NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction

NLRP3 inflammasome activation contributes to long-term behavioral alterations in mice injected with lipopolysaccharide

(2017) Wei Zhu et al.   NEUROSCIENCE

Antidepressants induce autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder

(2017) Elísabet Alcocer-Gómez et al.   PHARMACOLOGICAL RESEARCH

Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance

(2016) Je-Wook Yu et al.   ARCHIVES OF PHARMACAL RESEARCH

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

(2016) Masaaki Iwata et al.   BIOLOGICAL PSYCHIATRY

NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

(2016) Yongjun Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

(2016) M-L Wong et al.   MOLECULAR PSYCHIATRY

Cdk5-Dependent Activation of Neuronal Inflammasomes in Parkinson's Disease

(2016) Pei Zhang et al.   MOVEMENT DISORDERS

25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome

(2016) Jiho Jang et al.   Nature Communications

Interferon-alpha treatment induces depression-like behaviour accompanied by elevated hippocampal quinolinic acid levels in rats

(2015) Christina Weide Fischer et al.   BEHAVIOURAL BRAIN RESEARCH

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome

(2015) Elísabet Alcocer-Gómez et al.   MOLECULAR NEUROBIOLOGY

Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling

(2014) Julie Cazareth et al.   Journal of Neuroinflammation

Inflammasomes and Metabolic Disease

(2013) Jorge Henao-Mejia et al.   Annual Review of Physiology

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

(2013) Elísabet Alcocer-Gómez et al.   BRAIN BEHAVIOR AND IMMUNITY

Involvement of Inflammasome Activation in Lipopolysaccharide-induced Mice Depressive-like Behaviors

(2013) Yi Zhang et al.   CNS Neuroscience & Therapeutics

Role of brain transmigrating neutrophils in depression-like behavior during systemic infection

(2013) A Aguliar-Valles et al.   MOLECULAR PSYCHIATRY

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

(2013) Adam K Walker et al.   NEUROPSYCHOPHARMACOLOGY

Cobalt Chloride-induced Hypoxia Ameliorates NLRP3-Mediated Caspase-1 Activation in Mixed Glial Cultures

(2013) Eun-Hee Kim et al.   Immune Network

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

(2012) Haitao Wen et al.   NATURE IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity

(2010) M.R. Hutchinson et al.   NEUROSCIENCE

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration

(2008) Caroline André et al.   JOURNAL OF NEUROIMMUNOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE