Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice

Plk1 inhibition enhances the efficacy of gemcitabine in human pancreatic cancer

(2016) Jie Li et al.   CELL CYCLE

Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics

(2016) Rosie Elizabeth Ann Gutteridge et al.   MOLECULAR CANCER THERAPEUTICS

Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1)

(2015) Zhiguo Li et al.   CELL CYCLE

Development of Bifunctional Inhibitors of Polo-Like Kinase 1 with Low-Nanomolar Activities Against the Polo-Box Domain

(2015) Andrej Scharow et al.   CHEMBIOCHEM

Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment

(2015) Xiaoqi Liu   Translational Oncology

Recent Advances and New Strategies in Targeting Plk1 for Anticancer Therapy

(2015) Kyung S. Lee et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Polo-like kinase-1 in DNA damage response

(2014) Sun-Yi Hyun et al.   BMB Reports

Plk1 Inhibition Enhances the Efficacy of Androgen Signaling Blockade in Castration-Resistant Prostate Cancer

(2014) Z. Zhang et al.   CANCER RESEARCH

Thoughts on the current assessment of Polo-like kinase inhibitor drug discovery

(2014) Klaus Strebhardt et al.   Expert Opinion on Drug Discovery

Inhibition of Polo-like Kinase 1 (Plk1) Enhances the Antineoplastic Activity of Metformin in Prostate Cancer

(2014) Chen Shao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State

(2014) Z. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The Role of Polo-like Kinase 1 in Carcinogenesis: Cause or Consequence?

(2013) B. D. Cholewa et al.   CANCER RESEARCH

Plk1-dependent microtubule dynamics promotes androgen receptor signaling in prostate cancer

(2013) Xianzeng Hou et al.   PROSTATE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Centrosomes, chromosome instability (CIN) and aneuploidy

(2012) Benjamin D Vitre et al.   CURRENT OPINION IN CELL BIOLOGY

Plk1 Phosphorylation of Orc2 and Hbo1 Contributes to Gemcitabine Resistance in Pancreatic Cancer

(2012) B. Song et al.   MOLECULAR CANCER THERAPEUTICS

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Beyond ATM: The protein kinase landscape of the DNA damage response

(2011) Ariel Bensimon et al.   FEBS LETTERS

Cytokinesis, ploidy and aneuploidy

(2011) Benjamin Lacroix et al.   JOURNAL OF PATHOLOGY

Mitotic catastrophe: a mechanism for avoiding genomic instability

(2011) Ilio Vitale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Substrates of Mitotic Kinases

(2011) L. N. Johnson   Science Signaling

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

(2011) Monika Raab et al.   Nature Communications

Polo-Like Kinase 1 as Predictive Marker and Therapeutic Target for Radiotherapy in Rectal Cancer

(2010) Franz Rödel et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms of aneuploidy

(2010) Duane A Compton   CURRENT OPINION IN CELL BIOLOGY

Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery

(2010) X Shawn Liu et al.   EMBO REPORTS

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Plk1-mediated Phosphorylation of Topors Regulates p53 Stability

(2009) Xiaoming Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY