Article
Biochemistry & Molecular Biology
Yeseul Kim, Sanghun Kim, Kiu-Hyung Cho, Jin-Hyung Lee, Jintae Lee
Summary: Bacterial biofilm formation can be effectively inhibited by cinnamaldehyde and its derivatives, especially 4-nitrocinnamaldehyde. These compounds exhibit strong antibiofilm activities against UPEC and S. aureus, making them promising candidates for the treatment of biofilm-associated diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Infectious Diseases
Jiaman Xu, Quan Lin, Maokun Sheng, Ting Ding, Bing Li, Yan Gao, Yulong Tan
Summary: Food contamination caused by bacteria seriously affects public health. Nanotechnology is being used to combat biofilm formation, and this study successfully prepared cinnamaldehyde-chitosan nanoparticles (CSNP-CAs) which showed higher efficacy in removing Staphylococcus aureus biofilms compared to free drugs. The combination of cinnamaldehyde and CSNPs demonstrated the potential of this composite as an efficient therapeutic agent against biofilm.
Article
Environmental Sciences
Jagadish Chandra Kumar Mangu, Marios Stylianou, Per-Erik Olsson, Jana Jass
Summary: The exposure to PFAS increases susceptibility to pathogens in Caenorhabditis elegans by reducing host immunity and increasing intestinal membrane permeability, while also increasing bacterial virulence, with potential implications for humans and other animals.
ENVIRONMENTAL POLLUTION
(2022)
Article
Microbiology
Ayano Tsuru, Yumi Hamazaki, Shuta Tomida, Mohammad Shaokat Ali, Tomomi Komura, Yoshikazu Nishikawa, Eriko Kage-Nakadai
Summary: This study investigated the effects of different Cutibacterium acnes strains on the life span of Caenorhabditis elegans and host resistance against Staphylococcus aureus. It was found that certain strains of C. acnes could shorten the life span of C. elegans, while others, like strain HL110PA4, did not alter it. Additionally, it was discovered that the TIR-1 and p38 MAPK pathways play a role in conferring host resistance against S. aureus in a C. acnes-mediated manner.
MICROBIOLOGY SPECTRUM
(2021)
Article
Biotechnology & Applied Microbiology
Kesia X. F. R. Sena, Raudiney F. Mendes, Evillyn X. Botelho, Rosilma O. Araujo-Melo, Camila J. A. Silva, Henrique N. P. Costa Junior, Bruno Amorim-Carmo, Igor Z. Damasceno, Matheus F. Fernandes-Pedrosa, Jaciana S. Aguiar, Teresinha G. Silva, Glaucia M. S. Lima, Julianna F. C. Albuquerque, Rafael M. Ximenes
Summary: This study aimed to compare the antibacterial effects of two analogue series of thiazolidine-2,4-dione and 4-thioxo-thiazolidin-2-one against multidrug-resistant Staph. aureus clinical isolates. The results showed that one of the analogues demonstrated strong bactericidal effects against Staph. aureus and inhibited biofilm formation. Additionally, the analogue increased the survival rate of Caenorhabditis elegans in an in vivo infection model. It also had no cytotoxicity on human peripheral blood mononuclear cells but showed moderate cytotoxicity on L929 fibroblasts.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Chemistry, Analytical
Jing-Wen Xue, Rui Wang, Jian-Yu Yang, Lu-Xia Wang, Ying Cao, Hui-Da Li, Ting Yang, Jian-Hua Wang
Summary: This paper presents a highly sensitive ELISA method for the detection of Staphylococcus aureus (S. aureus). The method utilizes magnetic beads and gold nanoparticles to capture and quantify S. aureus through a colorimetric reaction. The method provides a high sensitivity and has the potential for both visual detection and microplate reader measurement.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Microbiology
Yunfeng Xu, Weiping Guo, Denglin Luo, Peiyan Li, Jinle Xiang, Junliang Chen, Xiaodong Xia, Qinggang Xie
Summary: This study aimed to investigate the antibiofilm effects of punicalagin against Staphylococcus aureus. The results showed that punicalagin significantly reduced the biomass and metabolic activity of biofilms, decreased the number of viable cells, and damaged the structure of biofilms. The antibiofilm mechanism partly involved the modification of cell surface hydrophobicity. These findings suggest that punicalagin has the potential to be developed as an alternative to control S. aureus biofilms.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Chemistry, Analytical
Xiao-Yan Wang, Jian-Yu Yang, Yi-Ting Wang, Hui-Chao Zhang, Ming-Li Chen, Ting Yang, Jian-Hua Wang
Summary: A surface-enhanced Raman scattering (SERS) nanoprobe based on M13 phages was developed for selective detection and inactivation of Staphylococcus aureus. This method allowed for quantification of S. aureus in aqueous medium and showed promising potential for multifunctional platform for simultaneous detection and inactivation of S. aureus, including bactericidal capabilities.
Article
Multidisciplinary Sciences
Lakshmanan Muthulakshmi, Kannan Suganya, Maruthamuthu Murugan, Jamespandi Annaraj, Veeramuthu Duraipandiyan, Dunia A. Al Farraj, Mohamed S. Elshikh, Annie Juliet, Mukesh Pasupuleti, Jesu Arockiaraj
Summary: This study demonstrates the synthesis of silver nanoparticles using Terminalia catappa leaf extract to inhibit Listeria monocytogenes biofilms. In vitro and in vivo experiments showed the inhibitory effect and non-hazardous nature of the silver nanoparticles.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Spectroscopy
Qin Ouyang, Yongcun Yang, Shujat Ali, Li Wang, Huanhuan Li, Quansheng Chen
Summary: The study developed a rapid, sensitive, and specific aptasensor based on FRET for detecting Staphylococcus aureus in food. Under optimized conditions, there was a significant linear correlation between fluorescence intensity and S. aureus concentration, demonstrating high detection sensitivity and accuracy.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Plant Sciences
Yansheng Zhao, Mei Xiao, Aya Samy Eweys, Juan Bai, Osama M. Darwesh, Xiang Xiao
Summary: This study investigated the effects of cinnamaldehyde in the presence of lactic acid on oxidative stress in Caenorhabditis elegans. It was found that cinnamaldehyde exhibited good antioxidant ability, and the presence of lactic acid could enhance its antioxidant activities. In addition, lactic acid was able to change the metabolic profile of cinnamaldehyde in C. elegans.
PLANT FOODS FOR HUMAN NUTRITION
(2023)
Article
Food Science & Technology
Weiping Guo, Yunfeng Xu, Yangyang Yang, Jinle Xiang, Junliang Chen, Denglin Luo, Qinggang Xie
Summary: Oleuropein has the potential to inhibit the formation of Staphylococcus aureus biofilm and reduce bacterial viability.
Article
Chemistry, Multidisciplinary
Sreejita Ghosh, Somdutta Mondol, Dibyajit Lahiri, Moupriya Nag, Tanmay Sarkar, Siddhartha Pati, Soumya Pandit, Abdullah A. Alarfaj, Mohamad Faiz Mohd Amin, Hisham Atan Edinur, Muhammad Rajaei Ahmad Mohd Zain, Rina Rani Ray
Summary: Tinospora cordifolia, a medicinal plant, has been found to have antimicrobial, anti-inflammatory, anti-diabetic, and anti-cancer properties. The silver nanoparticles made from the leaf extract of T. cordifolia were more effective than the phytoextract in reducing the biofilm of Staphylococcus aureus.
FRONTIERS IN CHEMISTRY
(2023)
Article
Microbiology
Jingyi Yu, Lulin Rao, Lingling Zhan, Yan Zhou, Yinjuan Guo, Xiaocui Wu, Zengqiang Song, Fangyou Yu
Summary: The novel small-molecule ZY-214-4 has the potential to prevent or treat Staphylococcus aureus infections by inhibiting biofilm formation and cell aggregation, without cytotoxicity.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Medicinal
Yong-Guy Kim, Jin-Hyung Lee, Sangbum Lee, Young-Kyung Lee, Buyng Su Hwang, Jintae Lee
Summary: The antibiofilm efficacy of six phorbaketals isolated from the Korean marine sponge Phorbas sp. was investigated, showing that phorbaketal B and phorbaketal C effectively inhibit biofilm formation by Staphylococcus aureus strains. Additionally, phorbaketal B also inhibits staphyloxanthin production, which protects microbes from reactive oxygen species, and both compounds inhibit the expression of biofilm-related genes hla and nuc1.
Article
Nanoscience & Nanotechnology
Mohankandhasamy Ramasamy, Dong Kee Yi, Seong Soo A. An
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2015)
Article
Nanoscience & Nanotechnology
Saravanan Govindaraju, Mohankandhasamy Ramasamy, Rengarajan Baskaran, Sang Jung Ahn, Kyusik Yun
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2015)
Article
Biotechnology & Applied Microbiology
B. Garcia-Lara, M. A. Saucedo-Mora, J. A. Roldan-Sanchez, B. Perez-Eretza, M. Ramasamy, J. Lee, R. Coria-Jimenez, M. Tapia, V. Varela-Guerrero, R. Garcia-Contreras
LETTERS IN APPLIED MICROBIOLOGY
(2015)
Article
Engineering, Biomedical
Mohankandhasamy Ramasamy, Jin-Hyung Lee, Jintae Lee
JOURNAL OF BIOMATERIALS APPLICATIONS
(2016)
Article
Chemistry, Multidisciplinary
Mohankandhasamy Ramasamy, Sanghyo Kim, Su Seong Lee, Dong Kee
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
(2016)
Review
Biotechnology & Applied Microbiology
Mohankandhasamy Ramasamy, Jintae Lee
BIOMED RESEARCH INTERNATIONAL
(2016)
Article
Nanoscience & Nanotechnology
Yuejing Zhu, Mohankandhasamy Ramasamy, Dong Kee Yi
ACS APPLIED MATERIALS & INTERFACES
(2014)
Article
Nanoscience & Nanotechnology
Mohankandhasamy Ramasamy, Minakshi Das, Seong Soo A. An, Dong Kee Yi
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2014)
Article
Materials Science, Multidisciplinary
Mohankandhasamy Ramasamy, Yuejing Zhu, Ungyu Paik, Dong Kee Yi
Article
Materials Science, Multidisciplinary
Mohankandhasamy Ramasamy, Yu Jun Kim, Haiyan Gao, Dong Kee Yi, Jeong Ho An
MATERIALS RESEARCH BULLETIN
(2014)
Article
Nanoscience & Nanotechnology
Duan-Chao Wang, Hou-Yong Yu, Dongming Qi, Mohankandhasamy Ramasamy, Juming Yao, Feng Tang, Kam (Michael) Chiu Tam, Qingqing Ni
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Biochemistry & Molecular Biology
Mohankandhasamy Ramasamy, Sitansu Sekhar Nanda, Jin-Hyung Lee, Jintae Lee
Article
Materials Science, Multidisciplinary
Arjunan Karuppaiah, Karthik Siram, Divakar Selvaraj, Mohankandhasamy Ramasamy, Dinesh Babu, Veintramuthu Sankar
MATERIALS TODAY COMMUNICATIONS
(2020)
Article
Biophysics
Mohankandhasamy Ramasamy, Jin-Hyung Lee, Jintae Lee
COLLOIDS AND SURFACES B-BIOINTERFACES
(2017)