期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 57, 期 3, 页码 697-703出版社
IOS PRESS
DOI: 10.3233/JAD-161170
关键词
APP Ala713Thr; familial Alzheimer's disease; florbetapir PET; frontotemporal dementia
资金
- Italian Ministry of Health [RF-2010-2319722]
- Fondazione Cassa di Risparmio di Pistoia e Pescia [2014.0365]
According to the literature, the APP Ala713Thr mutation is associated with Alzheimer's disease and cerebral amyloid angiopathy. We describe a case of dementia clinically compatible with frontotemporal dementia in an APP Ala713Thr mutation carrier in which both [F-18] Florbetapir PET uptake and A beta(1-42) cerebrospinal fluid levels were normal. Further evidences are required to establish if this association is only incidental.
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