Article
Medicine, Research & Experimental
Miroslav Vujasinovic, Elin Marsk, Apostolos Tsolakis, Boel Hynning, Martin Nordberg, Mats Lindblad, Catarina Lindqvist, Lalle H. Nordenvall, Rusana Bark, Peter Elbe
Summary: This study aimed to determine the complication rates after percutaneous endoscopic gastrostomy (PEG) and open gastrostomy (OG) in patients with head and neck cancers (HNCs). The results showed that enteral feeding via gastrostomy is a safe method, regardless of the technique used (PEG or OG), with a low rate of major complications and no mortality linked to the procedure.
Article
Otorhinolaryngology
Anna C. H. Willemsen, Walmari Pilz, Ann Hoeben, Frank J. P. Hoebers, Annemie M. W. J. Schols, Laura W. J. Baijens
Summary: This study investigates the relationship between cancer cachexia and oropharyngeal dysphagia in patients with head and neck cancer. The findings suggest that cachexia independently predicts the presence of patient-reported dysphagia.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Health Care Sciences & Services
Takao Hamamoto, Yuki Sato, Kohei Yumii, Nobuyuki Chikuie, Takayuki Taruya, Yuichiro Horibe, Takashi Ishino, Tsutomu Ueda, Sachio Takeno, Kenichi Yoshimura
Summary: This study evaluated the safety of transcutaneous electrical sensory stimulation (TESS) in head and neck cancer patients undergoing chemoradiotherapy (CRT). The results showed that TESS was feasible and safe during CRT, with no severe adverse reactions. Therefore, TESS has great potential for improving swallowing difficulties in head and neck cancer patients.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Oncology
Petros Alexidis, Petros Bangeas, Konstantinos Efthymiadis, Konstantinos Drevelegkas, Pavlos Kolias
Summary: This study investigated factors associated with dysphagia and the need for percutaneous gastrostomy (PEG) in patients with head and neck cancer undergoing radiation therapy. The results showed that mean dose to pharyngeal constrictor muscles, concurrent chemotherapy, and upper aerodigestive tract malignancies were associated with dysphagia. A threshold of 43 Gy for the mean dose of constrictors was identified for dysphagia. The need for PEG use was correlated with definitive treatment, nasopharyngeal cancer, upper aerodigestive tract cancer, or occult primary malignancies.
Article
Medicine, Research & Experimental
Corina Din-Lovinescu, Gregory L. Barinsky, Roman Povolotskiy, Jordon G. Grube, Chan W. Park
Summary: This study compared outcomes and complications in head and neck cancer (HNC) surgery patients who received a percutaneous endoscopic gastrostomy (PEG) tube on the same day of surgery versus later in hospitalization. The results showed that patients who received a PEG tube on the same day had lower complication rates, shorter length of stay, and decreased hospital costs.
Article
Medicine, Research & Experimental
Maria Giulia Cristofaro, Ida Barca, Francesco Ferragina, Daniela Novembre, Yvelise Ferro, Roberta Pujia, Tiziana Montalcini
Summary: The study found that malnutrition is common in cancer patients, especially in those with head and neck neoplasms, due to dysphagia symptoms and adverse effects of chemotherapy/radiotherapy. Patients with dysphagia were more likely to experience involuntary weight loss and severe malnutrition compared to non-dysphagia patients.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Oncology
Christopher Nutting, Laura Finneran, Justin Roe, Mark A. Sydenham, Matthew Beasley, Shree Bhide, Cheng Boon, Audrey Cook, Emma De Winton, Marie Emson, Bernadette Foran, Robert Frogley, Imran Petkar, Laura Pettit, Keith Rooney, Tom Roques, Devraj Srinivasan, Justine Tyler, DARS Trialist Grp
Summary: The study found that dysphagia-optimised intensity-modulated radiotherapy (DO-IMRT) improved swallowing function and reduced radiation dose-related damage in patients with oropharyngeal and hypopharyngeal cancers. Therefore, DO-IMRT should be considered as a new standard treatment for patients receiving radiotherapy for pharyngeal cancers.
Article
Nutrition & Dietetics
Qing-Qing Xu, Lan-Lan Guo, Jia-Hao Lou, Liu Chen, Ying Wang, Lei Chen, Li-Xia Lu
Summary: This study aimed to compare the clinical outcomes, quality of life, and complication rates of prophylactic percutaneous endoscopic gastrostomy (pPEG) tube, reactive percutaneous endoscopic gastrostomy (rPEG) tube, and reactive nasogastric tube (rNGT) insertion in patients with head and neck cancers. The results showed that prophylactic pPEG could improve nutrition outcomes, reduce treatment delay, and maintain a good quality of life.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Otorhinolaryngology
Claudio Sampieri, Andrea Costantino, Giorgio Gregory Giordano, Michael Dale, Filippo Marchi, Andrea Iandelli, Marta Filauro, Giampiero Parrinello, Gian Marco Pace, Bianca Maria Festa, Giuseppe Spriano, Armando De Virgilio, Giorgio Peretti
Summary: The study developed a prediction model using a scoring system and nomogram to predict the necessity of enteral nutrition for head and neck surgery patients at 28 days postoperatively. The model showed high prediction performances and can guide the development of personalized nutrition protocols.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Nutrition & Dietetics
Diogo Sousa-Catita, Claudia Ferreira-Santos, Paulo Mascarenhas, Catia Oliveira, Raquel Madeira, Carla Adriana Santos, Carla Andre, Catarina Godinho, Luis Antunes, Jorge Fonseca
Summary: This retrospective study evaluated risk markers of poor outcomes in percutaneous endoscopic gastrostomy (PEG)-fed head and neck cancer (HNC) patients. The study analyzed TNM-defined stages, initial anthropometry, and laboratory data. The results showed that advanced cancer stages and low parameters were associated with poor outcomes. Initial MAMC and PEG duration were significant determinants of survival, highlighting the importance of preserving muscle mass and early gastrostomy. The study provides important insights for supporting PEG-fed HNC patients.
Article
Oncology
Aleksandra Kapala, Agnieszka Surwillo-Snarska, Magdalena Jodkiewicz, Andrzej Kawecki
Summary: Patients with head and neck cancer undergoing concurrent chemoradiotherapy or bioradiotherapy are at risk of deteriorating nutritional status leading to increased treatment complications and reduced therapeutic benefit. Nutritional care before and during treatment was shown to improve outcomes by preventing weight loss, complications, and treatment interruptions.
Article
Oncology
Annemieke Kok, Carlijn van der Lugt, Marja J. Leermakers-Vermeer, Nicole M. de Roos, Caroline M. Speksnijder, Remco de Bree
Summary: This study assessed variations in nutritional interventions during chemoradiotherapy among Dutch Head and Neck Oncology centres, revealing substantial differences in dietetic practices, especially in the use of gastrostomy for tube feeding. There is a need for concise dietetic guidelines to standardize practices among different centres.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Article
Oncology
Satoshi Kano, Nayuta Tsushima, Takayoshi Suzuki, Seijiro Hamada, Taizo Yokokawa, Hiroshi Idogawa, Koichi Yasuda, Hideki Minatogawa, Yasuhiro Dekura, Hidefumi Aoyama, Akihiro Homma
Summary: Prophylactic PEG is effective for patients treated with definitive CCRT, especially for those with PS2 or oropharyngeal cancer. The PEG tube use group showed more favorable outcomes in various aspects, but oral intake remains the preferred option.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Otorhinolaryngology
Taru Ilmarinen, Lalle Hammarstedt-Nordenvall, Leif Back, Antti Makitie
Summary: The study assessed policies and perceptions of enteral tube feeding in head and neck cancer patients undergoing chemoradiotherapy in the Nordic countries. Results showed variations in enteral tube feeding practices within and between the Nordic countries. Unified protocols for tube feeding should be developed for this patient population to ensure consistency and optimal care.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Oncology
Patricia Blasco Silva, Gyl Henrique Albrecht Ramos, Ricardo Rasmussen Petterle, Victoria Zeghbi Cochenski Borba
Summary: This study evaluated the relationship between dysphagia and sarcopenia in head and neck cancer patients. It found that patients with dysphagia had a higher prevalence of sarcopenia in the pretreatment phase, which was related to age.
EUROPEAN JOURNAL OF CANCER CARE
(2021)
Review
Otorhinolaryngology
D. G. Grant, P. T. Bradley, D. D. Pothier, D. Bailey, S. Caldera, D. L. Baldwin, M. A. Birchall
CLINICAL OTOLARYNGOLOGY
(2009)
Letter
Otorhinolaryngology
D. G. Grant, P. T. Bradley, A. Parmar, E. C. Toll, D. L. Baldwin, G. C. Porter, P. A. Tierney
CLINICAL OTOLARYNGOLOGY
(2009)
Article
Otorhinolaryngology
P. T. Bradley, V Paleri, J. J. Homer
CLINICAL OTOLARYNGOLOGY
(2012)
Article
Otorhinolaryngology
Patrick J. Bradley, Paula T. Bradley
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
(2010)
Article
Otorhinolaryngology
Patrick J. Bradley, Paula T. Bradley, Kerry D. Olsen
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
(2011)
Review
Otorhinolaryngology
Paula T. Bradley, Patrick J. Bradley
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
(2012)
Review
Otorhinolaryngology
Paula T. Bradley, Patrick J. Bradley
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
(2013)
Article
Medicine, Research & Experimental
Michael Drinnan, Jason Powell, Ali Nikkar-Esfahani, Robert C. Heading, Jill Doyle, S. Michael Griffin, Paula Leslie, Paula T. Bradley, Peter James, Janet A. Wilson
Article
Oncology
Hans Prakash Sathasivam, Ramya Bhatia, Paula Bradley, Andrew Robson, Vinidh Paleri, Helen Cocks, Nashreen Oozeer, Debra Milne, Philip Sloan, Max Robinson
Editorial Material
Medicine, General & Internal
Paula Bradley, Nigel Beasley, Iain Au-Yong
BMJ-BRITISH MEDICAL JOURNAL
(2014)
Article
Otorhinolaryngology
Vinidh Paleri, John Hardman, Theofano Tikka, Paula Bradley, Paul Pracy, Cyrus Kerawala
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2020)
Article
Medicine, General & Internal
Paula Theresa Bradley, Nicola Hall, Gregory Maniatopoulos, Richard D. Neal, Vinidh Paleri, Scott Wilkes
Summary: Qualitative research has highlighted the complexities and mechanisms surrounding the implementation and use of Clinical Cancer Decision Tools (CCDTs) by general practitioners (GPs). GPs find CCDTs useful for increasing awareness of signs and symptoms of undiagnosed cancer, but have concerns about trust in their clinical acumen and referral validity by secondary care clinicians. Additional stakeholder consultation and careful development are crucial for successful uptake of CCDTs in primary care.