Evaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human—Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in Humans-

Arachidonic acid-containing phosphatidylcholine characterized by consolidated plasma and liver lipidomics as an early onset marker for tamoxifen-induced hepatic phospholipidosis

(2017) Kosuke Saito et al.   JOURNAL OF APPLIED TOXICOLOGY

Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury

(2016) Keisuke Goda et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Plasma lipid profiling of different types of hepatic fibrosis induced by carbon tetrachloride and lomustine in rats

(2016) Masaki Ishikawa et al.   Lipids in Health and Disease

Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice

(2016) C. E. Geisler et al.   Nutrition & Metabolism

Increased Hepatic Fatty Acid Uptake and Esterification Contribute to Tetracycline-Induced Steatosis in Mice

(2015) You-Jin Choi et al.   TOXICOLOGICAL SCIENCES

Mechanistic review of drug-induced steatohepatitis

(2015) Justin D. Schumacher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Plasma and Serum Lipidomics of Healthy White Adults Shows Characteristic Profiles by Subjects’ Gender and Age

(2014) Masaki Ishikawa et al.   PLoS One

Whole Genome Transcript Profiling of Drug Induced Steatosis in Rats Reveals a Gene Signature Predictive of Outcome

(2014) Nishika Sahini et al.   PLoS One

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways

(2010) So Young Bu et al.   JOURNAL OF LIPID RESEARCH

Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibitionin vivodoes not alter cardiac long-chain fatty acid uptake and oxidation rates

(2009) Joost J. F. P. Luiken et al.   BIOCHEMICAL JOURNAL

Effects of fenofibrate on plasma and hepatic transaminase activities and hepatic transaminase gene expression in rats

(2009) Akio Kobayashi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Protective effect of bicyclol on tetracycline-induced fatty liver in mice

(2009) Hong-Yan Yu et al.   TOXICOLOGY

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review

(2008) M. F. B. Silva et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver

(2007) Min-Ho Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY