期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 18, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/ijms18112252
关键词
toll-like receptors; vitamin D; cardiovascular diseases; atherosclerosis; inflammation
Cardiovascular diseases are the leading cause of mortality worldwide. Therefore, a better understanding of their pathomechanisms and the subsequent implementation of optimal prophylactic and therapeutic strategies are of utmost importance. A growing body of evidence states that low-grade inflammation is a common feature for most of the cardiovascular diseases in which the contributing factors are the activation of toll-like receptors (TLRs) and vitamin D deficiency. In this article, available data concerning the association of cardiovascular diseases with TLRs and vitamin D status are reviewed, followed by a discussion of new possible approaches to cardiovascular disease management.
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