Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue

Innovation in the pharmaceutical industry: New estimates of R&D costs

(2016) Joseph A. DiMasi et al.   JOURNAL OF HEALTH ECONOMICS

Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans

(2015) Mark J.W. Hanssen et al.   DIABETES

Genetic and functional characterization of clonally derived adult human brown adipocytes

(2015) Kosaku Shinoda et al.   NATURE MEDICINE

Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance

(2014) Mark J. W. Hanssen et al.   DIABETOLOGIA

Comparative gene array analysis of progenitor cells from human paired deep neck and subcutaneous adipose tissue

(2014) D. Tews et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Feeding the heat on brown fat

(2013) Dyan Sellayah et al.   Annals of the New York Academy of Sciences

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Presence of Brown Adipocytes in Retroperitoneal Fat From Patients With Benign Adrenal Tumors: Relationship With Outdoor Temperature

(2013) Matthias Johannes Betz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of orexin A on GLUT4 expression and lipid content via MAPK signaling in 3T3-L1 adipocytes

(2013) Yang Shen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Mechanisms underlying obesity resistance associated with high spontaneous physical activity

(2013) J.A. Teske et al.   NEUROSCIENCE

Brain orexin promotes obesity resistance

(2012) Catherine Kotz et al.   Annals of the New York Academy of Sciences

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Diagnosing the decline in pharmaceutical R&D efficiency

(2012) Jack W. Scannell et al.   NATURE REVIEWS DRUG DISCOVERY

A Modified Protocol to Maximize Differentiation of Human Preadipocytes and Improve Metabolic Phenotypes

(2012) Mi-Jeong Lee et al.   Obesity

Orexin receptor-1 mediates brown fat developmental differentiation

(2012) Dyan Sellayah et al.   Adipocyte

Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function

(2011) Dyan Sellayah et al.   Cell Metabolism

Orexin A stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3T3-L1 adipocytes and isolated primary rat adipocytes

(2011) M. Skrzypski et al.   DIABETOLOGIA

Inducible Brown Adipogenesis of Supraclavicular Fat in Adult Humans

(2011) Paul Lee et al.   ENDOCRINOLOGY

An Orexinergic Projection from Perifornical Hypothalamus to Raphe Pallidus Increases Rat Brown Adipose Tissue Thermogenesis

(2011) D. Tupone et al.   JOURNAL OF NEUROSCIENCE

Genomic organization and regulation of the human orexin (hypocretin) receptor 2 gene: identification of alternative promoters

(2010) Jing Chen et al.   BIOCHEMICAL JOURNAL

Acute Stimulation of White Adipocyte Respiration by PKA-Induced Lipolysis

(2010) E. Yehuda-Shnaidman et al.   DIABETES

Changes of orexin A plasma levels in girls with anorexia nervosa during eight weeks of realimentation

(2010) Jiri Bronsky et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Enhanced Orexin Receptor-2 Signaling Prevents Diet-Induced Obesity and Improves Leptin Sensitivity

(2009) Hiromasa Funato et al.   Cell Metabolism

Relation of adipose tissue to metabolic flexibility

(2008) Lauren M. Sparks et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Toxicity testing in the 21st century: A vision and a strategy

(2007) Steven Gibb   REPRODUCTIVE TOXICOLOGY