Pharmacokinetics/pharmacodynamics of systemically administered polymyxin B against Klebsiella pneumoniae in mouse thigh and lung infection models

In VivoPharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model

(2016) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics/Pharmacodynamics of Pulmonary Delivery of Colistin against Pseudomonas aeruginosa in a Mouse Lung Infection Model

(2016) Yu-Wei Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Agents of Last Resort

(2016) Keith S. Kaye et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

A pharmacokinetic–pharmacodynamic (PKPD) model based onin vitrotime–kill data predicts thein vivoPK/PD index of colistin

(2016) David D. Khan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacokinetics and Penetration of Ceftazidime and Avibactam into Epithelial Lining Fluid in Thigh- and Lung-Infected Mice

(2015) Johanna Berkhout et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Assessment of Minocycline and Polymyxin B Combination against Acinetobacter baumannii

(2015) Dana R. Bowers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Updated US and European Dose Recommendations for Intravenous Colistin: How Do They Perform?

(2015) Roger L. Nation et al.   CLINICAL INFECTIOUS DISEASES

The Role of Aerosolized Colistin in the Treatment of Ventilator-Associated Pneumonia

(2015) Antonis Valachis et al.   CRITICAL CARE MEDICINE

Differences in potency and categorical agreement between colistin and polymyxin B when testing 15,377 clinical strains collected worldwide

(2015) Helio S. Sader et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

(2015) Roger L Nation et al.   LANCET INFECTIOUS DISEASES

Comparison of Intrapulmonary and Systemic Pharmacokinetics of Colistin Methanesulfonate (CMS) and Colistin after Aerosol Delivery and Intravenous Administration of CMS in Critically Ill Patients

(2014) Matthieu Boisson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pulmonary and Systemic Pharmacokinetics of Inhaled and Intravenous Colistin Methanesulfonate in Cystic Fibrosis Patients: Targeting Advantage of Inhalational Administration

(2014) S. W. S. Yapa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 2. Colistin

(2014) Aline Vidal Lacerda Gontijo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin and Polymyxin B: Peas in a Pod, or Chalk and Cheese?

(2014) R. L. Nation et al.   CLINICAL INFECTIOUS DISEASES

Colistin for the treatment of ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: A systematic review and meta-analysis

(2014) Wan-Jie Gu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Development and validation of a liquid chromatography–mass spectrometry assay for polymyxin B in bacterial growth media

(2014) Soon-Ee Cheah et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Population Pharmacokinetics of Colistin Methanesulfonate in Rats: Achieving Sustained Lung Concentrations of Colistin for Targeting Respiratory Infections

(2013) Shalini W. S. Yapa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens

(2013) Ana M. Sandri et al.   CLINICAL INFECTIOUS DISEASES

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae

(2013) Tony Velkov et al.   Innate Immunity

A validated ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of polymyxin B in mouse serum and epithelial lining fluid: application to pharmacokinetic studies

(2013) J. He et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In VivoPharmacokinetics/Pharmacodynamics of Colistin and Imipenem in Pseudomonas aeruginosa Biofilm Infection

(2012) Wang Hengzhuang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of inhaled colistimethate sodium (CMS) in mechanically ventilated critically ill patients

(2012) Zoe E. Athanassa et al.   INTENSIVE CARE MEDICINE

Performance and Robustness of the Monte Carlo Importance Sampling Algorithm Using Parallelized S-ADAPT for Basic and Complex Mechanistic Models

(2011) Jurgen B. Bulitta et al.   AAPS Journal

Development of a New Pre- and Post-Processing Tool (SADAPT-TRAN) for Nonlinear Mixed-Effects Modeling in S-ADAPT

(2011) Jurgen Bernd Bulitta et al.   AAPS Journal

Aerosol Therapy with Colistin Methanesulfonate: a Biopharmaceutical Issue Illustrated in Rats

(2010) S. Marchand et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model

(2010) P. J. Bergen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa

(2010) Qin Lu et al.   INTENSIVE CARE MEDICINE

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

(2008) E. Llobet et al.   MICROBIOLOGY-SGM