Oxidative stress parameters and serum magnesium levels in patients with seasonal allergic conjunctivitis

Objective: To evaluate oxidative stress parameters and serum magnesium (Mg) levels in patients with seasonal allergic conjunctivitis (SAC) during the pollen season.Methods: This observational cross-sectional study involved 35 patients with SAC without any other ocular and systemic diseases, and 38 consecutive, age- and sex-matched healthy subjects. Serum malondialdehyde (MDA), adjusted ischemia modified albumin (IMA), and Mg levels were quantified, and the results were compared between the groups.Results: No significant differences were found between the groups with respect to age (p=0.416) and sex (p=0.362). Serum MDA and adjusted IMA levels of the subjects with SAC (69.547.71 M and 0.74 +/- 0.39 ABSU) were significantly higher than the control group (64.61 +/- 5.89 M and 0.57 +/- 0.19 ABSU) (p=0.002 and p=0.025, respectively). There was no significant difference for serum Mg levels between the groups (p=0.177).Conclusion: We demonstrated higher levels of oxidative stress parameters in patients with SAC compared to the control group, which imply a possible role of oxidative stress in the pathogenesis of SAC.