily Oral Polyphenon E in Patients With Asymptomatic Rai Stage 0 to II Chronic Lymphocytic Leukemia

(2009) Tait D. Shanafelt et al.   JOURNAL OF CLINICAL ONCOLOGY

Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells

(2008) Matthew Hotston et al.   ASIAN JOURNAL OF ANDROLOGY

The effect of dietary cholesterol on macrophage accumulation in adipose tissue: implications for systemic inflammation and atherosclerosis

(2008) Savitha Subramanian et al.   CURRENT OPINION IN LIPIDOLOGY

SREBPs: physiology and pathophysiology of the SREBP family

(2008) Hitoshi Shimano   FEBS Journal