Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell

Ex Vivo Confocal Spectroscopy of Autofluorescence in Age-Related Macular Degeneration

(2016) Joel Kaluzny et al.   PLoS One

The Activation Pathway of Human Rhodopsin in Comparison to Bovine Rhodopsin

(2015) Roman Kazmin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The autophagy-lysosomal pathway

(2015) Daniel L. Kenney et al.   NEUROLOGY

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration

(2015) J Zhang et al.   Cell Death & Disease

Autophagy in the eye: Implications for ocular cell health

(2014) Laura S. Frost et al.   EXPERIMENTAL EYE RESEARCH

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage

(2013) Chao-Peng Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Formation of lipofuscin-like material in the RPE Cell by different components of rod outer segments

(2013) Lei Lei et al.   EXPERIMENTAL EYE RESEARCH

The Ubiquitin–Proteasome System in Retinal Health and Disease

(2013) Laura Campello et al.   MOLECULAR NEUROBIOLOGY

Lipofuscin and the Principles of Fundus Autofluorescence: A Review

(2012) Namrata Nandakumar et al.   Seminars in Ophthalmology

The bisretinoids of retinal pigment epithelium

(2011) Janet R. Sparrow et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Protein Misfolding and Retinal Degeneration

(2011) R. Tzekov et al.   Cold Spring Harbor Perspectives in Biology

Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration

(2011) Patrick M Chen et al.   Cell and Bioscience

The Retinal Pigment Epithelium in Health and Disease

(2010) J. R. Sparrrow et al.   CURRENT MOLECULAR MEDICINE

Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells

(2010) Tim U. Krohne et al.   EXPERIMENTAL EYE RESEARCH

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Phagocytosis of Retinal Rod and Cone Photoreceptors

(2010) Brian M. Kevany et al.   PHYSIOLOGY

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

(2010) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma

(2010) Q.-W. Fan et al.   Science Signaling

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

(2009) Ai Ling Wang et al.   PLoS One

Fundus Autofluorescence and Progression of Age-related Macular Degeneration

(2009) Steffen Schmitz-Valckenberg et al.   SURVEY OF OPHTHALMOLOGY

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Lipofuscin- and melanin-related fundus autofluorescence visualize different retinal pigment epithelial alterations in patients with retinitis pigmentosa

(2008) U Kellner et al.   EYE

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells

(2008) Tuomas Ryhänen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE