Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling

GPR56/ADGRG1 Activation Promotes Melanoma Cell Migration via NTF Dissociation and CTF-Mediated Gα 12/13 /RhoA Signaling

(2017) Nien-Yi Chiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist

(2016) Caroline Wilde et al.   FASEB JOURNAL

Adhesion G Protein-Coupled Receptor G1 (ADGRG1/GPR56) and Pancreatic β-Cell Function

(2016) Pontus Dunér et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

(2016) Gin-Wen Chang et al.   Cell Reports

Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2

(2015) Lilian M. Demberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

(2015) Miriam C. Peeters et al.   CELLULAR SIGNALLING

Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)

(2015) Ayush Kishore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bilateral Frontoparietal Polymicrogyria: A Novel GPR56 Mutation and an Unusual Phenotype

(2015) Armanda Passas et al.   NEUROPEDIATRICS

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development

(2015) Stefanie Giera et al.   Nature Communications

The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation

(2015) Nicole Scholz et al.   Cell Reports

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

(2014) Ines Liebscher et al.   Annals of the New York Academy of Sciences

Chaperoning G Protein-Coupled Receptors: From Cell Biology to Therapeutics

(2014) Ya-Xiong Tao et al.   ENDOCRINE REVIEWS

Constitutive GαiCoupling Activity of Very Large G Protein-coupled Receptor 1 (VLGR1) and Its Regulation by PDZD7 Protein

(2014) Qiao-Xia Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism for Adhesion G Protein-Coupled Receptor GPR56-Mediated RhoA Activation Induced By Collagen III Stimulation

(2014) Rong Luo et al.   PLoS One

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

(2014) J. P. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle developmentin vivo

(2013) Melissa P. Wu et al.   FEBS Journal

Brain-specific Angiogenesis Inhibitor-1 Signaling, Regulation, and Enrichment in the Postsynaptic Density

(2013) Jason R. Stephenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56

(2013) Y Saito et al.   LEUKEMIA

GPR56 Functions Together with α3β1 Integrin in Regulating Cerebral Cortical Development

(2013) Sung-Jin Jeong et al.   PLoS One

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Matching structure with function: the GAIN domain of Adhesion-GPCR and PKD1-like proteins

(2013) Simone Prömel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Comparative phosphoproteomic analysis of neonatal and adult murine brain

(2012) Tapasree Goswami et al.   PROTEOMICS

GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

(2011) L. Yang et al.   CANCER RESEARCH

LPA Receptor Heterodimerizes with CD97 to Amplify LPA-Initiated RHO-Dependent Signaling and Invasion in Prostate Cancer Cells

(2011) Y. Ward et al.   CANCER RESEARCH

The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling Activity

(2011) Kevin J. Paavola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disease-associated GPR56 Mutations Cause Bilateral Frontoparietal Polymicrogyria via Multiple Mechanisms

(2011) Nien-Yi Chiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific expression of GPR56 by human cytotoxic lymphocytes

(2011) Yen-Ming Peng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex

(2010) Nadia Bahi-Buisson et al.   BRAIN

The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels

(2010) A Singh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing

(2010) Daisuke Okajima et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

GPR56-Regulated Granule Cell Adhesion Is Essential for Rostral Cerebellar Development

(2009) S. Koirala et al.   JOURNAL OF NEUROSCIENCE

Orphan G Protein-coupled Receptor GPR56 Regulates Neural Progenitor Cell Migration via a Gα12/13 and Rho Pathway

(2008) Tokuichi Iguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GPS 2.0, a Tool to Predict Kinase-specific Phosphorylation Sites in Hierarchy

(2008) Yu Xue et al.   MOLECULAR & CELLULAR PROTEOMICS