Preclinical testing of a broad-spectrum antimicrobial endotracheal tube coated with an innate immune synthetic mimic

The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro

(2017) Yu Luo et al.   Frontiers in Microbiology

Pseudomonas aeruginosa Ventilator-Associated Pneumonia Induces Lung Injury through TNF-α/c-Jun NH2-Terminal Kinase Pathways

(2017) Ying-Wei Yang et al.   PLoS One

Polymicrobial Ventilator-Associated Pneumonia: Fighting In Vitro Candida albicans-Pseudomonas aeruginosa Biofilms with Antifungal-Antibacterial Combination Therapy

(2017) Maria E. Rodrigues et al.   PLoS One

Detection ofmcr-1among Escherichia coli Clinical Isolates Collected Worldwide as Part of the SENTRY Antimicrobial Surveillance Program in 2014 and 2015

(2016) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial proteins and peptides in human lung diseases: A friend and foe partnership with host proteases

(2016) Fabien Lecaille et al.   BIOCHIMIE

Preventing Ventilator-Associated Infections

(2016) Avani Mehta et al.   CLINICS IN CHEST MEDICINE

Antifungal use in immunocompetent, critically ill patients with pneumonia does not improve clinical outcomes

(2016) Meagan Griffin et al.   HEART & LUNG

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids

(2016) Ruan Fourie et al.   Frontiers in Physiology

Candidacidal Activity of Selected Ceragenins and Human Cathelicidin LL-37 in Experimental Settings Mimicking Infection Sites

(2016) Bonita Durnaś et al.   PLoS One

The endotracheal tube microbiome associated with Pseudomonas aeruginosa or Staphylococcus epidermidis

(2016) An Hotterbeekx et al.   Scientific Reports

Colistin Resistance Mechanisms in Klebsiella pneumoniae Strains from Taiwan

(2015) Yi-Hsiang Cheng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fetal and early neonatal interleukin-6 response

(2015) Claudio Chiesa et al.   CYTOKINE

CSA-131, a ceragenin active against colistin-resistant Acinetobacter baumannii and Pseudomonas aeruginosa clinical isolates

(2015) Xavier Vila-Farrés et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Endotracheal Tubes: Old and New

(2014) C. F. Haas et al.   Respiratory Care

Interactions in multispecies biofilms: do they actually matter?

(2014) Mette Burmølle et al.   TRENDS IN MICROBIOLOGY

Immune modulation by multifaceted cationic host defense (antimicrobial) peptides

(2013) Ashley L Hilchie et al.   Nature Chemical Biology

Use of Silver in the Prevention and Treatment of Infections: Silver Review

(2013) Amani D. Politano et al.   Surgical Infections

Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation

(2012) Katheryn E. Nathe et al.   PEDIATRIC RESEARCH

Molecular Analysis of Microbial Communities in Endotracheal Tube Biofilms

(2011) Scott Cairns et al.   PLoS One

Review: Defensins and cathelicidins in lung immunity

(2010) Tesfaldet Tecle et al.   Innate Immunity

Ceragenins: Cholic Acid-Based Mimics of Antimicrobial Peptides

(2008) Xin-Zhong Lai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Streptococcus mutans biofilm changes surface-topography of resin composites

(2007) Nurit Beyth et al.   DENTAL MATERIALS