4.1 Review

Treatment of tinnitus

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOO.0000000000000185

关键词

auditory pathways; auditory stimulation; brain stimulation; cochlea; differential diagnosis; drug therapy; psychotherapy; randomized controlled trials; symptoms; tinnitus

资金

  1. Tinnitus Research Initiative
  2. German Research Foundation
  3. German Bundesministerium fur Bildung und Forschung
  4. American Tinnitus Association
  5. Astra Zeneca
  6. Cerbomed
  7. Deymed
  8. Magventure
  9. Siemens
  10. Otonomy
  11. European Union (COST)
  12. Lilly
  13. Servier
  14. Pfizer

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Purpose of reviewTinnitus, the perception of sound in the absence of a corresponding external acoustic stimulus, is a highly prevalent and frequently severely impairing disorder with worldwide impact. In this article after a short overview about epidemiology and pathophysiology the currently available treatment options will be discussed with specific consideration of the available evidence, their mechanisms of action and their limitations.Recent findingsDuring the last decades, advances in neuroimaging methods and the development of animal models have contributed to an increasing understanding of the neuronal correlates of tinnitus and have motivated the development of innovative brain-based treatment approaches for directly targeting the neuronal correlates of tinnitus. A further important development has been the insight that there exist different forms of tinnitus that differ in their pathophysiology and their response to specific treatments.SummaryTreatment of tinnitus should be based on a comprehensive diagnosis of etiologic and concomitant aspects of an individual's tinnitus. Already today a large variety of therapeutic interventions are available, which can efficiently reduce tinnitus severity. Several innovative treatment approaches are currently under development.

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