Delineating the Common Biological Pathways Perturbed by ASD’s Genetic Etiology: Lessons from Network-Based Studies
出版年份 2017 全文链接
标题
Delineating the Common Biological Pathways Perturbed by ASD’s Genetic Etiology: Lessons from Network-Based Studies
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 18, Issue 4, Pages 828
出版商
MDPI AG
发表日期
2017-04-18
DOI
10.3390/ijms18040828
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- GeneAnalytics Pathway Analysis and Genetic Overlap among Autism Spectrum Disorder, Bipolar Disorder and Schizophrenia
- (2017) Naveen Khanzada et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Translational use of event-related potentials to assess circuit integrity in ASD
- (2017) Meera E. Modi et al. Nature Reviews Neurology
- High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder
- (2017) Galina Schmunk et al. Scientific Reports
- Rare Inherited and De Novo CNVs Reveal Complex Contributions to ASD Risk in Multiplex Families
- (2016) Virpi M. Leppa et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder
- (2016) Hyopil Kim et al. Behavioral and Brain Functions
- Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects
- (2016) Fengping Dong et al. HUMAN MOLECULAR GENETICS
- Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development
- (2016) K. P. Harris et al. JOURNAL OF NEUROSCIENCE
- Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
- (2016) Omer Durak et al. NATURE NEUROSCIENCE
- How Wnt Signaling Builds the Brain: Bridging Development and Disease
- (2016) Rivka Noelanders et al. NEUROSCIENTIST
- The Ca 2+ /Calmodulin/CaMKK2 Axis: Nature's Metabolic CaMshaft
- (2016) Kathrina L. Marcelo et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Synaptic Wnt/GSK3βSignaling Hub in Autism
- (2016) Mario O. Caracci et al. NEURAL PLASTICITY
- Genetic Syndromes, Maternal Diseases and Antenatal Factors Associated with Autism Spectrum Disorders (ASD)
- (2016) Asher Ornoy et al. Frontiers in Neuroscience
- Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling
- (2016) Ya Wen et al. PLoS One
- Quantitative Proteomics Analysis of CaMKII Phosphorylation and the CaMKII Interactome in the Mouse Forebrain
- (2015) Anthony J. Baucum et al. ACS Chemical Neuroscience
- The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology
- (2015) Jason A. Chen et al. Annual Review of Pathology-Mechanisms of Disease
- Coordinated Spine Pruning and Maturation Mediated by Inter-Spine Competition for Cadherin/Catenin Complexes
- (2015) Wen-Jie Bian et al. CELL
- Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/β-catenin signaling
- (2015) Robert N. Duncan et al. DEVELOPMENT
- Heritability of autism spectrum disorders: a meta-analysis of twin studies
- (2015) Beata Tick et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Whole-genome sequencing of quartet families with autism spectrum disorder
- (2015) Ryan K C Yuen et al. NATURE MEDICINE
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
- (2015) Neelroop N. Parikshak et al. NATURE REVIEWS GENETICS
- Spatiotemporal 16p11.2 Protein Network Implicates Cortical Late Mid-Fetal Brain Development and KCTD13-Cul3-RhoA Pathway in Psychiatric Diseases
- (2015) Guan Ning Lin et al. NEURON
- Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice
- (2015) Dario Cupolillo et al. NEUROPSYCHOPHARMACOLOGY
- Autism spectrum disorder in tuberous sclerosis complex: searching for risk markers
- (2015) Aglaia Vignoli et al. Orphanet Journal of Rare Diseases
- Comparison of human cell signaling pathway databases—evolution, drawbacks and challenges
- (2015) Saikat Chowdhury et al. Database-The Journal of Biological Databases and Curation
- Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model
- (2015) Weirui Guo et al. Cell Reports
- Prevalence of Autism Spectrum Disorder symptoms in children with neurofibromatosis type 1
- (2014) Ellen Plasschaert et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders
- (2014) Regina Waltes et al. HUMAN GENETICS
- Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity
- (2014) J Ellegood et al. MOLECULAR PSYCHIATRY
- The contribution of de novo coding mutations to autism spectrum disorder
- (2014) Ivan Iossifov et al. NATURE
- Most genetic risk for autism resides with common variation
- (2014) Trent Gaugler et al. NATURE GENETICS
- CaMKII: Claiming Center Stage in Postsynaptic Function and Organization
- (2014) Johannes W. Hell NEURON
- Patches of Disorganization in the Neocortex of Children with Autism
- (2014) Rich Stoner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Differences in HPA-axis and heart rate responsiveness to psychosocial stress in children with autism spectrum disorders with and without co-morbid anxiety
- (2014) Matthew J. Hollocks et al. PSYCHONEUROENDOCRINOLOGY
- The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism
- (2014) Dexter Hadley et al. Nature Communications
- Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice
- (2014) Xiaoming Wang et al. Molecular Autism
- mTOR signaling and its roles in normal and abnormal brain development
- (2014) Nobuyuki Takei et al. Frontiers in Molecular Neuroscience
- Glycogen Synthase Kinase-3 Inhibitors Reverse Deficits in Long-term Potentiation and Cognition in Fragile X Mice
- (2013) Aimee V. Franklin et al. BIOLOGICAL PSYCHIATRY
- Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice
- (2013) Aubin Michalon et al. BIOLOGICAL PSYCHIATRY
- Rapamycin improves sociability in the BTBR T+Itpr3tf/J mouse model of autism spectrum disorders
- (2013) Jessica A. Burket et al. BRAIN RESEARCH BULLETIN
- Visualizing CaMKII and CaM activity: a paradigm of compartmentalized signaling
- (2013) Julie Bossuyt et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Axonal Translation of -Catenin Regulates Synaptic Vesicle Dynamics
- (2013) A. M. Taylor et al. JOURNAL OF NEUROSCIENCE
- Structural and molecular interrogation of intact biological systems
- (2013) Kwanghun Chung et al. NATURE
- Fragile X syndrome: a preclinical review on metabotropic glutamate receptor 5 (mGluR5) antagonists and drug development
- (2013) Andreea S. Pop et al. PSYCHOPHARMACOLOGY
- High-Throughput Genetic Screen for Synaptogenic Factors: Identification of LRP6 as Critical for Excitatory Synapse Development
- (2013) Kamal Sharma et al. Cell Reports
- Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders
- (2013) Boryana S Stamova et al. Molecular Autism
- Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex
- (2012) Victoria Tsai et al. CEREBRAL CORTEX
- Impaired induction of long-term potentiation-like plasticity in patients with high-functioning autism and Asperger syndrome
- (2012) NIKOLAI H JUNG et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome
- (2012) C. A. Hoeffer et al. GENES BRAIN AND BEHAVIOR
- Substrate-selective and Calcium-independent Activation of CaMKII by α-Actinin
- (2012) Nidhi Jalan-Sakrikar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant
- (2012) Christelle Golzio et al. NATURE
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
- (2012) Brian J. O’Roak et al. NATURE
- Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex
- (2012) Froylan Calderon de Anda et al. NATURE NEUROSCIENCE
- De Novo Gene Disruptions in Children on the Autistic Spectrum
- (2012) Ivan Iossifov et al. NEURON
- Wnt Signaling in Cancer
- (2012) P. Polakis Cold Spring Harbor Perspectives in Biology
- Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex
- (2012) Atsushi Sato et al. Nature Communications
- Networks of Neuronal Genes Affected by Common and Rare Variants in Autism Spectrum Disorders
- (2012) Eyal Ben-David et al. PLoS Genetics
- NGF, Brain and Behavioral Plasticity
- (2012) Alessandra Berry et al. NEURAL PLASTICITY
- Assessment of 2q23.1 Microdeletion Syndrome Implicates MBD5 as a Single Causal Locus of Intellectual Disability, Epilepsy, and Autism Spectrum Disorder
- (2011) Michael E. Talkowski et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Rett Syndrome
- (2011) Alan K. Percy ARCHIVES OF NEUROLOGY
- Wnt Signaling Has Opposing Roles in the Developing and the Adult Brain That Are Modulated by Hipk1
- (2011) Cinzia Marinaro et al. CEREBRAL CORTEX
- Wnt signaling during synaptic development and plasticity
- (2011) Vivian Budnik et al. CURRENT OPINION IN NEUROBIOLOGY
- Inhibition of GSK3 improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome
- (2011) W. Guo et al. HUMAN MOLECULAR GENETICS
- Synaptic Wnt signaling—a contributor to major psychiatric disorders?
- (2011) Nathan D. Okerlund et al. Journal of Neurodevelopmental Disorders
- QTL replication and targeted association highlight the nerve growth factor gene for nonverbal communication deficits in autism spectrum disorders
- (2011) A T-H Lu et al. MOLECULAR PSYCHIATRY
- Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
- (2011) Brian J O'Roak et al. NATURE GENETICS
- Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
- (2011) Sergiu P Paşca et al. NATURE MEDICINE
- Glycogen Synthase Kinase-3: A Promising Therapeutic Target for Fragile X Syndrome
- (2011) Marjelo A. Mines et al. Frontiers in Molecular Neuroscience
- Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly
- (2010) Kim L. McBride et al. Autism Research
- An Updated Overview on Wnt Signaling Pathways
- (2010) Tata Purushothama Rao et al. CIRCULATION RESEARCH
- Munc18-1 as a key regulator of neurosecretion
- (2010) Gayoung A. Han et al. JOURNAL OF NEUROCHEMISTRY
- Fragile X mice: Reduced long-term potentiation and N-Methyl-D-Aspartate receptor-mediated neurotransmission in dentate gyrus
- (2010) Sung Hwan Yun et al. JOURNAL OF NEUROSCIENCE RESEARCH
- GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism
- (2010) Marjelo A. Mines et al. PLoS One
- Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury
- (2010) David Piccin et al. STEM CELLS
- Fragile X and autism: Intertwined at the molecular level leading to targeted treatments
- (2010) Randi Hagerman et al. Molecular Autism
- Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome
- (2009) B. Chakrabarti et al. Autism Research
- Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
- (2009) Jeffrey J. Hutsler et al. BRAIN RESEARCH
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- A pilot open label, single dose trial of fenobam in adults with fragile X syndrome
- (2009) E Berry-Kravis et al. JOURNAL OF MEDICAL GENETICS
- CaMKII phosphorylation of the GABAAreceptor: receptor subtype- and synapse-specific modulation
- (2009) Catriona M. Houston et al. JOURNAL OF PHYSIOLOGY-LONDON
- Autism: Many Genes, Common Pathways?
- (2008) Daniel H. Geschwind CELL
- Open-Label Treatment Trial of Lithium to Target the Underlying Defect in Fragile X Syndrome
- (2008) Elizabeth Berry-Kravis et al. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
- Roles of Calcium-Stimulated Adenylyl Cyclase and Calmodulin-Dependent Protein Kinase IV in the Regulation of FMRP by Group I Metabotropic Glutamate Receptors
- (2008) H. Wang et al. JOURNAL OF NEUROSCIENCE
- Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential
- (2008) Wenzhong William Min et al. NEUROPHARMACOLOGY
- AutDB: a gene reference resource for autism research
- (2008) Saumyendra N. Basu et al. NUCLEIC ACIDS RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started